Click here to switch to the map view.

The map label for this gene is cynT [H]

Identifier: 66043558

GI number: 66043558

Start: 306535

End: 307275

Strand: Reverse

Name: cynT [H]

Synonym: Psyr_0288

Alternate gene names: 66043558

Gene position: 307275-306535 (Counterclockwise)

Preceding gene: 66043559

Following gene: 66043557

Centisome position: 5.04

GC content: 58.57

Gene sequence:

>741_bases
ATGACAGACATCGGTAAACAGCATTCGGCTACGTCGTCCAGCACATCAAGCCATTCAGACAGCGCCGACGTAGCGTTGAA
ACATATCGTCGATGGCTTTGTACATTTCCGTAAAGAGGTCTTCCCCCAGCAGGAAGAACTGTTCAAGAAGCTGGCGACCG
CCCAGTCGCCACGGGCCATGTTCATCACCTGCGCCGACTCGCGCATCGTGCCCGAATTGATTACCCAAAGCTCCCCGGGC
GACCTGTTCGTCACGCGTAACGTCGGCAACGTCGTACCGCCGTATGGCCAGATGAACGGCGGCGTGTCCACCGCTCTGGA
ATACGCAGTGGTTGCACTGGGCGTGCAGCACATCATCGTTTGCGGACACTCTGACTGCGGCGCCATGCGCGCAGTGCTCA
ACCCCGACAGCCTGGACAAGATGCCTACGGTAAAAGCCTGGTTGCGCCATGCCGAGGTTGCCCGCACGGTGGTCGAGCAG
AACTGCAGCTGCAGCGGCGAACTGGAAACCATGCAGGTCCTGACTCAGGAAAACGTGATTTCCCAGTTGCAACACCTGCG
CACCCACCCTTCGGTCGCAGCGAAAATGGCCAGCGGCCAATTGTTCATTCATGGCTGGGTCTACAGCATCGAAACCAGCG
AGATCCTGGCTTATGACGCCGAGCTCGATCGTTTCATACCGCTCGACGGTACGGGACCGACGCCGATGGCTTCACCGAAA
GCACGCTTTTCAGCCGACTGA

Upstream 100 bases:

>100_bases
CAAGGGATTTGTTCGTGATGCCCTTCAGAGAGGGATCACATCCGGCTCTGGTCAAACAGGCATGAAGAATCCACATCAAT
TCGTCAGAGAGGATGAAGAC

Downstream 100 bases:

>100_bases
TCACCAGTCCGACTGACGGCAAGCCCTTCTTTATCAGCTGATGGCGGCTGCGCAGGATGCGCGTCGCCCGTCTTGCCTCG
TCTGAAGAATCCCGGAGAAG

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTDIGKQHSATSSSTSSHSDSADVALKHIVDGFVHFRKEVFPQQEELFKKLATAQSPRAMFITCADSRIVPELITQSSPG
DLFVTRNVGNVVPPYGQMNGGVSTALEYAVVALGVQHIIVCGHSDCGAMRAVLNPDSLDKMPTVKAWLRHAEVARTVVEQ
NCSCSGELETMQVLTQENVISQLQHLRTHPSVAAKMASGQLFIHGWVYSIETSEILAYDAELDRFIPLDGTGPTPMASPK
ARFSAD

Sequences:

>Translated_246_residues
MTDIGKQHSATSSSTSSHSDSADVALKHIVDGFVHFRKEVFPQQEELFKKLATAQSPRAMFITCADSRIVPELITQSSPG
DLFVTRNVGNVVPPYGQMNGGVSTALEYAVVALGVQHIIVCGHSDCGAMRAVLNPDSLDKMPTVKAWLRHAEVARTVVEQ
NCSCSGELETMQVLTQENVISQLQHLRTHPSVAAKMASGQLFIHGWVYSIETSEILAYDAELDRFIPLDGTGPTPMASPK
ARFSAD
>Mature_245_residues
TDIGKQHSATSSSTSSHSDSADVALKHIVDGFVHFRKEVFPQQEELFKKLATAQSPRAMFITCADSRIVPELITQSSPGD
LFVTRNVGNVVPPYGQMNGGVSTALEYAVVALGVQHIIVCGHSDCGAMRAVLNPDSLDKMPTVKAWLRHAEVARTVVEQN
CSCSGELETMQVLTQENVISQLQHLRTHPSVAAKMASGQLFIHGWVYSIETSEILAYDAELDRFIPLDGTGPTPMASPKA
RFSAD

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=203, Percent_Identity=52.2167487684729, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1786318, Length=180, Percent_Identity=35.5555555555556, Blast_Score=101, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25147564, Length=254, Percent_Identity=30.7086614173228, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI115532990, Length=244, Percent_Identity=28.2786885245902, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6324292, Length=166, Percent_Identity=28.3132530120482, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24645213, Length=255, Percent_Identity=26.6666666666667, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26681; Mature: 26549

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIGKQHSATSSSTSSHSDSADVALKHIVDGFVHFRKEVFPQQEELFKKLATAQSPRAM
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEE
FITCADSRIVPELITQSSPGDLFVTRNVGNVVPPYGQMNGGVSTALEYAVVALGVQHIIV
EEEECCCCHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEE
CGHSDCGAMRAVLNPDSLDKMPTVKAWLRHAEVARTVVEQNCSCSGELETMQVLTQENVI
ECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SQLQHLRTHPSVAAKMASGQLFIHGWVYSIETSEILAYDAELDRFIPLDGTGPTPMASPK
HHHHHHHCCHHHHHHHCCCEEEEEEEEEEEECCHHEEECCCCCCEECCCCCCCCCCCCCC
ARFSAD
CCCCCC
>Mature Secondary Structure 
TDIGKQHSATSSSTSSHSDSADVALKHIVDGFVHFRKEVFPQQEELFKKLATAQSPRAM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEE
FITCADSRIVPELITQSSPGDLFVTRNVGNVVPPYGQMNGGVSTALEYAVVALGVQHIIV
EEEECCCCHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEE
CGHSDCGAMRAVLNPDSLDKMPTVKAWLRHAEVARTVVEQNCSCSGELETMQVLTQENVI
ECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SQLQHLRTHPSVAAKMASGQLFIHGWVYSIETSEILAYDAELDRFIPLDGTGPTPMASPK
HHHHHHHCCHHHHHHHCCCEEEEEEEEEEEECCHHEEECCCCCCEECCCCCCCCCCCCCC
ARFSAD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]