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The map label for this gene is vanR [H]

Identifier: 66045102

GI number: 66045102

Start: 2135456

End: 2136178

Strand: Direct

Name: vanR [H]

Synonym: Psyr_1858

Alternate gene names: 66045102

Gene position: 2135456-2136178 (Clockwise)

Preceding gene: 66045101

Following gene: 66045104

Centisome position: 35.04

GC content: 56.85

Gene sequence:

>723_bases
ATGTGCAGTGCCATGACAGAAAGCGCAACCAGGGACTTATTGATACAGCAGATGGTGAGCACGATTACCGAGCTCGATGG
GCAGACCGCCATCGAAAATGCACTCGAGTGGTTACGGCGCGAATGCAACAGCGAGCGCGCGATGTTCTTTCAGTTCAAGG
GTCCGCTGTTGCTGACGTTCATCACCTCCAACGTCGACGAAGCGTGGGGCGATGCCTACCGTCAGCACGATCTGATCATG
CAGGACCCGGTAATCCGTTGTTATCGCAATCAACTGGGCTTCCTGAACTGGCAGGATGCGTTCAGGCAATACCCGGTATC
CGCCTTTTATGACGAGCTGGTCGATGCCTGTGAACTGCTTCCGGCCATCTCCTATGGCTATACCAATCATTGCCGTGGTG
CTGACAGCGTGACATCGGTGTGTACCCTGGGCGAAGTGGAGCGGCCCATCAGCGCTGAACAAAAGTACCTCATGAGCAGT
CTCATGCCGGTGCTGCACAGTGTCGCGCGGGGTCTGAAGTTCTGTTCGCGCGGTCTGACCCATCGTGAGCTGGAAGTCTT
GCAGTGGGCCAGAGACGGGAAGACGGCCTGGGAGATCTCGATGATCCGCGACGTGTCGGAGTCGACGGTGAAGTATCACC
TCAAGACCATCTACTCCAAGCTCGGCGTTGCCAACAGGGCACAAGCGGTGGGCGAAGCACTGTGTCGTGGCCTTATCAGA
TAG

Upstream 100 bases:

>100_bases
CCGTTTTTCAACGTGATTATTCGTGTAAGTTCTGCGCCATCGCCAACGGGGTCACGGACAACACCTGTACCGATTCACGG
GCGAACAAGGAGCGGCAGCG

Downstream 100 bases:

>100_bases
TCGGCGGACAAAACGCAGGCAAAAAAAAGCCGCGAGAACAAAGTGTAATCGCGGCAAACAAGGGATGAGAGAGCGTACAG
CGGGTGCCACCCAAGAGGGT

Product: regulatory protein, LuxR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MCSAMTESATRDLLIQQMVSTITELDGQTAIENALEWLRRECNSERAMFFQFKGPLLLTFITSNVDEAWGDAYRQHDLIM
QDPVIRCYRNQLGFLNWQDAFRQYPVSAFYDELVDACELLPAISYGYTNHCRGADSVTSVCTLGEVERPISAEQKYLMSS
LMPVLHSVARGLKFCSRGLTHRELEVLQWARDGKTAWEISMIRDVSESTVKYHLKTIYSKLGVANRAQAVGEALCRGLIR

Sequences:

>Translated_240_residues
MCSAMTESATRDLLIQQMVSTITELDGQTAIENALEWLRRECNSERAMFFQFKGPLLLTFITSNVDEAWGDAYRQHDLIM
QDPVIRCYRNQLGFLNWQDAFRQYPVSAFYDELVDACELLPAISYGYTNHCRGADSVTSVCTLGEVERPISAEQKYLMSS
LMPVLHSVARGLKFCSRGLTHRELEVLQWARDGKTAWEISMIRDVSESTVKYHLKTIYSKLGVANRAQAVGEALCRGLIR
>Mature_240_residues
MCSAMTESATRDLLIQQMVSTITELDGQTAIENALEWLRRECNSERAMFFQFKGPLLLTFITSNVDEAWGDAYRQHDLIM
QDPVIRCYRNQLGFLNWQDAFRQYPVSAFYDELVDACELLPAISYGYTNHCRGADSVTSVCTLGEVERPISAEQKYLMSS
LMPVLHSVARGLKFCSRGLTHRELEVLQWARDGKTAWEISMIRDVSESTVKYHLKTIYSKLGVANRAQAVGEALCRGLIR

Specific function: Probable transcriptional activator. Binds to autoinducer molecule ODHL [H]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788224, Length=190, Percent_Identity=27.8947368421053, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR005143
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03472 Autoind_bind; PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 27293; Mature: 27293

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSAMTESATRDLLIQQMVSTITELDGQTAIENALEWLRRECNSERAMFFQFKGPLLLTF
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEHH
ITSNVDEAWGDAYRQHDLIMQDPVIRCYRNQLGFLNWQDAFRQYPVSAFYDELVDACELL
HHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
PAISYGYTNHCRGADSVTSVCTLGEVERPISAEQKYLMSSLMPVLHSVARGLKFCSRGLT
HHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HRELEVLQWARDGKTAWEISMIRDVSESTVKYHLKTIYSKLGVANRAQAVGEALCRGLIR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCSAMTESATRDLLIQQMVSTITELDGQTAIENALEWLRRECNSERAMFFQFKGPLLLTF
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEHH
ITSNVDEAWGDAYRQHDLIMQDPVIRCYRNQLGFLNWQDAFRQYPVSAFYDELVDACELL
HHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
PAISYGYTNHCRGADSVTSVCTLGEVERPISAEQKYLMSSLMPVLHSVARGLKFCSRGLT
HHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HRELEVLQWARDGKTAWEISMIRDVSESTVKYHLKTIYSKLGVANRAQAVGEALCRGLIR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9139920 [H]