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The map label for this gene is lysN [H]

Identifier: 66045085

GI number: 66045085

Start: 2121278

End: 2122444

Strand: Direct

Name: lysN [H]

Synonym: Psyr_1841

Alternate gene names: 66045085

Gene position: 2121278-2122444 (Clockwise)

Preceding gene: 66045082

Following gene: 66045086

Centisome position: 34.81

GC content: 61.35

Gene sequence:

>1167_bases
ATGGCTTTCTCCGAACGCGTTTCCCGTCTGAAAAGTTCTCTGATTCGCGAGATCCTCGCCGCCGCTCAGTGTCCGGAAGT
GATGTCGTTCGCCGGTGGTCTGCCCGCTGAGTCGATGCTGCCCAAAGTGGAGTGGGCCGACATGCCTGTTGCGCTGGGTC
AGTACGGCATGAGCGAGGGCGAACCTGCGCTGCGCGAAGCGCTGGCCGCCGATGCTCGCGCCCTGGGTATCGACTGCGAT
GCCCGTCAGGTCATGGTGGTCAGCGGTTCTCAGCAGACACTGGATCTGGCGGCCAAGCTGTACATCGACAAAGGCACCGA
AATTCTCCTCGAGGCGCCTACTTATCTGGCGGCGCTGCAGATATTCCAGCTGTTCGGTGCCGACTGCATCACCGTGCCGC
TGCAGGCCGAAGGCCCGGATCTGCTCGCCATGCGTCAGCGTCTGGAACAGCACAAGCCCGCCTTCGCCTACCTCATCCCG
ACGTTCCAGAACCCCTCGGCGGTGCGCTACAGCCAGGCCAGTCGCGATGCCGTTGCGGCCTTGTTCGACGAGTTCGGTGT
CACGTTGATCGAGGACGAGCCCTATCGTGAGTTGAGCTTTGACGGCGGCAGTGCCAGGCCGATCGTCAGCGGTTTGAAGA
CGGCCAGCTGGATTTACACCGGTACGGTTTCCAAGACGCTGCTGCCAGGCCTGCGGGTCGGCTATCTGATCGCCAGCCCC
GATCTGTTTCCGCACTTGCTGCGTCTGAAACAGTCGGCCGATCTGCATACCAATCGCCTCGGCCAGTGGCAGGCCTTGCA
GTGGATTGGTACTGAGCACTATCGTGAGCATCTGGTGACGCTGTGCGAGTTTTACCGGGGCCGTCGTGATGCGTTCGAAA
GTGCCTTGCAAACGCATTTTTCCGACCTGGCCACCTGGAACAGCCCGCAAGGCGGACTGTTCTTCTGGTTGACGCTGAAG
CAGCCGCTGGACACGCGCACCTTGCTGGATACAGCGCTGGCGCACGATGTGGCGTTCATGCCGGGCGAACCTTTCTTTGC
CGATCCGGACGCCAATCACGGTCACTTGCGGCTCAATTTCAGCCATATCGACCCTGCACGGCTCGATGAGGGTATAAAAC
GACTGGCGTCGGTGGTCCGCGCAGCACACCTTCTGCAAGCCGCCTGA

Upstream 100 bases:

>100_bases
TTTTTTAAGGTCAAGCATGTTGACGTATCCGGGTTGATCGTCGTAATTTGAGTCAATCAGTTTGACGTATTTCCAATTGT
CTCGGCTACAGGTAACTGCC

Downstream 100 bases:

>100_bases
TTCAAGACGTCAACATAGACGCAGCAAGGGAGCAGTCTGATGTACAAGGTTTATGGCGATTACAACTCGGGCAACTGCTA
CAAGGTCAAGCTGATGCTTA

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAFSERVSRLKSSLIREILAAAQCPEVMSFAGGLPAESMLPKVEWADMPVALGQYGMSEGEPALREALAADARALGIDCD
ARQVMVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQIFQLFGADCITVPLQAEGPDLLAMRQRLEQHKPAFAYLIP
TFQNPSAVRYSQASRDAVAALFDEFGVTLIEDEPYRELSFDGGSARPIVSGLKTASWIYTGTVSKTLLPGLRVGYLIASP
DLFPHLLRLKQSADLHTNRLGQWQALQWIGTEHYREHLVTLCEFYRGRRDAFESALQTHFSDLATWNSPQGGLFFWLTLK
QPLDTRTLLDTALAHDVAFMPGEPFFADPDANHGHLRLNFSHIDPARLDEGIKRLASVVRAAHLLQAA

Sequences:

>Translated_388_residues
MAFSERVSRLKSSLIREILAAAQCPEVMSFAGGLPAESMLPKVEWADMPVALGQYGMSEGEPALREALAADARALGIDCD
ARQVMVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQIFQLFGADCITVPLQAEGPDLLAMRQRLEQHKPAFAYLIP
TFQNPSAVRYSQASRDAVAALFDEFGVTLIEDEPYRELSFDGGSARPIVSGLKTASWIYTGTVSKTLLPGLRVGYLIASP
DLFPHLLRLKQSADLHTNRLGQWQALQWIGTEHYREHLVTLCEFYRGRRDAFESALQTHFSDLATWNSPQGGLFFWLTLK
QPLDTRTLLDTALAHDVAFMPGEPFFADPDANHGHLRLNFSHIDPARLDEGIKRLASVVRAAHLLQAA
>Mature_387_residues
AFSERVSRLKSSLIREILAAAQCPEVMSFAGGLPAESMLPKVEWADMPVALGQYGMSEGEPALREALAADARALGIDCDA
RQVMVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQIFQLFGADCITVPLQAEGPDLLAMRQRLEQHKPAFAYLIPT
FQNPSAVRYSQASRDAVAALFDEFGVTLIEDEPYRELSFDGGSARPIVSGLKTASWIYTGTVSKTLLPGLRVGYLIASPD
LFPHLLRLKQSADLHTNRLGQWQALQWIGTEHYREHLVTLCEFYRGRRDAFESALQTHFSDLATWNSPQGGLFFWLTLKQ
PLDTRTLLDTALAHDVAFMPGEPFFADPDANHGHLRLNFSHIDPARLDEGIKRLASVVRAAHLLQAA

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=395, Percent_Identity=27.0886075949367, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI33469970, Length=395, Percent_Identity=27.0886075949367, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1787710, Length=378, Percent_Identity=24.6031746031746, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790797, Length=344, Percent_Identity=23.2558139534884, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=24.6113989637306, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=24.6684350132626, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 42834; Mature: 42703

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSERVSRLKSSLIREILAAAQCPEVMSFAGGLPAESMLPKVEWADMPVALGQYGMSEG
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHCCCCCC
EPALREALAADARALGIDCDARQVMVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQ
CHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHEECCCCEEEEECHHHHHHHH
IFQLFGADCITVPLQAEGPDLLAMRQRLEQHKPAFAYLIPTFQNPSAVRYSQASRDAVAA
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
LFDEFGVTLIEDEPYRELSFDGGSARPIVSGLKTASWIYTGTVSKTLLPGLRVGYLIASP
HHHHHCCEEECCCCCCEECCCCCCCCHHHHHHHHHHEEEECCHHHHHCCCCCEEEEEECC
DLFPHLLRLKQSADLHTNRLGQWQALQWIGTEHYREHLVTLCEFYRGRRDAFESALQTHF
HHHHHHHHHHHCCCHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SDLATWNSPQGGLFFWLTLKQPLDTRTLLDTALAHDVAFMPGEPFFADPDANHGHLRLNF
HHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCEEEEEE
SHIDPARLDEGIKRLASVVRAAHLLQAA
CCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFSERVSRLKSSLIREILAAAQCPEVMSFAGGLPAESMLPKVEWADMPVALGQYGMSEG
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHCCCCCC
EPALREALAADARALGIDCDARQVMVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQ
CHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHEECCCCEEEEECHHHHHHHH
IFQLFGADCITVPLQAEGPDLLAMRQRLEQHKPAFAYLIPTFQNPSAVRYSQASRDAVAA
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
LFDEFGVTLIEDEPYRELSFDGGSARPIVSGLKTASWIYTGTVSKTLLPGLRVGYLIASP
HHHHHCCEEECCCCCCEECCCCCCCCHHHHHHHHHHEEEECCHHHHHCCCCCEEEEEECC
DLFPHLLRLKQSADLHTNRLGQWQALQWIGTEHYREHLVTLCEFYRGRRDAFESALQTHF
HHHHHHHHHHHCCCHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SDLATWNSPQGGLFFWLTLKQPLDTRTLLDTALAHDVAFMPGEPFFADPDANHGHLRLNF
HHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCEEEEEE
SHIDPARLDEGIKRLASVVRAAHLLQAA
CCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA