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The map label for this gene is hlyB [H]

Identifier: 66045033

GI number: 66045033

Start: 2040801

End: 2042441

Strand: Reverse

Name: hlyB [H]

Synonym: Psyr_1789

Alternate gene names: 66045033

Gene position: 2042441-2040801 (Counterclockwise)

Preceding gene: 66045034

Following gene: 66045028

Centisome position: 33.52

GC content: 60.15

Gene sequence:

>1641_bases
ATGAAAAATCAGGTTTCTCTGGCTACGCGCATCGGCTTGGGATTCGCCGCTGTCGTCTCGCTGCTCATCTTGATCACAGC
CGTTGGCATTCAGCGGGTCGGGTTCATCGACACCACCCTGGAAGACGTAGGCGAAAATGCCGCCAAGGTGCAGCGCTATG
CGATCAACTTCCGGGGCAGCGTGCATAACCGTGCGATCGCTCTGCGCGACGCCGTGCTGGTCAACAACGACCAGGACATG
GCGCTGCATCTGGCAGAGATGACTCGTCTTGAAAAGGACTATGTCGACTCGGCCGTACCGATGGAGCAGTTGTTCACCAA
GCCCAACGTCAGTGCCGAAGAACGCCAGTTGCTGCGTGGCATCAAGGAAATCGAACAGCAAACGCTCAGCTCTACCAAGA
GCGTGATTGCCTTGCGCCGTGCCGGAGACATCGCCGGTGCGCAGGCCCTGTTGCTGAGCCAGACCTCCGGTAACTACAGT
GAATGGCTGAAGCGCATCAACGCGCTCATCGACCATGAGGAAGCCTCGATCAGGGTCCAGCTGGATAATGTGCAGGCGAC
CGCCAGCCAGTTCCGCGGCCTGATGCTGCTGGCCACTGCGTTCGCTGTGCTGCTGAGCATCGTGCTGTCGGCGTTCATCA
TCCGCTTCGTGAAAAAGACCCTTGGCGCAGAGCCGGTCGACGTTGCCGAGGCCATTCGCCGACTGGCGGCGGGCGATCTG
CAGCAAACCATCACCACGGCGTATCCCGACAGCGTCATGGGCGTGCTGAGAACAGCGCTGAGCCGTCTTTCGGAAACCAT
CACCGACGTACGAATGGCCGCTCAGGAGGTCAGCCAGTCCTCTAGCGTGCTGTCGGCGGCCTCCTCCGCCAACAATGCCC
AGATCATGGTGCAGACCCGTGAAGCCGAACAGGTGGCCACCGCCATCAGCGAGATGGCCGCGACGGTCAGTGAAGTCTCG
GGCTATGCCTCACAGGCCGCGGATGCCGCGCGCCTGGCTGACAGTGAGGTGGCGAGCGGCAACAGCCTCGTTGAAGGTAC
GACCACTGCCATCGAACAACTGGCGGCCACGCTGACTGAAACGACCAGCACCGTGGAGCAGGTCTCACGGCATGGCGAGG
AGATCGAAAAGGTGATCGAGGTGATCAACTCGATTGCCTCACAAACCAACCTGCTGGCGCTCAACGCGGCCATTGAAGCC
GCCCGCGCGGGCGAGCATGGCAGAGGTTTTGCGGTGGTCGCCGATGAGGTTCGTTCGCTGGCCAATCGCACCCAGCTGTC
GACCCAGGAGATTCAGAACATGATCAGCACGCTGCAGGGTGGTACGGAAACTGCGGCACAGAACATGCGCGACAGCTGTG
AACTGGTCAATCGTGCCGTGGAACAGACACGCAATGCCCAAAGCGCCTTGTCGAGAATCAATCAGGAAGTGAGTGCGATC
AATCACATGAACGCGCAGATCGCCAGCGCGTCGGTTCAACAGAGTGCGGTGGCAGAAGACGTTGCGATGAACATCACCAG
CATTCACGACTCGACACTCAAATCTGCCAATGGATCGCAGCAAGTGGCGACCGCCAGTGAGGAACTGGCGCAGCTCGCGG
ATCGCCTGACCCGCAAGGTCGCATTTTTCAAGGCAGGCTGA

Upstream 100 bases:

>100_bases
GCAGTGAGTCGACTGGGCGGTATTGTCAGGCCATTCTGAATAAAGGCTCTTCGCCATTATTTCATTCGACTTCTTCTCTT
GCCTTGCTCGGGTTCATTTC

Downstream 100 bases:

>100_bases
GGGTGTGACGAAGGTGTGATGAGGTATCGCGGCGATGGATTCAGCGTCGCCGCGGTCTCTCATTATTGGCAGATCAGTCG
GTGCAACTGACCGGCTTTGA

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKNQVSLATRIGLGFAAVVSLLILITAVGIQRVGFIDTTLEDVGENAAKVQRYAINFRGSVHNRAIALRDAVLVNNDQDM
ALHLAEMTRLEKDYVDSAVPMEQLFTKPNVSAEERQLLRGIKEIEQQTLSSTKSVIALRRAGDIAGAQALLLSQTSGNYS
EWLKRINALIDHEEASIRVQLDNVQATASQFRGLMLLATAFAVLLSIVLSAFIIRFVKKTLGAEPVDVAEAIRRLAAGDL
QQTITTAYPDSVMGVLRTALSRLSETITDVRMAAQEVSQSSSVLSAASSANNAQIMVQTREAEQVATAISEMAATVSEVS
GYASQAADAARLADSEVASGNSLVEGTTTAIEQLAATLTETTSTVEQVSRHGEEIEKVIEVINSIASQTNLLALNAAIEA
ARAGEHGRGFAVVADEVRSLANRTQLSTQEIQNMISTLQGGTETAAQNMRDSCELVNRAVEQTRNAQSALSRINQEVSAI
NHMNAQIASASVQQSAVAEDVAMNITSIHDSTLKSANGSQQVATASEELAQLADRLTRKVAFFKAG

Sequences:

>Translated_546_residues
MKNQVSLATRIGLGFAAVVSLLILITAVGIQRVGFIDTTLEDVGENAAKVQRYAINFRGSVHNRAIALRDAVLVNNDQDM
ALHLAEMTRLEKDYVDSAVPMEQLFTKPNVSAEERQLLRGIKEIEQQTLSSTKSVIALRRAGDIAGAQALLLSQTSGNYS
EWLKRINALIDHEEASIRVQLDNVQATASQFRGLMLLATAFAVLLSIVLSAFIIRFVKKTLGAEPVDVAEAIRRLAAGDL
QQTITTAYPDSVMGVLRTALSRLSETITDVRMAAQEVSQSSSVLSAASSANNAQIMVQTREAEQVATAISEMAATVSEVS
GYASQAADAARLADSEVASGNSLVEGTTTAIEQLAATLTETTSTVEQVSRHGEEIEKVIEVINSIASQTNLLALNAAIEA
ARAGEHGRGFAVVADEVRSLANRTQLSTQEIQNMISTLQGGTETAAQNMRDSCELVNRAVEQTRNAQSALSRINQEVSAI
NHMNAQIASASVQQSAVAEDVAMNITSIHDSTLKSANGSQQVATASEELAQLADRLTRKVAFFKAG
>Mature_546_residues
MKNQVSLATRIGLGFAAVVSLLILITAVGIQRVGFIDTTLEDVGENAAKVQRYAINFRGSVHNRAIALRDAVLVNNDQDM
ALHLAEMTRLEKDYVDSAVPMEQLFTKPNVSAEERQLLRGIKEIEQQTLSSTKSVIALRRAGDIAGAQALLLSQTSGNYS
EWLKRINALIDHEEASIRVQLDNVQATASQFRGLMLLATAFAVLLSIVLSAFIIRFVKKTLGAEPVDVAEAIRRLAAGDL
QQTITTAYPDSVMGVLRTALSRLSETITDVRMAAQEVSQSSSVLSAASSANNAQIMVQTREAEQVATAISEMAATVSEVS
GYASQAADAARLADSEVASGNSLVEGTTTAIEQLAATLTETTSTVEQVSRHGEEIEKVIEVINSIASQTNLLALNAAIEA
ARAGEHGRGFAVVADEVRSLANRTQLSTQEIQNMISTLQGGTETAAQNMRDSCELVNRAVEQTRNAQSALSRINQEVSAI
NHMNAQIASASVQQSAVAEDVAMNITSIHDSTLKSANGSQQVATASEELAQLADRLTRKVAFFKAG

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=389, Percent_Identity=30.8483290488432, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1787690, Length=428, Percent_Identity=29.4392523364486, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI2367378, Length=362, Percent_Identity=29.8342541436464, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788195, Length=313, Percent_Identity=32.5878594249201, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=30.8, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58307; Mature: 58307

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQVSLATRIGLGFAAVVSLLILITAVGIQRVGFIDTTLEDVGENAAKVQRYAINFRGS
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHCCCC
VHNRAIALRDAVLVNNDQDMALHLAEMTRLEKDYVDSAVPMEQLFTKPNVSAEERQLLRG
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHH
IKEIEQQTLSSTKSVIALRRAGDIAGAQALLLSQTSGNYSEWLKRINALIDHEEASIRVQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEE
LDNVQATASQFRGLMLLATAFAVLLSIVLSAFIIRFVKKTLGAEPVDVAEAIRRLAAGDL
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QQTITTAYPDSVMGVLRTALSRLSETITDVRMAAQEVSQSSSVLSAASSANNAQIMVQTR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEH
EAEQVATAISEMAATVSEVSGYASQAADAARLADSEVASGNSLVEGTTTAIEQLAATLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
TTSTVEQVSRHGEEIEKVIEVINSIASQTNLLALNAAIEAARAGEHGRGFAVVADEVRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ANRTQLSTQEIQNMISTLQGGTETAAQNMRDSCELVNRAVEQTRNAQSALSRINQEVSAI
HHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NHMNAQIASASVQQSAVAEDVAMNITSIHDSTLKSANGSQQVATASEELAQLADRLTRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AFFKAG
HHHCCC
>Mature Secondary Structure
MKNQVSLATRIGLGFAAVVSLLILITAVGIQRVGFIDTTLEDVGENAAKVQRYAINFRGS
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHCCCC
VHNRAIALRDAVLVNNDQDMALHLAEMTRLEKDYVDSAVPMEQLFTKPNVSAEERQLLRG
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHH
IKEIEQQTLSSTKSVIALRRAGDIAGAQALLLSQTSGNYSEWLKRINALIDHEEASIRVQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEE
LDNVQATASQFRGLMLLATAFAVLLSIVLSAFIIRFVKKTLGAEPVDVAEAIRRLAAGDL
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QQTITTAYPDSVMGVLRTALSRLSETITDVRMAAQEVSQSSSVLSAASSANNAQIMVQTR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEH
EAEQVATAISEMAATVSEVSGYASQAADAARLADSEVASGNSLVEGTTTAIEQLAATLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
TTSTVEQVSRHGEEIEKVIEVINSIASQTNLLALNAAIEAARAGEHGRGFAVVADEVRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ANRTQLSTQEIQNMISTLQGGTETAAQNMRDSCELVNRAVEQTRNAQSALSRINQEVSAI
HHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NHMNAQIASASVQQSAVAEDVAMNITSIHDSTLKSANGSQQVATASEELAQLADRLTRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AFFKAG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]