Click here to switch to the map view.

The map label for this gene is ybdL [H]

Identifier: 66044501

GI number: 66044501

Start: 1409314

End: 1410462

Strand: Direct

Name: ybdL [H]

Synonym: Psyr_1253

Alternate gene names: 66044501

Gene position: 1409314-1410462 (Clockwise)

Preceding gene: 66044500

Following gene: 66044502

Centisome position: 23.13

GC content: 59.7

Gene sequence:

>1149_bases
ATGATCGACAGCAAGTTGCCCAACGTGGGCACCACTATCTTCACCGTCATGTCACAGCTGGCCGCCGAAACCGGGGCTAT
CAACCTGTCCCAGGGGTTTCCCGATTTTGACGGGCCGCAGGCGCTGCGTGATGCAGTCTGCCGACACGTCACTCAAGGCC
ATAACCAATACTCACCGATGACCGGCCTGCCTGCGCTTCGTCAGCAAGTCGCGGCAAAGATCGCCCGCAGCTATGGGCGT
ACGGTCAATCCGGACAGCGAAATCACCATCACGCCGGGTGCCACGCAGGCGATTTTCTGCGCGATCCACAGCGTTATTCG
CGCTGGCGACGAAGTGATCATTTTCGACCCTTGCTATGACAGCTACGAGCCCGCCGTCGAACTGGCCGGTGGGCGCTGCG
TGCATGTGCAACTGGGGCTGGATGACTTCTCCATCGACTGGCAAAAGCTCAGCGATGCGCTAAGCCCGCGTACCCGCATG
ATCGTCATCAACAGCCCGCACAACCCCAGCGGCGCGTTGATCAGCCGTGCAGAGCTCGATCGGCTGGCCGCGCTGATCGC
CGATCGCGACATCTACCTGCTCAGCGACGAAGTCTATGAGCACCTGGTGTTCGACGGCGCACGCCATGTCAGTGTGCTTG
ATCACGAAGCGTTGTATCAGCGCGCCTTCGTCGTCAGCTCGTTCGGCAAGACCTATCACGTCACTGGCTGGAAAACCGGC
TATGTGGTCGCGCCGCCAGCATTGAGCGCCGAGTTGCGCAAGGTGCATCAGTATGTGAGCTTCTGCGGTGTCACGCCTTT
GCAGTACGCGTTGGCCGACTTCATGGCCGAACACCCGGAGCATGTCGATGAACTGCCAGGCTTTTATCAGGCCAAGCGCG
ACTTTTTCTGTGGTCATCTGGCCGAGTCGCGTTTCAGCTTCCGGCCGGTGGGCGGGACTTATTTCCAGTTGGTCGATTAC
TCGCAGATCAGGCCCGACCTCAACGATGTCGACATGGCCTTGTGGATGACCCGTGAACACGGTGTGGCGAGCATTCCGAT
TTCTGTGTTCTACCAGAGCCCGCCAGCAGGGCAGCGCCTGATCCGCCTGTGCTTTGCCAAACAGGAAGAGACGTTGCGTC
AGGCGGCGGAGAAACTATGCGCGATCTAA

Upstream 100 bases:

>100_bases
GGGAAAAAGGCGCTTCGGCGCCTTTTTTTGTGGCCGTTTAATGGGCTATCCTGCCTGACCCGTGCCGCCCGGTGCCGGGA
GATTGCAGGGAAAGGGTTCC

Downstream 100 bases:

>100_bases
GCGGGCTGCCGAACCTCAACCTCGCGCTGATCCAGACCACGCTGGCGTGGCATGATCGCGAGGCCAATCTCGAGCATTTC
GAGCCATTACTGGATGAGGC

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MIDSKLPNVGTTIFTVMSQLAAETGAINLSQGFPDFDGPQALRDAVCRHVTQGHNQYSPMTGLPALRQQVAAKIARSYGR
TVNPDSEITITPGATQAIFCAIHSVIRAGDEVIIFDPCYDSYEPAVELAGGRCVHVQLGLDDFSIDWQKLSDALSPRTRM
IVINSPHNPSGALISRAELDRLAALIADRDIYLLSDEVYEHLVFDGARHVSVLDHEALYQRAFVVSSFGKTYHVTGWKTG
YVVAPPALSAELRKVHQYVSFCGVTPLQYALADFMAEHPEHVDELPGFYQAKRDFFCGHLAESRFSFRPVGGTYFQLVDY
SQIRPDLNDVDMALWMTREHGVASIPISVFYQSPPAGQRLIRLCFAKQEETLRQAAEKLCAI

Sequences:

>Translated_382_residues
MIDSKLPNVGTTIFTVMSQLAAETGAINLSQGFPDFDGPQALRDAVCRHVTQGHNQYSPMTGLPALRQQVAAKIARSYGR
TVNPDSEITITPGATQAIFCAIHSVIRAGDEVIIFDPCYDSYEPAVELAGGRCVHVQLGLDDFSIDWQKLSDALSPRTRM
IVINSPHNPSGALISRAELDRLAALIADRDIYLLSDEVYEHLVFDGARHVSVLDHEALYQRAFVVSSFGKTYHVTGWKTG
YVVAPPALSAELRKVHQYVSFCGVTPLQYALADFMAEHPEHVDELPGFYQAKRDFFCGHLAESRFSFRPVGGTYFQLVDY
SQIRPDLNDVDMALWMTREHGVASIPISVFYQSPPAGQRLIRLCFAKQEETLRQAAEKLCAI
>Mature_382_residues
MIDSKLPNVGTTIFTVMSQLAAETGAINLSQGFPDFDGPQALRDAVCRHVTQGHNQYSPMTGLPALRQQVAAKIARSYGR
TVNPDSEITITPGATQAIFCAIHSVIRAGDEVIIFDPCYDSYEPAVELAGGRCVHVQLGLDDFSIDWQKLSDALSPRTRM
IVINSPHNPSGALISRAELDRLAALIADRDIYLLSDEVYEHLVFDGARHVSVLDHEALYQRAFVVSSFGKTYHVTGWKTG
YVVAPPALSAELRKVHQYVSFCGVTPLQYALADFMAEHPEHVDELPGFYQAKRDFFCGHLAESRFSFRPVGGTYFQLVDY
SQIRPDLNDVDMALWMTREHGVASIPISVFYQSPPAGQRLIRLCFAKQEETLRQAAEKLCAI

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=407, Percent_Identity=32.1867321867322, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI56713256, Length=408, Percent_Identity=32.1078431372549, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=33.0808080808081, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=33.0808080808081, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI169881281, Length=396, Percent_Identity=29.5454545454545, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI4507369, Length=346, Percent_Identity=23.6994219653179, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786816, Length=376, Percent_Identity=54.2553191489362, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1788722, Length=362, Percent_Identity=22.0994475138122, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788627, Length=277, Percent_Identity=27.0758122743682, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787710, Length=277, Percent_Identity=26.3537906137184, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790797, Length=295, Percent_Identity=23.728813559322, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=403, Percent_Identity=34.7394540942928, Blast_Score=227, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI71994472, Length=403, Percent_Identity=34.7394540942928, Blast_Score=227, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17567369, Length=410, Percent_Identity=33.6585365853659, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17567663, Length=233, Percent_Identity=22.7467811158798, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=386, Percent_Identity=32.1243523316062, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=35.7142857142857, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=35.7142857142857, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=35.7142857142857, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=35.7142857142857, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI18859735, Length=279, Percent_Identity=25.089605734767, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42353; Mature: 42353

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSKLPNVGTTIFTVMSQLAAETGAINLSQGFPDFDGPQALRDAVCRHVTQGHNQYSPM
CCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
TGLPALRQQVAAKIARSYGRTVNPDSEITITPGATQAIFCAIHSVIRAGDEVIIFDPCYD
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCC
SYEPAVELAGGRCVHVQLGLDDFSIDWQKLSDALSPRTRMIVINSPHNPSGALISRAELD
CCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHH
RLAALIADRDIYLLSDEVYEHLVFDGARHVSVLDHEALYQRAFVVSSFGKTYHVTGWKTG
HHHHHHHCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
YVVAPPALSAELRKVHQYVSFCGVTPLQYALADFMAEHPEHVDELPGFYQAKRDFFCGHL
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHH
AESRFSFRPVGGTYFQLVDYSQIRPDLNDVDMALWMTREHGVASIPISVFYQSPPAGQRL
HHCCCCEECCCCCEEEEECHHHHCCCCCCCCEEEEEECCCCCEECCEEEEECCCCHHHHH
IRLCFAKQEETLRQAAEKLCAI
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDSKLPNVGTTIFTVMSQLAAETGAINLSQGFPDFDGPQALRDAVCRHVTQGHNQYSPM
CCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
TGLPALRQQVAAKIARSYGRTVNPDSEITITPGATQAIFCAIHSVIRAGDEVIIFDPCYD
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCC
SYEPAVELAGGRCVHVQLGLDDFSIDWQKLSDALSPRTRMIVINSPHNPSGALISRAELD
CCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHH
RLAALIADRDIYLLSDEVYEHLVFDGARHVSVLDHEALYQRAFVVSSFGKTYHVTGWKTG
HHHHHHHCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
YVVAPPALSAELRKVHQYVSFCGVTPLQYALADFMAEHPEHVDELPGFYQAKRDFFCGHL
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHH
AESRFSFRPVGGTYFQLVDYSQIRPDLNDVDMALWMTREHGVASIPISVFYQSPPAGQRL
HHCCCCEECCCCCEEEEECHHHHCCCCCCCCEEEEEECCCCCEECCEEEEECCCCHHHHH
IRLCFAKQEETLRQAAEKLCAI
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]