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The map label for this gene is gpo [H]

Identifier: 66044263

GI number: 66044263

Start: 1144436

End: 1144924

Strand: Direct

Name: gpo [H]

Synonym: Psyr_1010

Alternate gene names: 66044263

Gene position: 1144436-1144924 (Clockwise)

Preceding gene: 66044262

Following gene: 66044264

Centisome position: 18.78

GC content: 55.62

Gene sequence:

>489_bases
ATGAGTGCTTTTCACGACATCAAATTGAAAGCGCTGGGTGGCCAGGAACTGCCGCTGGCGAATTTCAGAAAAAAAGTGGT
TCTGGTAGTCAACGTCGCGTCCAAATGCGGGCTGACACCGCAGTACGCGGCACTTGAAAACCTCTATCAGCAGTACAAGG
ACCAGGGCCTGGAGATACTGGGTCTGCCGTGCAACCAGTTTGCCGGGCAGGAACCGGGTACCGAGCAAGAGATCGCCGAA
TTTTGCCAACTCAACTATGGCGTGACGTTTACGCTGGGTGAAAAACTCGACGTCAACGGCCCCAACCGGCACTCGCTTTA
CCGTTTGCTGGCGGGCGAGGGTGCCGAGTTTCCCGGGGATATCACCTGGAACTTCGAAAAGTTTCTGGTTGGCAAGAACG
GCGGTGTAAGCGCACGTTTTTCTCCGCGTACTACTCCGGATGATCCTGCGGTGATCCAGGCCATCGAAAAGGCCCTGGCG
CAAAGCTGA

Upstream 100 bases:

>100_bases
CGCCCTGGCTGTTCTGCGATGACGACTTTCGTTACGCGTGCGGTCACGGTGCCTTTTTTCGGGTTGTAGCCTGGGGCGAC
TTGTTTCAAAAGGGGTTCTC

Downstream 100 bases:

>100_bases
TCGTAGAGCCGGGGTAGCATTTAGCATTCGCCCGGCTTTCTTGCGCGCTCGTCGCTTCTGAACTCAAATCAGCCAGATCA
ATAGTACTGGGCCGCCGCTG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSAFHDIKLKALGGQELPLANFRKKVVLVVNVASKCGLTPQYAALENLYQQYKDQGLEILGLPCNQFAGQEPGTEQEIAE
FCQLNYGVTFTLGEKLDVNGPNRHSLYRLLAGEGAEFPGDITWNFEKFLVGKNGGVSARFSPRTTPDDPAVIQAIEKALA
QS

Sequences:

>Translated_162_residues
MSAFHDIKLKALGGQELPLANFRKKVVLVVNVASKCGLTPQYAALENLYQQYKDQGLEILGLPCNQFAGQEPGTEQEIAE
FCQLNYGVTFTLGEKLDVNGPNRHSLYRLLAGEGAEFPGDITWNFEKFLVGKNGGVSARFSPRTTPDDPAVIQAIEKALA
QS
>Mature_161_residues
SAFHDIKLKALGGQELPLANFRKKVVLVVNVASKCGLTPQYAALENLYQQYKDQGLEILGLPCNQFAGQEPGTEQEIAEF
CQLNYGVTFTLGEKLDVNGPNRHSLYRLLAGEGAEFPGDITWNFEKFLVGKNGGVSARFSPRTTPDDPAVIQAIEKALAQ
S

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=148, Percent_Identity=39.8648648648649, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI90903240, Length=148, Percent_Identity=39.8648648648649, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI15618997, Length=159, Percent_Identity=35.2201257861635, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI192455698, Length=161, Percent_Identity=32.2981366459627, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI4557629, Length=165, Percent_Identity=36.969696969697, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=39.2307692307692, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI6006001, Length=154, Percent_Identity=39.6103896103896, Blast_Score=87, Evalue=5e-18,
Organism=Homo sapiens, GI32967607, Length=170, Percent_Identity=32.9411764705882, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI33186887, Length=148, Percent_Identity=37.8378378378378, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI41406084, Length=176, Percent_Identity=33.5227272727273, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1788003, Length=174, Percent_Identity=45.9770114942529, Blast_Score=162, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17535473, Length=161, Percent_Identity=47.2049689440994, Blast_Score=139, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17506887, Length=163, Percent_Identity=42.9447852760736, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71993584, Length=146, Percent_Identity=40.4109589041096, Blast_Score=115, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17550320, Length=179, Percent_Identity=35.195530726257, Blast_Score=106, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI193209493, Length=188, Percent_Identity=31.3829787234043, Blast_Score=99, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI193210707, Length=148, Percent_Identity=37.8378378378378, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71993573, Length=83, Percent_Identity=38.5542168674699, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71999642, Length=73, Percent_Identity=41.0958904109589, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=162, Percent_Identity=50.6172839506173, Blast_Score=168, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6322228, Length=163, Percent_Identity=50.3067484662577, Blast_Score=165, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322826, Length=163, Percent_Identity=43.558282208589, Blast_Score=129, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24656767, Length=163, Percent_Identity=41.7177914110429, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24656772, Length=163, Percent_Identity=41.1042944785276, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24656777, Length=163, Percent_Identity=41.7177914110429, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI85726443, Length=146, Percent_Identity=39.041095890411, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17702; Mature: 17571

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFHDIKLKALGGQELPLANFRKKVVLVVNVASKCGLTPQYAALENLYQQYKDQGLEIL
CCCCCCEEEEECCCCCCCHHHCCCEEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCEEE
GLPCNQFAGQEPGTEQEIAEFCQLNYGVTFTLGEKLDVNGPNRHSLYRLLAGEGAEFPGD
ECCCHHHCCCCCCCHHHHHHHHHCCCCEEEEECCEEECCCCCHHHHHHHHHCCCCCCCCC
ITWNFEKFLVGKNGGVSARFSPRTTPDDPAVIQAIEKALAQS
EEECCEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAFHDIKLKALGGQELPLANFRKKVVLVVNVASKCGLTPQYAALENLYQQYKDQGLEIL
CCCCCEEEEECCCCCCCHHHCCCEEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCEEE
GLPCNQFAGQEPGTEQEIAEFCQLNYGVTFTLGEKLDVNGPNRHSLYRLLAGEGAEFPGD
ECCCHHHCCCCCCCHHHHHHHHHCCCCEEEEECCEEECCCCCHHHHHHHHHCCCCCCCCC
ITWNFEKFLVGKNGGVSARFSPRTTPDDPAVIQAIEKALAQS
EEECCEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]