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The map label for this gene is atoB [H]

Identifier: 66044079

GI number: 66044079

Start: 932388

End: 933566

Strand: Reverse

Name: atoB [H]

Synonym: Psyr_0824

Alternate gene names: 66044079

Gene position: 933566-932388 (Counterclockwise)

Preceding gene: 66044080

Following gene: 66044075

Centisome position: 15.32

GC content: 64.55

Gene sequence:

>1179_bases
ATGCACGACGTCGTTATCGTCGCCGCCACGCGTACCGCTGTGGGCAGTTTTCAGGGCTCACTGGCCTCTGTCGCCGCAGT
CGACCTCGGCGCAGCGGTCATTCGTCAACTGCTTGCCCGCACCGGCGTGGACGGCGCGCAGGTCGATGAGGTCATCATGG
GTCAGGTGCTGACCGCAGGCGCTGGTCAGAACCCCGCGCGGCAGGCAGCCATCAAGGCCGGCCTGCCCTTCTCGGTGCCG
GCCATGACCCTGAACAAGGTCTGCGGCTCTGGCCTCAAGGCCCTGCACCTGGCGACCCAGGCGATTCGTTGCGGCGACGC
CGAGATCATCATCGCCGGTGGCCAGGAAAACATGAGCCTGTCCAATTACGTGCTGCCGGGCGCGCGCACCGGATTGCGCA
TGGGCCACGCCAGCATGGTCGATACGATGATCACTGACGGCCTGTGGGATGCATTCAATGATTACCACATGGGCATCACT
GCCGAGAACCTCGCGCAGCAGTACGACATCAGCCGTGAAGCCCAGGATGAGTTCGCCGCTTTGTCTCAGCAGAAGGCGAT
GGCTGCGATTGAAGCCGGACGCTTCGTCGATGAGATCACCCCGATCCTGATCCCGCAGCGCAAGGGTGATCCGCTGTCCT
TTGCAACAGACGAGCAGCCCCGCGCCGGCACCACTGCCGAGACGCTGGCCAAGCTCAAGCCCGCGTTCAAAAAGGACGGT
ACGGTCACCGCCGGCAATGCCTCTTCGCTGAACGACGGAGCGGCCGCCGTGATGCTGATGAGTACCGCTAAAGCCGAGCA
ACTGGGCCTGCCGGTGCTGGCCCGCATTGCCGGGTATGCCAACGCCGGTGTCGACCCGGCCATCATGGGCATCGGGCCGG
TCAGTGCCACACGTCGCTGCCTGGACAAGGCTGGCTGGTCGCTGGCCGAGCTGGACCTGATCGAAGCCAACGAAGCCTTC
GCTGCACAGTCCCTGTCGGTCGGCAAGGCGCTGGGGCTGGATCCGCAAAAGCTCAACGTGAATGGTGGCGCTATCGCCCT
TGGTCACCCGATTGGCGCGTCGGGCTGCCGCGTGCTGGTGACACTGCTGCACGAGATGATCAGGCGCGATGTGAAGAAGG
GCCTGGCCACGCTGTGCATCGGTGGTGGTCAGGGGGTTGCTCTGGCACTCGAACGCTAG

Upstream 100 bases:

>100_bases
ATGAAGGTTTTCGGCAAACCGTGACCGGGCGGTTCACGGTTGGAACCTGCCTGCCTATCTGTGCCACCATGAGCACTCAA
TAACAATGAGGATCAGCACC

Downstream 100 bases:

>100_bases
AGCAGGAAGAAGGCGCGGGGCAGCCCGCGCCTTGCATCATCAGGCGGCTGCGGGCGCCACTTCCATGTCAGCGGGCTCCG
GGCGCTTGATCAGCGCGTAG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MHDVVIVAATRTAVGSFQGSLASVAAVDLGAAVIRQLLARTGVDGAQVDEVIMGQVLTAGAGQNPARQAAIKAGLPFSVP
AMTLNKVCGSGLKALHLATQAIRCGDAEIIIAGGQENMSLSNYVLPGARTGLRMGHASMVDTMITDGLWDAFNDYHMGIT
AENLAQQYDISREAQDEFAALSQQKAMAAIEAGRFVDEITPILIPQRKGDPLSFATDEQPRAGTTAETLAKLKPAFKKDG
TVTAGNASSLNDGAAAVMLMSTAKAEQLGLPVLARIAGYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEANEAF
AAQSLSVGKALGLDPQKLNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDVKKGLATLCIGGGQGVALALER

Sequences:

>Translated_392_residues
MHDVVIVAATRTAVGSFQGSLASVAAVDLGAAVIRQLLARTGVDGAQVDEVIMGQVLTAGAGQNPARQAAIKAGLPFSVP
AMTLNKVCGSGLKALHLATQAIRCGDAEIIIAGGQENMSLSNYVLPGARTGLRMGHASMVDTMITDGLWDAFNDYHMGIT
AENLAQQYDISREAQDEFAALSQQKAMAAIEAGRFVDEITPILIPQRKGDPLSFATDEQPRAGTTAETLAKLKPAFKKDG
TVTAGNASSLNDGAAAVMLMSTAKAEQLGLPVLARIAGYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEANEAF
AAQSLSVGKALGLDPQKLNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDVKKGLATLCIGGGQGVALALER
>Mature_392_residues
MHDVVIVAATRTAVGSFQGSLASVAAVDLGAAVIRQLLARTGVDGAQVDEVIMGQVLTAGAGQNPARQAAIKAGLPFSVP
AMTLNKVCGSGLKALHLATQAIRCGDAEIIIAGGQENMSLSNYVLPGARTGLRMGHASMVDTMITDGLWDAFNDYHMGIT
AENLAQQYDISREAQDEFAALSQQKAMAAIEAGRFVDEITPILIPQRKGDPLSFATDEQPRAGTTAETLAKLKPAFKKDG
TVTAGNASSLNDGAAAVMLMSTAKAEQLGLPVLARIAGYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEANEAF
AAQSLSVGKALGLDPQKLNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDVKKGLATLCIGGGQGVALALER

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=391, Percent_Identity=53.1969309462916, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI167614485, Length=396, Percent_Identity=44.6969696969697, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI4557237, Length=393, Percent_Identity=41.9847328244275, Blast_Score=304, Evalue=1e-82,
Organism=Homo sapiens, GI4501853, Length=395, Percent_Identity=42.5316455696203, Blast_Score=268, Evalue=7e-72,
Organism=Homo sapiens, GI4504327, Length=426, Percent_Identity=31.6901408450704, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI194353979, Length=248, Percent_Identity=34.6774193548387, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI87082165, Length=392, Percent_Identity=67.3469387755102, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=60.0508905852417, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1787663, Length=401, Percent_Identity=45.3865336658354, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI48994986, Length=412, Percent_Identity=44.9029126213592, Blast_Score=282, Evalue=2e-77,
Organism=Escherichia coli, GI1788683, Length=427, Percent_Identity=33.2552693208431, Blast_Score=186, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI133906874, Length=390, Percent_Identity=46.1538461538462, Blast_Score=334, Evalue=5e-92,
Organism=Caenorhabditis elegans, GI25147385, Length=387, Percent_Identity=38.5012919896641, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17535921, Length=393, Percent_Identity=36.6412213740458, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17551802, Length=426, Percent_Identity=31.4553990610329, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17535917, Length=392, Percent_Identity=32.9081632653061, Blast_Score=167, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6325229, Length=395, Percent_Identity=43.2911392405063, Blast_Score=301, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6322031, Length=392, Percent_Identity=40.8163265306122, Blast_Score=256, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24655093, Length=392, Percent_Identity=57.3979591836735, Blast_Score=446, Evalue=1e-125,
Organism=Drosophila melanogaster, GI17648125, Length=390, Percent_Identity=45.3846153846154, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24640423, Length=391, Percent_Identity=42.1994884910486, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI17137578, Length=426, Percent_Identity=30.9859154929577, Blast_Score=169, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40415; Mature: 40415

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDVVIVAATRTAVGSFQGSLASVAAVDLGAAVIRQLLARTGVDGAQVDEVIMGQVLTAG
CCCEEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
AGQNPARQAAIKAGLPFSVPAMTLNKVCGSGLKALHLATQAIRCGDAEIIIAGGQENMSL
CCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCC
SNYVLPGARTGLRMGHASMVDTMITDGLWDAFNDYHMGITAENLAQQYDISREAQDEFAA
CCEECCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHH
LSQQKAMAAIEAGRFVDEITPILIPQRKGDPLSFATDEQPRAGTTAETLAKLKPAFKKDG
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
TVTAGNASSLNDGAAAVMLMSTAKAEQLGLPVLARIAGYANAGVDPAIMGIGPVSATRRC
CEECCCCCCCCCCHHEEEHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
LDKAGWSLAELDLIEANEAFAAQSLSVGKALGLDPQKLNVNGGAIALGHPIGASGCRVLV
HHHCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCCCHHHHHHH
TLLHEMIRRDVKKGLATLCIGGGQGVALALER
HHHHHHHHHHHHHCHHEEEECCCCCEEEEECC
>Mature Secondary Structure
MHDVVIVAATRTAVGSFQGSLASVAAVDLGAAVIRQLLARTGVDGAQVDEVIMGQVLTAG
CCCEEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
AGQNPARQAAIKAGLPFSVPAMTLNKVCGSGLKALHLATQAIRCGDAEIIIAGGQENMSL
CCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCC
SNYVLPGARTGLRMGHASMVDTMITDGLWDAFNDYHMGITAENLAQQYDISREAQDEFAA
CCEECCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHH
LSQQKAMAAIEAGRFVDEITPILIPQRKGDPLSFATDEQPRAGTTAETLAKLKPAFKKDG
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
TVTAGNASSLNDGAAAVMLMSTAKAEQLGLPVLARIAGYANAGVDPAIMGIGPVSATRRC
CEECCCCCCCCCCHHEEEHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
LDKAGWSLAELDLIEANEAFAAQSLSVGKALGLDPQKLNVNGGAIALGHPIGASGCRVLV
HHHCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCCCHHHHHHH
TLLHEMIRRDVKKGLATLCIGGGQGVALALER
HHHHHHHHHHHHHCHHEEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]