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The map label for this gene is trxB [H]

Identifier: 66044269

GI number: 66044269

Start: 1149858

End: 1150820

Strand: Direct

Name: trxB [H]

Synonym: Psyr_1016

Alternate gene names: 66044269

Gene position: 1149858-1150820 (Clockwise)

Preceding gene: 66044264

Following gene: 66044277

Centisome position: 18.87

GC content: 62.72

Gene sequence:

>963_bases
ATGTCAGACGTACGTCATTCCCGAGTGATCATTCTCGGTTCCGGCCCTGCCGGTTACAGCGCTGCGGTCTACGCCGCTCG
CGCCAACCTCAAGCCCCTGCTGATCACCGGCATGCAGGCTGGCGGCCAATTGACCACGACTACAGAAGTTGATAACTGGC
CAGGCGACCCGCACGGCCTGACCGGTCCTGCCCTGATGGAACGCATGCGTGAGCATGCCGAGCGTTTCGAGACTGAAATC
GTCTTCGACCACATCAATTCGGTTGATCTGGCCGGCAAGCCGTTCAGCCTGCAGGGCGATAGCGCGACCTACACCTGCGA
CGCCCTGATCATTGCCACCGGCGCCAGCGCCCGCTACCTGGGCCTGCCTTCAGAAGAAGCGTTCATGGGCAAGGGTGTTT
CTGCCTGCGCCACCTGCGACGGTTTCTTCTATCGCAACCGTGAAGTCGCGGTGGTCGGTGGGGGTAACACCGCGGTGGAA
GAGGCGCTGTATCTGGCCAACATCGCCAGCAAGGTGACCCTGGTTCACCGTCGCGAAACCTTCCGTGCCGAGAAGATCCT
GATCGACAAGCTGCACGCGCGTGTCGCCGAGGGCAAGATCGAACTCAAGCTCAACGCCACGCTGGACGAGGTCCTGGGTG
ACAACATGGGCGTGACCGGTGCGCGCCTGAAGAACAACGACGGCAGCAGCAGCGAGCTGAAAGTCGACGGCGTGTTCATC
GCGATCGGCCACACGCCGAACACCTCGTTGTTCGACGGCCAGCTGGCCTTGAAGGACGGTTACATGGTTGTGCAGGGTGG
CCGTGAAGGCAACGCCACAGCGACCAGCGTCGAAGGCGTATTCGCGGCCGGCGACGTGGCCGACCACGTGTATCGCCAGG
CCATTACCTCGGCCGGTGCCGGCTGCATGGCGGCACTCGATGTCGAGCGCTACCTGGACGGGCTGGCTGACGTATCGTTC
TGA

Upstream 100 bases:

>100_bases
GACCCGCCGAAGCAAATGACGCTTCCCCAAGCGTTTCGGTGGTCCTTTTTATCCAGCCGTCCCGACCGCGGCGTAAACGG
TCGGTCGATAGGAGTGTGTC

Downstream 100 bases:

>100_bases
TCGTTGCCGTCTGATTCACTTCGTGCCAATGCTTTGCATTGGCACGAAGTTCGCTGCGTTCTGCTGGATATATCTGCGCC
GCGCGACAAGGAGCAGCGGT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSDVRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDPHGLTGPALMERMREHAERFETEI
VFDHINSVDLAGKPFSLQGDSATYTCDALIIATGASARYLGLPSEEAFMGKGVSACATCDGFFYRNREVAVVGGGNTAVE
EALYLANIASKVTLVHRRETFRAEKILIDKLHARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSSSELKVDGVFI
AIGHTPNTSLFDGQLALKDGYMVVQGGREGNATATSVEGVFAAGDVADHVYRQAITSAGAGCMAALDVERYLDGLADVSF

Sequences:

>Translated_320_residues
MSDVRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDPHGLTGPALMERMREHAERFETEI
VFDHINSVDLAGKPFSLQGDSATYTCDALIIATGASARYLGLPSEEAFMGKGVSACATCDGFFYRNREVAVVGGGNTAVE
EALYLANIASKVTLVHRRETFRAEKILIDKLHARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSSSELKVDGVFI
AIGHTPNTSLFDGQLALKDGYMVVQGGREGNATATSVEGVFAAGDVADHVYRQAITSAGAGCMAALDVERYLDGLADVSF
>Mature_319_residues
SDVRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDPHGLTGPALMERMREHAERFETEIV
FDHINSVDLAGKPFSLQGDSATYTCDALIIATGASARYLGLPSEEAFMGKGVSACATCDGFFYRNREVAVVGGGNTAVEE
ALYLANIASKVTLVHRRETFRAEKILIDKLHARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSSSELKVDGVFIA
IGHTPNTSLFDGQLALKDGYMVVQGGREGNATATSVEGVFAAGDVADHVYRQAITSAGAGCMAALDVERYLDGLADVSF

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=72.1003134796238, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI87081763, Length=314, Percent_Identity=32.8025477707006, Blast_Score=138, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=47.6780185758514, Blast_Score=281, Evalue=9e-77,
Organism=Saccharomyces cerevisiae, GI6321898, Length=325, Percent_Identity=45.2307692307692, Blast_Score=268, Evalue=9e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33818; Mature: 33686

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDPHGL
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPALMERMREHAERFETEIVFDHINSVDLAGKPFSLQGDSATYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCCEEEEEEEEEEECCCEEEE
GLPSEEAFMGKGVSACATCDGFFYRNREVAVVGGGNTAVEEALYLANIASKVTLVHRRET
CCCCCHHHHCCCCCHHEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHEEEEEHHHH
FRAEKILIDKLHARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSSSELKVDGVFI
HHHHHHHHHHHHHHHHCCEEEEEECCCHHHHCCCCCCCCCEEEECCCCCCCEEEEEEEEE
AIGHTPNTSLFDGQLALKDGYMVVQGGREGNATATSVEGVFAAGDVADHVYRQAITSAGA
EEECCCCCCEECCEEEEECCEEEEECCCCCCCEEEEECCEEECCHHHHHHHHHHHHHCCC
GCMAALDVERYLDGLADVSF
CCEEHEEHHHHHHHHHCCCC
>Mature Secondary Structure 
SDVRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDPHGL
CCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPALMERMREHAERFETEIVFDHINSVDLAGKPFSLQGDSATYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCCEEEEEEEEEEECCCEEEE
GLPSEEAFMGKGVSACATCDGFFYRNREVAVVGGGNTAVEEALYLANIASKVTLVHRRET
CCCCCHHHHCCCCCHHEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHEEEEEHHHH
FRAEKILIDKLHARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSSSELKVDGVFI
HHHHHHHHHHHHHHHHCCEEEEEECCCHHHHCCCCCCCCCEEEECCCCCCCEEEEEEEEE
AIGHTPNTSLFDGQLALKDGYMVVQGGREGNATATSVEGVFAAGDVADHVYRQAITSAGA
EEECCCCCCEECCEEEEECCEEEEECCCCCCCEEEEECCEEECCHHHHHHHHHHHHHCCC
GCMAALDVERYLDGLADVSF
CCEEHEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]