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The map label for this gene is engA [H]

Identifier: 66044500

GI number: 66044500

Start: 1407732

End: 1409204

Strand: Direct

Name: engA [H]

Synonym: Psyr_1252

Alternate gene names: 66044500

Gene position: 1407732-1409204 (Clockwise)

Preceding gene: 66044499

Following gene: 66044501

Centisome position: 23.1

GC content: 60.35

Gene sequence:

>1473_bases
ATGGTTCCCGTAATCGCCCTGGTGGGTCGACCGAACGTCGGCAAGTCCACCATGTTCAACCGCCTGACCAGGACTCGCGA
CGCCATTGTCGGCGATCTGTCCGGTCTTACCCGTGATCGCCAATACGGAGAGGCGAAGTGGCAAGGGCGCTCCTATATTC
TGATCGACACCGGCGGTATCTCCGGTGACGAGCATGGCATGGACGAAAAGATGGCCGAGCAGTCGCTGCTGGCCATTGAA
GAAGCCGATGTGGTGCTGTTTCTGGTGGACGCCCGTGCGGGCTACACCGCTGCTGATCAGATGATTGGTGAGCACCTGCG
CAAGCGCAACAAGCGTTCCTACGTGGTTGCCAACAAGATCGACAACATCGACGAGAACCTGGCGCGTGCCGAGTTCAGCC
CGATGGGTCTGGGCGACGCCATTCCGGTGGCCGGTGCCCACGGCCGTGGCATCTCGCAGATGCTCGAAATCGCCCTGCGG
GAATTCCCCAGGGACGAGGATGAGCCTGAAGAGGGCGTTGAGGTCGAAGAAGTCGCCGAAGGTCAGGAAGCCAAGCGCAT
CCCCGGCCCGAGCGAGAAGGACGGCATCAAGATCGCCATCATCGGTCGTCCCAACGTCGGCAAGTCGACGCTGGTCAACC
GCATGCTGGGTGAAGACCGGGTTATCGTCTATGACGAGCCAGGCACCACGCGCGACAGTATCTACATTCCCTTCGAGCGT
AACGAAGAGAAGTACACGCTGATCGACACCGCCGGTGTGCGCAAGCGCGGCAAGATCCACGAGGAAGTCGAAAAGTTCTC
GGTGGTCAAGACGCTGCAGGCCATCAAGGACGCCAACGTGGTGATCTTTGTGATGGACGCCCGCGAAGGTGTGGTCGACC
ACGACCTGAACCTGCTGGGCTTCGCCCTTGAAGCGGGTCGTGCGCTGGTCATCGCGCTGAACAAGTGGGACGGCATGACG
CCGGGCGAACGCGATTTCGTGAAGATCGAACTGGAGCGCCGGTTGTTCTTCGTCGACTTCGCCGACATCCACTTTATCTC
GGCCATGCATGGCACGGGCGTGGGCAACCTGTATCAGTCGGTACAGAACTCGTTCAAGTCCGCGGTAACGCGCTGGCCAA
CCAGCCGCCTGACGCAGATTCTCGAAGATGCGGTCAGCGAGCATGCGCCACCGATGGTCGGCAGCCGCCGCATCAAGCTG
CGTTATGCCCACCTGGGGGGTGCCAACCCGCCGCTGATCGTAATCCACGGTAACCAGGTCGAGAAGGTACCCAAGTCCTA
CGTCCGTTATCTGGAAAACACCTACCGGCGTGTGCTCAAGCTGGTCGGTACGCCAATCCGTATCGAGTTCAAGGGCGGCG
AGAACCCGTATGAAGGCAACAAGAACACGCTCACTGACCGTCAGGTCAACAAGAAGCGTCGGATGATGTCGCACCACAAG
AAGGCCGACAAGAAGCGCCGCGACAAGCGCTGA

Upstream 100 bases:

>100_bases
CTTCGGCAAGGCTGCGGTGCCTTTGTGGCATCGCCCCGAACTCCGGCCGCTGCCCTGCAGCGGCTTTTGTATTTTCTGAA
ATAACGAAGTGGAGAGCCGC

Downstream 100 bases:

>100_bases
GTCAGCATCGGGAAAAAGGCGCTTCGGCGCCTTTTTTTGTGGCCGTTTAATGGGCTATCCTGCCTGACCCGTGCCGCCCG
GTGCCGGGAGATTGCAGGGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MVPVIALVGRPNVGKSTMFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGISGDEHGMDEKMAEQSLLAIE
EADVVLFLVDARAGYTAADQMIGEHLRKRNKRSYVVANKIDNIDENLARAEFSPMGLGDAIPVAGAHGRGISQMLEIALR
EFPRDEDEPEEGVEVEEVAEGQEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDEPGTTRDSIYIPFER
NEEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLGFALEAGRALVIALNKWDGMT
PGERDFVKIELERRLFFVDFADIHFISAMHGTGVGNLYQSVQNSFKSAVTRWPTSRLTQILEDAVSEHAPPMVGSRRIKL
RYAHLGGANPPLIVIHGNQVEKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRMMSHHK
KADKKRRDKR

Sequences:

>Translated_490_residues
MVPVIALVGRPNVGKSTMFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGISGDEHGMDEKMAEQSLLAIE
EADVVLFLVDARAGYTAADQMIGEHLRKRNKRSYVVANKIDNIDENLARAEFSPMGLGDAIPVAGAHGRGISQMLEIALR
EFPRDEDEPEEGVEVEEVAEGQEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDEPGTTRDSIYIPFER
NEEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLGFALEAGRALVIALNKWDGMT
PGERDFVKIELERRLFFVDFADIHFISAMHGTGVGNLYQSVQNSFKSAVTRWPTSRLTQILEDAVSEHAPPMVGSRRIKL
RYAHLGGANPPLIVIHGNQVEKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRMMSHHK
KADKKRRDKR
>Mature_490_residues
MVPVIALVGRPNVGKSTMFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGISGDEHGMDEKMAEQSLLAIE
EADVVLFLVDARAGYTAADQMIGEHLRKRNKRSYVVANKIDNIDENLARAEFSPMGLGDAIPVAGAHGRGISQMLEIALR
EFPRDEDEPEEGVEVEEVAEGQEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDEPGTTRDSIYIPFER
NEEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLGFALEAGRALVIALNKWDGMT
PGERDFVKIELERRLFFVDFADIHFISAMHGTGVGNLYQSVQNSFKSAVTRWPTSRLTQILEDAVSEHAPPMVGSRRIKL
RYAHLGGANPPLIVIHGNQVEKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRMMSHHK
KADKKRRDKR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=499, Percent_Identity=58.1162324649299, Blast_Score=575, Evalue=1e-165,
Organism=Escherichia coli, GI1788919, Length=165, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI2367268, Length=94, Percent_Identity=38.2978723404255, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=213, Percent_Identity=28.169014084507, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 54993; Mature: 54993

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVIALVGRPNVGKSTMFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCC
SGDEHGMDEKMAEQSLLAIEEADVVLFLVDARAGYTAADQMIGEHLRKRNKRSYVVANKI
CCCCCCCHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCC
DNIDENLARAEFSPMGLGDAIPVAGAHGRGISQMLEIALREFPRDEDEPEEGVEVEEVAE
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCHHHHHC
GQEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDEPGTTRDSIYIPFER
CCHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEC
NEEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLG
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHH
FALEAGRALVIALNKWDGMTPGERDFVKIELERRLFFVDFADIHFISAMHGTGVGNLYQS
HHHCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEEEHHHHHHHHHCCCCHHHHHHH
VQNSFKSAVTRWPTSRLTQILEDAVSEHAPPMVGSRRIKLRYAHLGGANPPLIVIHGNQV
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEECCHH
EKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRMMSHHK
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KADKKRRDKR
HHHHHHCCCC
>Mature Secondary Structure
MVPVIALVGRPNVGKSTMFNRLTRTRDAIVGDLSGLTRDRQYGEAKWQGRSYILIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCC
SGDEHGMDEKMAEQSLLAIEEADVVLFLVDARAGYTAADQMIGEHLRKRNKRSYVVANKI
CCCCCCCHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCC
DNIDENLARAEFSPMGLGDAIPVAGAHGRGISQMLEIALREFPRDEDEPEEGVEVEEVAE
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCHHHHHC
GQEAKRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEDRVIVYDEPGTTRDSIYIPFER
CCHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEC
NEEKYTLIDTAGVRKRGKIHEEVEKFSVVKTLQAIKDANVVIFVMDAREGVVDHDLNLLG
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHH
FALEAGRALVIALNKWDGMTPGERDFVKIELERRLFFVDFADIHFISAMHGTGVGNLYQS
HHHCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEEEHHHHHHHHHCCCCHHHHHHH
VQNSFKSAVTRWPTSRLTQILEDAVSEHAPPMVGSRRIKLRYAHLGGANPPLIVIHGNQV
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEECCHH
EKVPKSYVRYLENTYRRVLKLVGTPIRIEFKGGENPYEGNKNTLTDRQVNKKRRMMSHHK
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KADKKRRDKR
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA