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The map label for this gene is yaeL [C]

Identifier: 62390854

GI number: 62390854

Start: 2098716

End: 2099930

Strand: Reverse

Name: yaeL [C]

Synonym: cg2207

Alternate gene names: 62390854

Gene position: 2099930-2098716 (Counterclockwise)

Preceding gene: 62390855

Following gene: 62390853

Centisome position: 63.97

GC content: 57.45

Gene sequence:

>1215_bases
GTGGCAGCCTATCTTCTTGGTGTCGTATTATTTTTCCTCGGCATCGCAGTAACCATCGCGCTTCACGAGTGGGGGCACTT
CATCACAGCGCGCATTTTCGGAATGAAAGTGCGGCGTTTCTTCATCGGTTTCGGCCCGACGGTGTTTGCCAAAAGACGCG
GCGAAACCGTGTACGGCCTTAAAGCGATTCCGGTCGGCGGTTTTTGTGACATCGCGGGGATGACTGCCCAAGATGAACTT
GATCCGGAAGACCTGCCGCGCGCCATGTATCTAAAGCCCTGGTGGCAGCGCATAATTGTGCTTTCCGGCGGCGTGATCAT
GAATCTGATCGTCGGCTTTTTGGTGCTTTACGGCGTGGCGGTGAGCTCCGGAATCCCGAATCCGGATGTGGATACCACCG
CGACAGTCGACACCGTTCAGTGCGTGCCGGAAACCCAAATTTCCGCAACTGAACTGTCCTCCTGCGTAGGTTCAGGCCCA
GCGGGCGACGCCGGCATTGAGCACGGCGATAAGATTTTGGCCGTCAACGGCCAAGAGATGGCAAGCTTCACCGCCATCCG
CGATGCGATCCTCGAGCTCCCAGGCGAAACGGCAACGCTGACGATTGAACGGGAGGGAACGCTTTTCGACGTCGACCTCC
AGGTTGCCTCTGTCACCCGTCTCGCCTCTGACGGTTCAGAAATTACCGTCGGCGCGGTGGGCATGTCGAGCCTTCCACCG
ACCGATGTGTACAAAAAATACGGCCCAATCGAGGGTGTGGGAGCAACTGCACGTTTCACCGGCGACATGATCAGCGCCAC
GTGGGATGGCCTCAAAGCCTTCCCGGCGAAAATCCCAGGGGTCGTCGCATCCATCTTCGGTGCAGAACGAGATGTAGAAA
GCCCCATGAGTGTGGTGGGCGCGTCACGCATCGGCGGCGAATTTGTCGAACGTTCCATGTGGGACATGTTCATGATGATG
CTGGCCAGCCTGAACTTCTTCCTCGCGCTGTTTAACCTCGTGCCGCTGCCACCACTTGATGGCGGACACATTGCCGTGGT
GATCTATGAAAAAATCCGCGACTTCTTCCGCAAACTGCGCGGAAAACCAGCGGGCGGCCCAGCGGATTACACCAAACTAA
TGCCCGTCACCGTAGCTGTCGCAGCCTTGCTGATGACAGTGGGAGGCCTGGTCATTGTCGCCGATGTGGTCAATCCCATC
CGACTCTTTGGCTAA

Upstream 100 bases:

>100_bases
GTCGATGATATTTTGGCAACCGAATCTGAGGCACGCGCGCGTGCGAATGCTTTGATCAACCGGTTGGCAACCAACTTGTA
AGCTAAGGAGCTTCCGCCTC

Downstream 100 bases:

>100_bases
CGATACGGAATTGAACTGCCGGCACCGATGTTAAAAGAGGTGACGGTGATACAATTTTGCCATAACTGACTTAACCCAGA
ACGTTGTCCGGAAGCACACA

Product: membrane-embedded Zn-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MAAYLLGVVLFFLGIAVTIALHEWGHFITARIFGMKVRRFFIGFGPTVFAKRRGETVYGLKAIPVGGFCDIAGMTAQDEL
DPEDLPRAMYLKPWWQRIIVLSGGVIMNLIVGFLVLYGVAVSSGIPNPDVDTTATVDTVQCVPETQISATELSSCVGSGP
AGDAGIEHGDKILAVNGQEMASFTAIRDAILELPGETATLTIEREGTLFDVDLQVASVTRLASDGSEITVGAVGMSSLPP
TDVYKKYGPIEGVGATARFTGDMISATWDGLKAFPAKIPGVVASIFGAERDVESPMSVVGASRIGGEFVERSMWDMFMMM
LASLNFFLALFNLVPLPPLDGGHIAVVIYEKIRDFFRKLRGKPAGGPADYTKLMPVTVAVAALLMTVGGLVIVADVVNPI
RLFG

Sequences:

>Translated_404_residues
MAAYLLGVVLFFLGIAVTIALHEWGHFITARIFGMKVRRFFIGFGPTVFAKRRGETVYGLKAIPVGGFCDIAGMTAQDEL
DPEDLPRAMYLKPWWQRIIVLSGGVIMNLIVGFLVLYGVAVSSGIPNPDVDTTATVDTVQCVPETQISATELSSCVGSGP
AGDAGIEHGDKILAVNGQEMASFTAIRDAILELPGETATLTIEREGTLFDVDLQVASVTRLASDGSEITVGAVGMSSLPP
TDVYKKYGPIEGVGATARFTGDMISATWDGLKAFPAKIPGVVASIFGAERDVESPMSVVGASRIGGEFVERSMWDMFMMM
LASLNFFLALFNLVPLPPLDGGHIAVVIYEKIRDFFRKLRGKPAGGPADYTKLMPVTVAVAALLMTVGGLVIVADVVNPI
RLFG
>Mature_403_residues
AAYLLGVVLFFLGIAVTIALHEWGHFITARIFGMKVRRFFIGFGPTVFAKRRGETVYGLKAIPVGGFCDIAGMTAQDELD
PEDLPRAMYLKPWWQRIIVLSGGVIMNLIVGFLVLYGVAVSSGIPNPDVDTTATVDTVQCVPETQISATELSSCVGSGPA
GDAGIEHGDKILAVNGQEMASFTAIRDAILELPGETATLTIEREGTLFDVDLQVASVTRLASDGSEITVGAVGMSSLPPT
DVYKKYGPIEGVGATARFTGDMISATWDGLKAFPAKIPGVVASIFGAERDVESPMSVVGASRIGGEFVERSMWDMFMMML
ASLNFFLALFNLVPLPPLDGGHIAVVIYEKIRDFFRKLRGKPAGGPADYTKLMPVTVAVAALLMTVGGLVIVADVVNPIR
LFG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=206, Percent_Identity=27.1844660194175, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 43045; Mature: 42914

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAYLLGVVLFFLGIAVTIALHEWGHFITARIFGMKVRRFFIGFGPTVFAKRRGETVYGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEE
KAIPVGGFCDIAGMTAQDELDPEDLPRAMYLKPWWQRIIVLSGGVIMNLIVGFLVLYGVA
EECCCCCCCCCCCCCCCCCCCHHHCCCHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSSGIPNPDVDTTATVDTVQCVPETQISATELSSCVGSGPAGDAGIEHGDKILAVNGQEM
HHCCCCCCCCCCCCCCHHEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHH
ASFTAIRDAILELPGETATLTIEREGTLFDVDLQVASVTRLASDGSEITVGAVGMSSLPP
HHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCCCCCC
TDVYKKYGPIEGVGATARFTGDMISATWDGLKAFPAKIPGVVASIFGAERDVESPMSVVG
HHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ASRIGGEFVERSMWDMFMMMLASLNFFLALFNLVPLPPLDGGHIAVVIYEKIRDFFRKLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHC
GKPAGGPADYTKLMPVTVAVAALLMTVGGLVIVADVVNPIRLFG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAYLLGVVLFFLGIAVTIALHEWGHFITARIFGMKVRRFFIGFGPTVFAKRRGETVYGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEE
KAIPVGGFCDIAGMTAQDELDPEDLPRAMYLKPWWQRIIVLSGGVIMNLIVGFLVLYGVA
EECCCCCCCCCCCCCCCCCCCHHHCCCHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSSGIPNPDVDTTATVDTVQCVPETQISATELSSCVGSGPAGDAGIEHGDKILAVNGQEM
HHCCCCCCCCCCCCCCHHEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHH
ASFTAIRDAILELPGETATLTIEREGTLFDVDLQVASVTRLASDGSEITVGAVGMSSLPP
HHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCCCCCC
TDVYKKYGPIEGVGATARFTGDMISATWDGLKAFPAKIPGVVASIFGAERDVESPMSVVG
HHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ASRIGGEFVERSMWDMFMMMLASLNFFLALFNLVPLPPLDGGHIAVVIYEKIRDFFRKLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHC
GKPAGGPADYTKLMPVTVAVAALLMTVGGLVIVADVVNPIRLFG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]