Click here to switch to the map view.

The map label for this gene is slyD [H]

Identifier: 66044262

GI number: 66044262

Start: 1143819

End: 1144304

Strand: Direct

Name: slyD [H]

Synonym: Psyr_1009

Alternate gene names: 66044262

Gene position: 1143819-1144304 (Clockwise)

Preceding gene: 66044258

Following gene: 66044263

Centisome position: 18.77

GC content: 59.26

Gene sequence:

>486_bases
ATGCCGATCGCCGCCAATAAGGCTGTCTCCATTGACTATACCCTGACCAACGACGCTGGTGAGGTCATCGACAGTTCTGC
CGGTGGTGCGCCGCTGGTTTACCTGCAAGGTGCAGGCAACATCATCCCGGGCTTGGAAAAGGCACTGGAAGGCAAGGAAG
TAGGCGAGCAGGTGAAAGTCGCCGTCGAGCCCGAAGACGCCTACGGCGAGTACTCGGCCGAACTGGTCAGCACCCTGAGC
AGCAGCATGTTCGAAGGCGTCGACAAGCTTGAAGTCGGCATGCAGTTTCACGCTTCCGGCCCGGATGGCGGCATGCAGAT
CGTGACCATCCGTGATCTGGATGGCGACGACGTCACTGTTGACGGCAACCATCCGCTCGCGGGTCAGCGCCTGAACTTCG
ACGTGAAGGTTGTGGCCATCCGTGATGCCAGTGAAGAAGAAATGGCTCACGGCCATGTTCACGGCGAAGGCGGTCATCAA
CACTGA

Upstream 100 bases:

>100_bases
CTTTCCAATCAGGGCCGTCCGTCAGAGTTGCGTTCGCTTTCGGGCGATTGCTTGGTTAAACTTGCCCGTTCTTCAATCTT
AAGCAAAAGGTCTTGTCCCC

Downstream 100 bases:

>100_bases
TTTGTGCTGCTAAGCTCAGGCACTGAAAAGGCGCCCTGGCTGTTCTGCGATGACGACTTTCGTTACGCGTGCGGTCACGG
TGCCTTTTTTCGGGTTGTAG

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MPIAANKAVSIDYTLTNDAGEVIDSSAGGAPLVYLQGAGNIIPGLEKALEGKEVGEQVKVAVEPEDAYGEYSAELVSTLS
SSMFEGVDKLEVGMQFHASGPDGGMQIVTIRDLDGDDVTVDGNHPLAGQRLNFDVKVVAIRDASEEEMAHGHVHGEGGHQ
H

Sequences:

>Translated_161_residues
MPIAANKAVSIDYTLTNDAGEVIDSSAGGAPLVYLQGAGNIIPGLEKALEGKEVGEQVKVAVEPEDAYGEYSAELVSTLS
SSMFEGVDKLEVGMQFHASGPDGGMQIVTIRDLDGDDVTVDGNHPLAGQRLNFDVKVVAIRDASEEEMAHGHVHGEGGHQ
H
>Mature_160_residues
PIAANKAVSIDYTLTNDAGEVIDSSAGGAPLVYLQGAGNIIPGLEKALEGKEVGEQVKVAVEPEDAYGEYSAELVSTLSS
SMFEGVDKLEVGMQFHASGPDGGMQIVTIRDLDGDDVTVDGNHPLAGQRLNFDVKVVAIRDASEEEMAHGHVHGEGGHQH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=149, Percent_Identity=49.6644295302013, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1786211, Length=144, Percent_Identity=34.7222222222222, Blast_Score=87, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16868; Mature: 16737

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAANKAVSIDYTLTNDAGEVIDSSAGGAPLVYLQGAGNIIPGLEKALEGKEVGEQVKV
CCCCCCCEEEEEEEEECCCHHHHCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCEEEE
AVEPEDAYGEYSAELVSTLSSSMFEGVDKLEVGMQFHASGPDGGMQIVTIRDLDGDDVTV
EECCCCCCCHHHHHHHHHHHHHHHCCHHHEEECEEEECCCCCCCEEEEEEEECCCCEEEE
DGNHPLAGQRLNFDVKVVAIRDASEEEMAHGHVHGEGGHQH
CCCCCCCCCEECCEEEEEEEECCCHHHHHCCEEECCCCCCC
>Mature Secondary Structure 
PIAANKAVSIDYTLTNDAGEVIDSSAGGAPLVYLQGAGNIIPGLEKALEGKEVGEQVKV
CCCCCCEEEEEEEEECCCHHHHCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCEEEE
AVEPEDAYGEYSAELVSTLSSSMFEGVDKLEVGMQFHASGPDGGMQIVTIRDLDGDDVTV
EECCCCCCCHHHHHHHHHHHHHHHCCHHHEEECEEEECCCCCCCEEEEEEEECCCCEEEE
DGNHPLAGQRLNFDVKVVAIRDASEEEMAHGHVHGEGGHQH
CCCCCCCCCEECCEEEEEEEECCCHHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]