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The map label for this gene is dppA [H]

Identifier: 66043493

GI number: 66043493

Start: 237260

End: 238846

Strand: Reverse

Name: dppA [H]

Synonym: Psyr_0223

Alternate gene names: 66043493

Gene position: 238846-237260 (Counterclockwise)

Preceding gene: 66043496

Following gene: 66043491

Centisome position: 3.92

GC content: 59.23

Gene sequence:

>1587_bases
ATGCGCCTAGCTGCACTCCCTTTTTTACTCGTTCCACTCCTGCTTCCCGTCGCTGCCCAGGCATCGAACCTTGTGGTCTG
CACCGAAGCCAGCCCCGAGGGCTTCGACGTTGTACAGTACAACTCGCTGACCACCACCAACGCATCGGCCGACGTGCTGA
TGAACCGCCTTGTAGACTTCGATGCCAAGAGCGGCAAGCTGGTGCCGAGCCTGGCAGATAGCTGGACCGTGTCCAAAGAC
GGCCTGACGTACGACTTCAAGCTGCACCCCGGAGTGAAATTCCACACCACCGACTATTTCAAGCCGACTCGCGAGCTGAG
CGCGGATGACGTGCTGTTCAGCTTCCAGCGCATGCTCGACCCGCAGAACCCGTGGCACAAGATCGCCCAGAGCGGCTTCC
CGCATGCGCAGTCCATGCAGCTGCCCGCGTTGATCAAGAGCATCGAAGCGCCTGATGCACACACCGTGCGCTTCACGCTC
AACCATGCGGACTCGACCTTCCTGGCCACGCTGAGCATGGGTTTCGCCTCCATCTATTCAGCCGAATATACTGCGCAGCT
GTTGAAAGCGGGTACGCCGGAGAAACTCAACAGCCAGCCGATCGGCACCGGGCCGTTCGTGTTCAAGCGCTTCCAGAAAG
ATGCCGTGGTGCGCTATGAGGCGTTCGACGATTACTTCGCCGGCAAATCTGATATCGACACATTGGTGTACGCCATCACC
CCGGACGCCAATGTGCGCCTGCAGAAAATCCGTCAGGACGAATGCCAGATAGCGCTCTCGCCCAAGCCCCTGGATATTCA
GGCAGCCAGCAAGGACGACTCGCTCAAGGTGGAGAAAACTGAAGCGTTCATGACCGCGTTTGTCGCGATCAACAGCCAGC
ACCCGCCGTTCGACAAGCCGGAAGTTCGCCAGGCCATCAATCTGGCGTTCGACAGGGACAATTACCTGAAAGCCGTGTTC
GAAGGCACCGCTGAAAAGGCCAACGGCCCTTACCCGCCCAACACCTGGAGTTACGCCAAGGACCTGCCCGGCTATCAGCA
CGATGTTGCCAAGGCCAAGGCGCTGCTGGCCAAGGCCGGTGTGAAAGAGGGCTTCAAGACCACTATCTGGACACGACCTT
CCGGGAGCCTGCTGAATCCGAACCCGAGCCTGGGTGCTCAATTGCTGCAGGCTGACTTGAAACAGATCGGCATCAATGCC
GAGATCAAGATCATTGAATGGGGCGAGCTGATTCGCCGCGCAAAGGCTGGCGAGCATGACCTGCTGTTCATGGGCTGGGC
GGGCGACAATGGCGACCCGGATAACTTCCTGACCCCGCAGTTCTCGTGTGCGGCCGTGCAATCGGGCACCAACTTCGCCC
GCTATTGCGACAAGACACTGGACAAGCTGATCGCAGACGGTAAATCAGTCAGTGATCAGGGCGAACGCAGCAAGCTGTAT
CACCAGGCCCAGCAGCAGATTCAACAGCAGGCACTGTGGATCCCCCTCGCCCACCCGACAGCTGCTGCACTGGTGCGCAA
GGACGTCACTGGCTATCAGGTCAGCCCGTTCGGCCGGCAGGATTTCTACAAGGTGCAGGTCAAGTAA

Upstream 100 bases:

>100_bases
CGCTCCATGACGATTGTTCTGCGCCAGTACATGGTCTAGGGTTAGTCCCTCACCAGACTGCGCCGGCAGATGGGGCCCTT
TCTGAACAGGAAATAACGCC

Downstream 100 bases:

>100_bases
GTCGCCAGACTGACCTCGGCCTCTCTGTGTGATGGCGTGCCAATGCCTGCTGCATTGGCACGCCCCGTCTGAAGACCGGA
CGCGGAGCGTGAGAACGATA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MRLAALPFLLVPLLLPVAAQASNLVVCTEASPEGFDVVQYNSLTTTNASADVLMNRLVDFDAKSGKLVPSLADSWTVSKD
GLTYDFKLHPGVKFHTTDYFKPTRELSADDVLFSFQRMLDPQNPWHKIAQSGFPHAQSMQLPALIKSIEAPDAHTVRFTL
NHADSTFLATLSMGFASIYSAEYTAQLLKAGTPEKLNSQPIGTGPFVFKRFQKDAVVRYEAFDDYFAGKSDIDTLVYAIT
PDANVRLQKIRQDECQIALSPKPLDIQAASKDDSLKVEKTEAFMTAFVAINSQHPPFDKPEVRQAINLAFDRDNYLKAVF
EGTAEKANGPYPPNTWSYAKDLPGYQHDVAKAKALLAKAGVKEGFKTTIWTRPSGSLLNPNPSLGAQLLQADLKQIGINA
EIKIIEWGELIRRAKAGEHDLLFMGWAGDNGDPDNFLTPQFSCAAVQSGTNFARYCDKTLDKLIADGKSVSDQGERSKLY
HQAQQQIQQQALWIPLAHPTAAALVRKDVTGYQVSPFGRQDFYKVQVK

Sequences:

>Translated_528_residues
MRLAALPFLLVPLLLPVAAQASNLVVCTEASPEGFDVVQYNSLTTTNASADVLMNRLVDFDAKSGKLVPSLADSWTVSKD
GLTYDFKLHPGVKFHTTDYFKPTRELSADDVLFSFQRMLDPQNPWHKIAQSGFPHAQSMQLPALIKSIEAPDAHTVRFTL
NHADSTFLATLSMGFASIYSAEYTAQLLKAGTPEKLNSQPIGTGPFVFKRFQKDAVVRYEAFDDYFAGKSDIDTLVYAIT
PDANVRLQKIRQDECQIALSPKPLDIQAASKDDSLKVEKTEAFMTAFVAINSQHPPFDKPEVRQAINLAFDRDNYLKAVF
EGTAEKANGPYPPNTWSYAKDLPGYQHDVAKAKALLAKAGVKEGFKTTIWTRPSGSLLNPNPSLGAQLLQADLKQIGINA
EIKIIEWGELIRRAKAGEHDLLFMGWAGDNGDPDNFLTPQFSCAAVQSGTNFARYCDKTLDKLIADGKSVSDQGERSKLY
HQAQQQIQQQALWIPLAHPTAAALVRKDVTGYQVSPFGRQDFYKVQVK
>Mature_528_residues
MRLAALPFLLVPLLLPVAAQASNLVVCTEASPEGFDVVQYNSLTTTNASADVLMNRLVDFDAKSGKLVPSLADSWTVSKD
GLTYDFKLHPGVKFHTTDYFKPTRELSADDVLFSFQRMLDPQNPWHKIAQSGFPHAQSMQLPALIKSIEAPDAHTVRFTL
NHADSTFLATLSMGFASIYSAEYTAQLLKAGTPEKLNSQPIGTGPFVFKRFQKDAVVRYEAFDDYFAGKSDIDTLVYAIT
PDANVRLQKIRQDECQIALSPKPLDIQAASKDDSLKVEKTEAFMTAFVAINSQHPPFDKPEVRQAINLAFDRDNYLKAVF
EGTAEKANGPYPPNTWSYAKDLPGYQHDVAKAKALLAKAGVKEGFKTTIWTRPSGSLLNPNPSLGAQLLQADLKQIGINA
EIKIIEWGELIRRAKAGEHDLLFMGWAGDNGDPDNFLTPQFSCAAVQSGTNFARYCDKTLDKLIADGKSVSDQGERSKLY
HQAQQQIQQQALWIPLAHPTAAALVRKDVTGYQVSPFGRQDFYKVQVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=526, Percent_Identity=43.7262357414449, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI1787551, Length=504, Percent_Identity=33.531746031746, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1787052, Length=515, Percent_Identity=28.7378640776699, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1787762, Length=526, Percent_Identity=25.6653992395437, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787495, Length=508, Percent_Identity=25, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789887, Length=496, Percent_Identity=25.6048387096774, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87081878, Length=522, Percent_Identity=23.9463601532567, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789397, Length=473, Percent_Identity=21.5644820295983, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58353; Mature: 58353

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAALPFLLVPLLLPVAAQASNLVVCTEASPEGFDVVQYNSLTTTNASADVLMNRLVDF
CCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCEECCCCHHHHHHHHHHCC
DAKSGKLVPSLADSWTVSKDGLTYDFKLHPGVKFHTTDYFKPTRELSADDVLFSFQRMLD
CCCCCCCCCCCCCCCEECCCCEEEEEEECCCEEEEECCCCCCHHHCCHHHHHHHHHHHCC
PQNPWHKIAQSGFPHAQSMQLPALIKSIEAPDAHTVRFTLNHADSTFLATLSMGFASIYS
CCCHHHHHHHCCCCCHHCCCHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
AEYTAQLLKAGTPEKLNSQPIGTGPFVFKRFQKDAVVRYEAFDDYFAGKSDIDTLVYAIT
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECHHHHCCCCCCCCEEEEEEC
PDANVRLQKIRQDECQIALSPKPLDIQAASKDDSLKVEKTEAFMTAFVAINSQHPPFDKP
CCCCCHHHHHCCCCCEEEECCCCCEEEECCCCCCEEEEHHHHHHEEEEEECCCCCCCCCH
EVRQAINLAFDRDNYLKAVFEGTAEKANGPYPPNTWSYAKDLPGYQHDVAKAKALLAKAG
HHHHHHHHHCCCCHHHHHHHHCCHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
VKEGFKTTIWTRPSGSLLNPNPSLGAQLLQADLKQIGINAEIKIIEWGELIRRAKAGEHD
HCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCC
LLFMGWAGDNGDPDNFLTPQFSCAAVQSGTNFARYCDKTLDKLIADGKSVSDQGERSKLY
EEEEEECCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
HQAQQQIQQQALWIPLAHPTAAALVRKDVTGYQVSPFGRQDFYKVQVK
HHHHHHHHHHHEEEEECCCHHHHHHHHCCCCCEECCCCCCCEEEEEEC
>Mature Secondary Structure
MRLAALPFLLVPLLLPVAAQASNLVVCTEASPEGFDVVQYNSLTTTNASADVLMNRLVDF
CCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCEECCCCHHHHHHHHHHCC
DAKSGKLVPSLADSWTVSKDGLTYDFKLHPGVKFHTTDYFKPTRELSADDVLFSFQRMLD
CCCCCCCCCCCCCCCEECCCCEEEEEEECCCEEEEECCCCCCHHHCCHHHHHHHHHHHCC
PQNPWHKIAQSGFPHAQSMQLPALIKSIEAPDAHTVRFTLNHADSTFLATLSMGFASIYS
CCCHHHHHHHCCCCCHHCCCHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
AEYTAQLLKAGTPEKLNSQPIGTGPFVFKRFQKDAVVRYEAFDDYFAGKSDIDTLVYAIT
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECHHHHCCCCCCCCEEEEEEC
PDANVRLQKIRQDECQIALSPKPLDIQAASKDDSLKVEKTEAFMTAFVAINSQHPPFDKP
CCCCCHHHHHCCCCCEEEECCCCCEEEECCCCCCEEEEHHHHHHEEEEEECCCCCCCCCH
EVRQAINLAFDRDNYLKAVFEGTAEKANGPYPPNTWSYAKDLPGYQHDVAKAKALLAKAG
HHHHHHHHHCCCCHHHHHHHHCCHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
VKEGFKTTIWTRPSGSLLNPNPSLGAQLLQADLKQIGINAEIKIIEWGELIRRAKAGEHD
HCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCC
LLFMGWAGDNGDPDNFLTPQFSCAAVQSGTNFARYCDKTLDKLIADGKSVSDQGERSKLY
EEEEEECCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
HQAQQQIQQQALWIPLAHPTAAALVRKDVTGYQVSPFGRQDFYKVQVK
HHHHHHHHHHHEEEEECCCHHHHHHHHCCCCCEECCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]