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The map label for this gene is gntP [H]

Identifier: 66043684

GI number: 66043684

Start: 455430

End: 456779

Strand: Reverse

Name: gntP [H]

Synonym: Psyr_0417

Alternate gene names: 66043684

Gene position: 456779-455430 (Counterclockwise)

Preceding gene: 66043685

Following gene: 66043683

Centisome position: 7.5

GC content: 61.7

Gene sequence:

>1350_bases
ATGTCGCCGTCACCCGGTATTTCGCTATTGGTCTACGCCGCTGTCGCCATCATCGCCTTGATCGTGCTGATCGCGCGTTA
CCGCCTCAATCCGTTTATCGTCATCACGCTTGTTTCGGTCGGTCTGGCACTGGTTGCGGGAATGCCGGCCAGTGGCGTGG
TCGCCTCTTATGAAGCGGGGGTTGGCAAAACGCTGGGGCATATCGCGCTGGTCGTGGCGCTGGGCACCATGCTCGGCAAG
ATGATGGCCGAGTCTGGCGGCGCCGAGCAGGTGGCGCGCACCCTGATCGATCGCTTTGGCGAACGTAACGCGCACTGGGC
CATGGTCTGCATTGCGTTTCTGGTGGGCTTGCCACTGTTTTTCGAAGTGGGCTTTGTGCTGCTGGTGCCGATTGCCTTTA
CCGTAGCGCGCCGTGTCGGGGTGTCGATTCTGATGGTCGGCCTGCCGATGGTCGCCGGTCTTTCGGTGGTGCATGCGCTG
GTGCCGCCGCACCCTGCTGCGATGCTCGCGGTGCAGGCGTATCAGGCGTCGGTAGGACAAACGCTGTTCTACGCCATTCT
GATCGGCATCCCCACGGCCATCATCGCCGGTCCGGTGTATGCCAAATTCATTGTCCCGCGCATCCACCTGCCGGCTGAAA
ACCCTTTGGCCAAGCAGTTTCTCGACCGCGAGCCACGCCAGAAGCTGCCCAGCTTCGGCCTGACCATGGCCACGATTCTG
CTGCCGGTGGTGCTGATGCTGCTGGGTGGCTGGGCCAACCTGATCAGTACACCGGGTAGCGCGTTCAACAGCTTTCTGCT
GTTCATCGGTAACTCGGTGATTGCCCTGCTGCTGGCCACCCTGCTGAGCTTCTGGACGCTGGGCATCGCGCAGGGCTTCA
ACCGCGACTCTATCCTGAAATTCACCAACGAGTGCCTGGCACCGACCGCCAGCATCACGTTGCTGGTAGGTGCCGGTGGC
GGCTTGAACCGCATTCTGATCGACAGCGGCGTGACCAATGAGATCGTCGGCCTGGCGCAGGACTTTCATCTGTCGCCCCT
GCTGATGGGCTGGCTGTTCGCGGCACTGATGCGCGTTGCCACCGGCTCGGCGACGGTGGCGATGACCACGGCATCGGGCA
TCGTTGCACCTGTGGCGATGGGGCTGGGTTATCCACACCCCGAACTGCTGGTGCTGGCGACGGGTGCAGGCTCGGTGATC
TTTTCCCACGTCAACGACGGTGGGTTCTGGCTTATCAAGGAGTATTTCAACATGACCGTTGCGCAAACGTTCAAGACCTG
GACGGTCTTGGAGACGCTGATTTCCGTCGTCGCTTTCGCCCTGACGCTGGGCCTGGCGCAGGTGCTTTGA

Upstream 100 bases:

>100_bases
TGCGTCATCCCTGCCGAGTACTCCCGAGTCGCCTTCAGGCTGACAGCTTCAGCTGTTGGTGTTGCGCCCTCGCCTACCCA
CTTTGCAAGGAATCGTCGCT

Downstream 100 bases:

>100_bases
GTGGACATTCTGTACCAGATACGTGCCCGTCAGGATTCCTTCAGTGCGGGAGAAGGCCGAATCGCCAGGCTGTTGCTCAG
CGATATCGCCTTCGCGGCCA

Product: gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSPSPGISLLVYAAVAIIALIVLIARYRLNPFIVITLVSVGLALVAGMPASGVVASYEAGVGKTLGHIALVVALGTMLGK
MMAESGGAEQVARTLIDRFGERNAHWAMVCIAFLVGLPLFFEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHAL
VPPHPAAMLAVQAYQASVGQTLFYAILIGIPTAIIAGPVYAKFIVPRIHLPAENPLAKQFLDREPRQKLPSFGLTMATIL
LPVVLMLLGGWANLISTPGSAFNSFLLFIGNSVIALLLATLLSFWTLGIAQGFNRDSILKFTNECLAPTASITLLVGAGG
GLNRILIDSGVTNEIVGLAQDFHLSPLLMGWLFAALMRVATGSATVAMTTASGIVAPVAMGLGYPHPELLVLATGAGSVI
FSHVNDGGFWLIKEYFNMTVAQTFKTWTVLETLISVVAFALTLGLAQVL

Sequences:

>Translated_449_residues
MSPSPGISLLVYAAVAIIALIVLIARYRLNPFIVITLVSVGLALVAGMPASGVVASYEAGVGKTLGHIALVVALGTMLGK
MMAESGGAEQVARTLIDRFGERNAHWAMVCIAFLVGLPLFFEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHAL
VPPHPAAMLAVQAYQASVGQTLFYAILIGIPTAIIAGPVYAKFIVPRIHLPAENPLAKQFLDREPRQKLPSFGLTMATIL
LPVVLMLLGGWANLISTPGSAFNSFLLFIGNSVIALLLATLLSFWTLGIAQGFNRDSILKFTNECLAPTASITLLVGAGG
GLNRILIDSGVTNEIVGLAQDFHLSPLLMGWLFAALMRVATGSATVAMTTASGIVAPVAMGLGYPHPELLVLATGAGSVI
FSHVNDGGFWLIKEYFNMTVAQTFKTWTVLETLISVVAFALTLGLAQVL
>Mature_448_residues
SPSPGISLLVYAAVAIIALIVLIARYRLNPFIVITLVSVGLALVAGMPASGVVASYEAGVGKTLGHIALVVALGTMLGKM
MAESGGAEQVARTLIDRFGERNAHWAMVCIAFLVGLPLFFEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHALV
PPHPAAMLAVQAYQASVGQTLFYAILIGIPTAIIAGPVYAKFIVPRIHLPAENPLAKQFLDREPRQKLPSFGLTMATILL
PVVLMLLGGWANLISTPGSAFNSFLLFIGNSVIALLLATLLSFWTLGIAQGFNRDSILKFTNECLAPTASITLLVGAGGG
LNRILIDSGVTNEIVGLAQDFHLSPLLMGWLFAALMRVATGSATVAMTTASGIVAPVAMGLGYPHPELLVLATGAGSVIF
SHVNDGGFWLIKEYFNMTVAQTFKTWTVLETLISVVAFALTLGLAQVL

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=429, Percent_Identity=45.2214452214452, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1790716, Length=440, Percent_Identity=40, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI2367370, Length=418, Percent_Identity=40.1913875598086, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1788707, Length=430, Percent_Identity=37.2093023255814, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1790776, Length=435, Percent_Identity=33.7931034482759, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI48994939, Length=433, Percent_Identity=35.5658198614319, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1789097, Length=446, Percent_Identity=33.4080717488789, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47139; Mature: 47008

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SPSPGISLLVYAAVAIIALIVLIARYRLNPFIVITLVSVGLALVAGMPASGVVASYEAG
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCC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HHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA