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The map label for this gene is apbE [H]

Identifier: 66045141

GI number: 66045141

Start: 2175268

End: 2176251

Strand: Direct

Name: apbE [H]

Synonym: Psyr_1900

Alternate gene names: 66045141

Gene position: 2175268-2176251 (Clockwise)

Preceding gene: 66045139

Following gene: 66045142

Centisome position: 35.7

GC content: 60.87

Gene sequence:

>984_bases
GTGTTGCTGGTGTGCAGTGGTTGTGGTCAGGAACGCAAGCTGGAAAGCTTTGGCGGGCCGACCATGGGCAGTCATTATTC
CGTGGTGTATGCGCGCGCTTCCGGGCAGCCGGAGCCTGCGGCTGTGCGTCCCGAGGTCGAAGCGATTCTAGACGAGGTCG
ATCAGCAGATGTCGCTCTGGCGCGCGGATTCGGATATCGAGCGCTTCAATGCGTTGCCTGCCAATAGCTGCCAGGTGATG
CCGGAACCGGTCTTGAAACTGATCGGCGTGGGCGAACAGTTGGCGCAGGAGAGCGACGGAGCCTTCGATCTGACGGTCAA
GCCGTTGATGGACCTGTGGGGGTTGGGGCCTCATACGCTGTTCGAGCAGATGCCGCTGGTGCGGCAACTGGCCCGGACTC
AGGCGCTGGTCGGTTATCGCAACCTGCGCATCGTCGGCGACCGGTTGTGCAAGAGTGCCGCCGTGCAAGTGGACCTCAAC
AGCATCGCCGCCGGCTATGCGGTCGATCGGATCAGCGAACGGATGGACGCGCTCGGCTTGCACGATTATCTGGTGCAGGC
CACGGGTGAACTGAAAGTCAGCGGGCTCAAGCCCGACGGCTCGCCCTGGCGGGTGACCCTGGACGCGCCGCTCGATGATG
GCACTGTCACGCAAAAAGTGTTTCCGCTGAAAGGCTACGCCGTGTCTACGTCGGGCGACTATCGTCGCTACGTCGACCAT
GCCGGGTGGCGCATTTCCGATACGCTCGATGCCTTGAGCGGTAAGCCGATCAGCCACAGTCTGGCGTCGGTGACGGTCAT
TCATCCCTCGGCGCTGATGGCTGACGGTCTGTCTTCCCTGCTGTTGATTCTCGGCCCGCAGCGCGGTTGGGATTATGCGC
AAGAACATAAAATCCCTGCTTTTTTTGTGATTCGTGCCGATAAGCGCTTTATCATCCGCAGCAACGCGTCGTTTGATCAT
CTGGTTGTGCAGCAGCCGCGCTAA

Upstream 100 bases:

>100_bases
CTTTTCTGGTTTGTTCGCCGATGGCAGCAAGTCACTCTGAAGGTTTTTTATAGTGCGGGGCATGGGTTTGCGTAGGTTTG
GCAAGGTTGCAGGGTGCCTC

Downstream 100 bases:

>100_bases
GTCAGCGGGCCGGATCATCCGGTCAGTTGCGCCATGTGCAGACAAAAATTGGCCTTCGACGCGACCAAGGGTTAATGTTC
GCCGCCTCGGTGCAGCGCTA

Product: ApbE-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLLVCSGCGQERKLESFGGPTMGSHYSVVYARASGQPEPAAVRPEVEAILDEVDQQMSLWRADSDIERFNALPANSCQVM
PEPVLKLIGVGEQLAQESDGAFDLTVKPLMDLWGLGPHTLFEQMPLVRQLARTQALVGYRNLRIVGDRLCKSAAVQVDLN
SIAAGYAVDRISERMDALGLHDYLVQATGELKVSGLKPDGSPWRVTLDAPLDDGTVTQKVFPLKGYAVSTSGDYRRYVDH
AGWRISDTLDALSGKPISHSLASVTVIHPSALMADGLSSLLLILGPQRGWDYAQEHKIPAFFVIRADKRFIIRSNASFDH
LVVQQPR

Sequences:

>Translated_327_residues
MLLVCSGCGQERKLESFGGPTMGSHYSVVYARASGQPEPAAVRPEVEAILDEVDQQMSLWRADSDIERFNALPANSCQVM
PEPVLKLIGVGEQLAQESDGAFDLTVKPLMDLWGLGPHTLFEQMPLVRQLARTQALVGYRNLRIVGDRLCKSAAVQVDLN
SIAAGYAVDRISERMDALGLHDYLVQATGELKVSGLKPDGSPWRVTLDAPLDDGTVTQKVFPLKGYAVSTSGDYRRYVDH
AGWRISDTLDALSGKPISHSLASVTVIHPSALMADGLSSLLLILGPQRGWDYAQEHKIPAFFVIRADKRFIIRSNASFDH
LVVQQPR
>Mature_327_residues
MLLVCSGCGQERKLESFGGPTMGSHYSVVYARASGQPEPAAVRPEVEAILDEVDQQMSLWRADSDIERFNALPANSCQVM
PEPVLKLIGVGEQLAQESDGAFDLTVKPLMDLWGLGPHTLFEQMPLVRQLARTQALVGYRNLRIVGDRLCKSAAVQVDLN
SIAAGYAVDRISERMDALGLHDYLVQATGELKVSGLKPDGSPWRVTLDAPLDDGTVTQKVFPLKGYAVSTSGDYRRYVDH
AGWRISDTLDALSGKPISHSLASVTVIHPSALMADGLSSLLLILGPQRGWDYAQEHKIPAFFVIRADKRFIIRSNASFDH
LVVQQPR

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=312, Percent_Identity=30.7692307692308, Blast_Score=171, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 35807; Mature: 35807

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVCSGCGQERKLESFGGPTMGSHYSVVYARASGQPEPAAVRPEVEAILDEVDQQMSLW
CEEEECCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
RADSDIERFNALPANSCQVMPEPVLKLIGVGEQLAQESDGAFDLTVKPLMDLWGLGPHTL
CCCCHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCEEEEHHHHHHHHCCCHHHH
FEQMPLVRQLARTQALVGYRNLRIVGDRLCKSAAVQVDLNSIAAGYAVDRISERMDALGL
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCH
HDYLVQATGELKVSGLKPDGSPWRVTLDAPLDDGTVTQKVFPLKGYAVSTSGDYRRYVDH
HHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCCHHHHHHH
AGWRISDTLDALSGKPISHSLASVTVIHPSALMADGLSSLLLILGPQRGWDYAQEHKIPA
CCCEEHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHEEECCCCCCCHHHHCCCCE
FFVIRADKRFIIRSNASFDHLVVQQPR
EEEEECCCEEEEECCCCCCEEEEECCC
>Mature Secondary Structure
MLLVCSGCGQERKLESFGGPTMGSHYSVVYARASGQPEPAAVRPEVEAILDEVDQQMSLW
CEEEECCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
RADSDIERFNALPANSCQVMPEPVLKLIGVGEQLAQESDGAFDLTVKPLMDLWGLGPHTL
CCCCHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCEEEEHHHHHHHHCCCHHHH
FEQMPLVRQLARTQALVGYRNLRIVGDRLCKSAAVQVDLNSIAAGYAVDRISERMDALGL
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCH
HDYLVQATGELKVSGLKPDGSPWRVTLDAPLDDGTVTQKVFPLKGYAVSTSGDYRRYVDH
HHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCCHHHHHHH
AGWRISDTLDALSGKPISHSLASVTVIHPSALMADGLSSLLLILGPQRGWDYAQEHKIPA
CCCEEHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHEEECCCCCCCHHHHCCCCE
FFVIRADKRFIIRSNASFDHLVVQQPR
EEEEECCCEEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]