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The map label for this gene is ompR [H]

Identifier: 66043528

GI number: 66043528

Start: 274133

End: 274873

Strand: Direct

Name: ompR [H]

Synonym: Psyr_0258

Alternate gene names: 66043528

Gene position: 274133-274873 (Clockwise)

Preceding gene: 66043524

Following gene: 66043529

Centisome position: 4.5

GC content: 61.0

Gene sequence:

>741_bases
ATGAGCAGCACCGCACAAAATGCCGAAGGCGAAAAAATCCTTATTGTCGATGACGATCCGGGGCTGAGCAGTCTCCTGGA
ACGTTTTTTCACCAGCAAGGGCTATCGTGCCCGCGCCGTGGCAAATGTGGAACAAATGGACCGGCTGCTGGCCCGTGAGG
TTTTCAACCTCGTGGTGCTGGACCTGATGCTGCCCGGCGAAGACGGCCTTTCAGCCTGTCGTCGTCTGCGTGCCGCGAAC
AATCAGGTGCCGATTATCATGCTGACCGCCAAGGGCGATGAGCTGAGCCGCATCAAGGGGCTCGAACTGGGTGCTGATGA
TTATCTGGCCAAGCCGTTCAACCCGGACGAGCTGATGGCGCGGGTCAAGGCGGTGTTGCGTCGTCAGGCGGCACCGGTGC
CCGGCGCACCCGGCAGCGAAGACGAGTCTGTCAGTTTCGGTGACTACGTGCTGTCTCTGGCAACCCGCGAGCTCAAGCGC
GGTGAAGAAGTGCACATGCTCACTACCGGGGAGTTCGCGGTACTGAAAGCGCTGGTCATGCACGCTCGCGAGCCGCTGAC
CCGCGACAAACTGATGAACCTGGCGCGTGGCCGGGAGTGGGATGCGCTGGAACGATCCATCGACGTACAGATCTCCCGTC
TGCGTCGCCTGATCGAACCGGACCCTTCCAAGCCCCGTTATATCCAGACGGTCTGGGGCGTGGGCTATGTATTCGTTCCG
GACGGTGCCGGAAGTCGCTGA

Upstream 100 bases:

>100_bases
CAGGCACAAGTGTCGCCTCCAGTAAAATCTGCTAACAATGCACAAGGTGCGCATCACCGCAGCTACGCCATAATGCGCCC
CGAGATCAGAGGAGCATCCG

Downstream 100 bases:

>100_bases
TAACCCGGTTGTCGGCACAGACATCCGTCATTGCTGCCAGTTACGTCGATAATCTTTTACAGGTTTATCGACGTACTGGT
TTTTTGCGTTCGTCCATCGG

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSSTAQNAEGEKILIVDDDPGLSSLLERFFTSKGYRARAVANVEQMDRLLAREVFNLVVLDLMLPGEDGLSACRRLRAAN
NQVPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMARVKAVLRRQAAPVPGAPGSEDESVSFGDYVLSLATRELKR
GEEVHMLTTGEFAVLKALVMHAREPLTRDKLMNLARGREWDALERSIDVQISRLRRLIEPDPSKPRYIQTVWGVGYVFVP
DGAGSR

Sequences:

>Translated_246_residues
MSSTAQNAEGEKILIVDDDPGLSSLLERFFTSKGYRARAVANVEQMDRLLAREVFNLVVLDLMLPGEDGLSACRRLRAAN
NQVPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMARVKAVLRRQAAPVPGAPGSEDESVSFGDYVLSLATRELKR
GEEVHMLTTGEFAVLKALVMHAREPLTRDKLMNLARGREWDALERSIDVQISRLRRLIEPDPSKPRYIQTVWGVGYVFVP
DGAGSR
>Mature_245_residues
SSTAQNAEGEKILIVDDDPGLSSLLERFFTSKGYRARAVANVEQMDRLLAREVFNLVVLDLMLPGEDGLSACRRLRAANN
QVPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMARVKAVLRRQAAPVPGAPGSEDESVSFGDYVLSLATRELKRG
EEVHMLTTGEFAVLKALVMHAREPLTRDKLMNLARGREWDALERSIDVQISRLRRLIEPDPSKPRYIQTVWGVGYVFVPD
GAGSR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=67.9324894514768, Blast_Score=338, Evalue=2e-94,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.9310344827586, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1788394, Length=246, Percent_Identity=34.1463414634146, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=32.7510917030568, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=34.468085106383, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.6206896551724, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=37.7682403433476, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=36.3247863247863, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=35.0649350649351, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.0512820512821, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=31.6017316017316, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=32.4561403508772, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790860, Length=235, Percent_Identity=31.9148936170213, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=30.5676855895196, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=31.0924369747899, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=30.6306306306306, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=29.8245614035088, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27291; Mature: 27160

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTAQNAEGEKILIVDDDPGLSSLLERFFTSKGYRARAVANVEQMDRLLAREVFNLVVL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHH
DLMLPGEDGLSACRRLRAANNQVPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMA
HHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCCCCCHHCCCCCCHHHHHH
RVKAVLRRQAAPVPGAPGSEDESVSFGDYVLSLATRELKRGEEVHMLTTGEFAVLKALVM
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHH
HAREPLTRDKLMNLARGREWDALERSIDVQISRLRRLIEPDPSKPRYIQTVWGVGYVFVP
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCEEEEC
DGAGSR
CCCCCC
>Mature Secondary Structure 
SSTAQNAEGEKILIVDDDPGLSSLLERFFTSKGYRARAVANVEQMDRLLAREVFNLVVL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHH
DLMLPGEDGLSACRRLRAANNQVPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMA
HHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCCCCCHHCCCCCCHHHHHH
RVKAVLRRQAAPVPGAPGSEDESVSFGDYVLSLATRELKRGEEVHMLTTGEFAVLKALVM
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHH
HAREPLTRDKLMNLARGREWDALERSIDVQISRLRRLIEPDPSKPRYIQTVWGVGYVFVP
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCEEEEC
DGAGSR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]