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The map label for this gene is yajO [H]

Identifier: 66045034

GI number: 66045034

Start: 2042710

End: 2043705

Strand: Reverse

Name: yajO [H]

Synonym: Psyr_1790

Alternate gene names: 66045034

Gene position: 2043705-2042710 (Counterclockwise)

Preceding gene: 66045040

Following gene: 66045033

Centisome position: 33.54

GC content: 59.64

Gene sequence:

>996_bases
ATGGACTACGTAAAGCTTGGCAACACAGGACTGGATATTTCCAGACTGTGCCTGGGATGCATGACATTCGGCGAGCCCGA
TGCCGGAACGCATCCCTGGACACTGGGCGAAGAAGCAAGCAGACCGATCATCAAACACGCCGTCGAGCAAGGCATCAATT
TTTTTGACACGGCCAATAGCTACTCGGCAGGTACTTCGGAAACCATCGTCGGTAAATTGCTCAAAGAGTTCACACGTCGC
GACGAGACCGTGATCGCCACGAAGGTGTTCTTTCCGGCAAACATGTGGGAAGGCTCGACCCGCCCCAACGAAAAGGGGCT
CTCGCGCAAGGCCATCATGTCCAGTATCGACGCGAGCCTGACGCGACTCGGCACTGACTATGTCGACCTGTACCAGATCC
ATCGCTGGGACTATGACACGCCCATCGAAGAAACCATGGAAGCCCTGCACGATGTGGTCAGGGCCGGCAAGGCCAGGTAC
ATCGGCGCGTCTTCCATGTACGTATGGCAGTTCGCCAAGGCCCAGCAGGTCGCGACCGCGCATGGCTGGAGCAGGTTCGT
CTCGATGCAGAACTACCTGAACCTGGTCTATCGCGAAGAAGAGCGCGAGATGATCCCGCTGTGTATCGATCAGGGGGTCG
GCCTGATGCCGTGGAGCCCGATGGCACGCGGCAGGCTGACCAGGCCCCATGGTCAGCAGACCGAGCGGACCAGAACCGAC
GTATCCGGCCAGTCGTTTTACGAGGCGACAGAAAAGGAAGACGGTCGCGTGATCGATGCCGTGGAACAGCTGGCCGCAGA
GCGCGGGGTGCCGATGGCGCAAATCGCACTGGCCTGGGTATTGGCCAAGCGCGGTGTATCCGCGCCCATCGTCGGCGCCT
CCAAGGCGACGCAACTGGACGATGCCATCGCGGCACTGCAACTGGTGCTCAGTGATGAGGACATCAAACGCCTCGAGGCA
CCGTACGTGCCCCATGCAGTAACCGGATTCGTCTGA

Upstream 100 bases:

>100_bases
GAACCAATCGCGTCAAAGCGAGTTGTTCCGGGCAGACGTTGCCCAACTGTAAACGCGAAACGGCTCGGCGGCTGCTCAAT
CAACGATAGACGGAGGATTC

Downstream 100 bases:

>100_bases
CCGGCGCTGCAAACACCCCGGAAACCGGCGAACGGCATGAGCCTCGCCGGTTACCCGCTGCACACAGCGACGACGAGCGC
CGGTAAAGATCGCACCGTAC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MDYVKLGNTGLDISRLCLGCMTFGEPDAGTHPWTLGEEASRPIIKHAVEQGINFFDTANSYSAGTSETIVGKLLKEFTRR
DETVIATKVFFPANMWEGSTRPNEKGLSRKAIMSSIDASLTRLGTDYVDLYQIHRWDYDTPIEETMEALHDVVRAGKARY
IGASSMYVWQFAKAQQVATAHGWSRFVSMQNYLNLVYREEEREMIPLCIDQGVGLMPWSPMARGRLTRPHGQQTERTRTD
VSGQSFYEATEKEDGRVIDAVEQLAAERGVPMAQIALAWVLAKRGVSAPIVGASKATQLDDAIAALQLVLSDEDIKRLEA
PYVPHAVTGFV

Sequences:

>Translated_331_residues
MDYVKLGNTGLDISRLCLGCMTFGEPDAGTHPWTLGEEASRPIIKHAVEQGINFFDTANSYSAGTSETIVGKLLKEFTRR
DETVIATKVFFPANMWEGSTRPNEKGLSRKAIMSSIDASLTRLGTDYVDLYQIHRWDYDTPIEETMEALHDVVRAGKARY
IGASSMYVWQFAKAQQVATAHGWSRFVSMQNYLNLVYREEEREMIPLCIDQGVGLMPWSPMARGRLTRPHGQQTERTRTD
VSGQSFYEATEKEDGRVIDAVEQLAAERGVPMAQIALAWVLAKRGVSAPIVGASKATQLDDAIAALQLVLSDEDIKRLEA
PYVPHAVTGFV
>Mature_331_residues
MDYVKLGNTGLDISRLCLGCMTFGEPDAGTHPWTLGEEASRPIIKHAVEQGINFFDTANSYSAGTSETIVGKLLKEFTRR
DETVIATKVFFPANMWEGSTRPNEKGLSRKAIMSSIDASLTRLGTDYVDLYQIHRWDYDTPIEETMEALHDVVRAGKARY
IGASSMYVWQFAKAQQVATAHGWSRFVSMQNYLNLVYREEEREMIPLCIDQGVGLMPWSPMARGRLTRPHGQQTERTRTD
VSGQSFYEATEKEDGRVIDAVEQLAAERGVPMAQIALAWVLAKRGVSAPIVGASKATQLDDAIAALQLVLSDEDIKRLEA
PYVPHAVTGFV

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=318, Percent_Identity=33.3333333333333, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI4504825, Length=316, Percent_Identity=33.2278481012658, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI27436964, Length=318, Percent_Identity=33.3333333333333, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI27436962, Length=318, Percent_Identity=33.3333333333333, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI27436971, Length=319, Percent_Identity=33.8557993730408, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI27436966, Length=318, Percent_Identity=33.0188679245283, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI223718702, Length=309, Percent_Identity=27.5080906148867, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI41327764, Length=301, Percent_Identity=28.2392026578073, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI41152114, Length=309, Percent_Identity=26.2135922330097, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI223718708, Length=142, Percent_Identity=34.5070422535211, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=57.2727272727273, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1789375, Length=332, Percent_Identity=32.8313253012048, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=30.635838150289, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=32.3353293413174, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788081, Length=304, Percent_Identity=28.2894736842105, Blast_Score=101, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=43.75, Blast_Score=287, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6323998, Length=327, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319958, Length=307, Percent_Identity=32.8990228013029, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319951, Length=287, Percent_Identity=33.1010452961672, Blast_Score=142, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6322615, Length=257, Percent_Identity=33.852140077821, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6321052, Length=153, Percent_Identity=31.3725490196078, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640980, Length=333, Percent_Identity=28.5285285285285, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45549126, Length=333, Percent_Identity=28.5285285285285, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646155, Length=328, Percent_Identity=27.7439024390244, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646159, Length=173, Percent_Identity=32.9479768786127, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36796; Mature: 36796

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYVKLGNTGLDISRLCLGCMTFGEPDAGTHPWTLGEEASRPIIKHAVEQGINFFDTANS
CCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCHHCCCCC
YSAGTSETIVGKLLKEFTRRDETVIATKVFFPANMWEGSTRPNEKGLSRKAIMSSIDASL
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCHHCCHHHHHHHHHHHHH
TRLGTDYVDLYQIHRWDYDTPIEETMEALHDVVRAGKARYIGASSMYVWQFAKAQQVATA
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHH
HGWSRFVSMQNYLNLVYREEEREMIPLCIDQGVGLMPWSPMARGRLTRPHGQQTERTRTD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHC
VSGQSFYEATEKEDGRVIDAVEQLAAERGVPMAQIALAWVLAKRGVSAPIVGASKATQLD
CCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
DAIAALQLVLSDEDIKRLEAPYVPHAVTGFV
HHHHHHHHHHCCHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MDYVKLGNTGLDISRLCLGCMTFGEPDAGTHPWTLGEEASRPIIKHAVEQGINFFDTANS
CCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCHHCCCCC
YSAGTSETIVGKLLKEFTRRDETVIATKVFFPANMWEGSTRPNEKGLSRKAIMSSIDASL
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCHHCCHHHHHHHHHHHHH
TRLGTDYVDLYQIHRWDYDTPIEETMEALHDVVRAGKARYIGASSMYVWQFAKAQQVATA
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHH
HGWSRFVSMQNYLNLVYREEEREMIPLCIDQGVGLMPWSPMARGRLTRPHGQQTERTRTD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHC
VSGQSFYEATEKEDGRVIDAVEQLAAERGVPMAQIALAWVLAKRGVSAPIVGASKATQLD
CCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
DAIAALQLVLSDEDIKRLEAPYVPHAVTGFV
HHHHHHHHHHCCHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]