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The map label for this gene is hemX [H]

Identifier: 66043331

GI number: 66043331

Start: 59526

End: 60701

Strand: Reverse

Name: hemX [H]

Synonym: Psyr_0060

Alternate gene names: 66043331

Gene position: 60701-59526 (Counterclockwise)

Preceding gene: 66043332

Following gene: 66043330

Centisome position: 1.0

GC content: 63.18

Gene sequence:

>1176_bases
ATGATCGACACCTGTCGTTTACGCTATTACGCCAAAATGCAAAGGATGGGATACGTGAGCGAAACAGCCTTGCCTAAAGA
CGAAGAATCGGTGTTGAAAACGCCTGCATCCAAGCCTGAGCCAGTCCGCACCGAGCGCACCGGCAGCCGCAACAGTGGCC
TGGTATTCCTGGCCTTGCTGCTGGCAATTGCCGGTATCGCCGTCGCCGGCTGGGGAGTCTGGCAACTGCGCATGTTGCAG
GCCGGGCACCAGCAACAGCGCGGACAGGTCGAGGACATCGCCGAACAGACCCTGGTGCTGGCGCAGAATGACCAGCAACT
GAGCGCACGTATCGCGCAATTCCCGCCAGCCAACCAACTGGAAGACAGCCGCCGTCTGGTCGCGCAACTGCAAGGCGATC
AGCAGCGTCTCAGCCAGCGACTCGAAACCGTGCTGGGGGCGAGCCGCAAGGACTGGCGTCTGGCCGAGGCCGAACATCTG
CTGCGTCTGGCCAGCCTGCGCCTTTCAGCGCTGCAGGACATCAACAGCGCGCAGGCGCTGGTTCAGGGTGCCGACGAAAT
TCTGCGTGAGCAGGATGATCCAGGCTCCTTCGCTGCCCGCGAGCAACTGGCCAAGAGCCTTGCCGCCCTGCGCAGCGTCG
AGCAGCCGGACCGCACCGGGCTGTTTCTGCAACTGGCTGCCTTGCGTGAGCAGGCTGTACAGCTCAACAAGCTGGCTCCC
GAATACGCAGACAAGGGCGAGTCGCTTATGGGGCTGACCGCTGACAAGACCGAAACCAGCCGGTGGTCGCAGTGGTGGGA
CGAGATCTCCCATTACTTCCGTATCGATTTCAACGCCGACAAGGACATCCGCCCGGTACTCGCCGGCCAGAGCCTTTCGC
AGGTGCGTCTGGCCCTGAGCCTGGCGCTGGAGCAGGCGCAGTGGGCAGCGCTTAACGGCGAGCCCGAGGTTTATTCCAAG
GCCATCACCGAAGCGCAGAGCGTTCTGAAAGCCAACTTCGATCAGGACGACCCACAGGGCAAGGCGCTCGGCCAAGGGCT
TGATGCCGTCGCCAGCCAGCCGGTATCGGTGAAGACACCGGATCTGGCACCAACCCTGAGCGCCGTGCAGGCCTACCTTG
AACGCCGTCACGCTGCCGGCCAGCCAGCCGAGGCGCAACAGGGGACCAGCCGATGA

Upstream 100 bases:

>100_bases
GGGCAGCCGGAGCAAGGACCGTTATTGATTGTCGTGGCGCCAGCGCCACGGCATTGCTGGCAGCGTTGCGGGAACAACCT
CAGCCTGCCGTCAAGGCGTA

Downstream 100 bases:

>100_bases
AGCGCTTCTATGTGCTGTTATTCATCGCGATCGCCGCTGCGGCGCTGATCGGGGTCGCCATCGCCGAGCATTCCGGCTAT
GTCCTGATCGCCTATCAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MIDTCRLRYYAKMQRMGYVSETALPKDEESVLKTPASKPEPVRTERTGSRNSGLVFLALLLAIAGIAVAGWGVWQLRMLQ
AGHQQQRGQVEDIAEQTLVLAQNDQQLSARIAQFPPANQLEDSRRLVAQLQGDQQRLSQRLETVLGASRKDWRLAEAEHL
LRLASLRLSALQDINSAQALVQGADEILREQDDPGSFAAREQLAKSLAALRSVEQPDRTGLFLQLAALREQAVQLNKLAP
EYADKGESLMGLTADKTETSRWSQWWDEISHYFRIDFNADKDIRPVLAGQSLSQVRLALSLALEQAQWAALNGEPEVYSK
AITEAQSVLKANFDQDDPQGKALGQGLDAVASQPVSVKTPDLAPTLSAVQAYLERRHAAGQPAEAQQGTSR

Sequences:

>Translated_391_residues
MIDTCRLRYYAKMQRMGYVSETALPKDEESVLKTPASKPEPVRTERTGSRNSGLVFLALLLAIAGIAVAGWGVWQLRMLQ
AGHQQQRGQVEDIAEQTLVLAQNDQQLSARIAQFPPANQLEDSRRLVAQLQGDQQRLSQRLETVLGASRKDWRLAEAEHL
LRLASLRLSALQDINSAQALVQGADEILREQDDPGSFAAREQLAKSLAALRSVEQPDRTGLFLQLAALREQAVQLNKLAP
EYADKGESLMGLTADKTETSRWSQWWDEISHYFRIDFNADKDIRPVLAGQSLSQVRLALSLALEQAQWAALNGEPEVYSK
AITEAQSVLKANFDQDDPQGKALGQGLDAVASQPVSVKTPDLAPTLSAVQAYLERRHAAGQPAEAQQGTSR
>Mature_391_residues
MIDTCRLRYYAKMQRMGYVSETALPKDEESVLKTPASKPEPVRTERTGSRNSGLVFLALLLAIAGIAVAGWGVWQLRMLQ
AGHQQQRGQVEDIAEQTLVLAQNDQQLSARIAQFPPANQLEDSRRLVAQLQGDQQRLSQRLETVLGASRKDWRLAEAEHL
LRLASLRLSALQDINSAQALVQGADEILREQDDPGSFAAREQLAKSLAALRSVEQPDRTGLFLQLAALREQAVQLNKLAP
EYADKGESLMGLTADKTETSRWSQWWDEISHYFRIDFNADKDIRPVLAGQSLSQVRLALSLALEQAQWAALNGEPEVYSK
AITEAQSVLKANFDQDDPQGKALGQGLDAVASQPVSVKTPDLAPTLSAVQAYLERRHAAGQPAEAQQGTSR

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=378, Percent_Identity=28.042328042328, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 43109; Mature: 43109

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTCRLRYYAKMQRMGYVSETALPKDEESVLKTPASKPEPVRTERTGSRNSGLVFLALL
CCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAIAGIAVAGWGVWQLRMLQAGHQQQRGQVEDIAEQTLVLAQNDQQLSARIAQFPPANQL
HHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCH
EDSRRLVAQLQGDQQRLSQRLETVLGASRKDWRLAEAEHLLRLASLRLSALQDINSAQAL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGADEILREQDDPGSFAAREQLAKSLAALRSVEQPDRTGLFLQLAALREQAVQLNKLAP
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
EYADKGESLMGLTADKTETSRWSQWWDEISHYFRIDFNADKDIRPVLAGQSLSQVRLALS
HHHCCCCCEECCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCCHHHHHHHHHH
LALEQAQWAALNGEPEVYSKAITEAQSVLKANFDQDDPQGKALGQGLDAVASQPVSVKTP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHCCCCCCCCC
DLAPTLSAVQAYLERRHAAGQPAEAQQGTSR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIDTCRLRYYAKMQRMGYVSETALPKDEESVLKTPASKPEPVRTERTGSRNSGLVFLALL
CCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAIAGIAVAGWGVWQLRMLQAGHQQQRGQVEDIAEQTLVLAQNDQQLSARIAQFPPANQL
HHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCH
EDSRRLVAQLQGDQQRLSQRLETVLGASRKDWRLAEAEHLLRLASLRLSALQDINSAQAL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGADEILREQDDPGSFAAREQLAKSLAALRSVEQPDRTGLFLQLAALREQAVQLNKLAP
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
EYADKGESLMGLTADKTETSRWSQWWDEISHYFRIDFNADKDIRPVLAGQSLSQVRLALS
HHHCCCCCEECCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCCHHHHHHHHHH
LALEQAQWAALNGEPEVYSKAITEAQSVLKANFDQDDPQGKALGQGLDAVASQPVSVKTP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHCCCCCCCCC
DLAPTLSAVQAYLERRHAAGQPAEAQQGTSR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]