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The map label for this gene is efp1 [H]

Identifier: 62185163

GI number: 62185163

Start: 617472

End: 618029

Strand: Direct

Name: efp1 [H]

Synonym: CAB538

Alternate gene names: 62185163

Gene position: 617472-618029 (Clockwise)

Preceding gene: 62185162

Following gene: 161501894

Centisome position: 53.96

GC content: 34.95

Gene sequence:

>558_bases
ATGGTATTAAGTAGCCAGCTCTCTGTGGGAATGTTTATTTCCACAAAAGATGGTCTTTATAAAGTCGTGGCGGTTTCTAA
AGTCACAGGCAATAAAGGGGAATCTTTTATCAAAGCTTCGTTAAAATCTGCCGATTCCGAAGTCATTATTGAAAGAAATT
TTAAAATTGGCCAAGAAATAAAAGAAGCCCAGTTTGAATCCAGAAATCTTGAATATCTGTATATTGAGGATGACCACTTT
CTTTTCCTTGATTTGGGAAATTATGAAAAAATCCATATCCCTAAAGAAATCATGAAGGATAATTTTTTATTCTTAAAAGC
AGGAGTCACCGTTTCTGCCTTGGTTTATGATAATGTTGTTTTTTCTATAGAGTTGCCTCACTTCTTAGAGTTGATGGTGT
CTAAAACAGATTTCCCCGGGGATTCACTTTTAATTGCCGGTGGTACAAAAAAAGCTTTATTAGAAACAGGCATCGAAATT
ACAGTACCTCCTTTCATAGAAATTGGGGATATTATAAAAATTGATACGCGCACGTGTGAATATATTCAACGCGTCTAA

Upstream 100 bases:

>100_bases
CGTGAAGCAGGTGCGGATATTCTCGTGGCTGCATCATACATATTCGAAAAGAACGAACAGACTATGGAAGAAAAAGTTTT
GCTACTTCGAGGAGAAAATC

Downstream 100 bases:

>100_bases
CTTCAGGCTGAGAAGATAAGAGAAAATAAATATGGATTTAAAGCAAATAGAAAAGCTCATGATTGCTATGGGACGTAATA
GCATGAAGCGTTTTGTGATA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 1 [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MVLSSQLSVGMFISTKDGLYKVVAVSKVTGNKGESFIKASLKSADSEVIIERNFKIGQEIKEAQFESRNLEYLYIEDDHF
LFLDLGNYEKIHIPKEIMKDNFLFLKAGVTVSALVYDNVVFSIELPHFLELMVSKTDFPGDSLLIAGGTKKALLETGIEI
TVPPFIEIGDIIKIDTRTCEYIQRV

Sequences:

>Translated_185_residues
MVLSSQLSVGMFISTKDGLYKVVAVSKVTGNKGESFIKASLKSADSEVIIERNFKIGQEIKEAQFESRNLEYLYIEDDHF
LFLDLGNYEKIHIPKEIMKDNFLFLKAGVTVSALVYDNVVFSIELPHFLELMVSKTDFPGDSLLIAGGTKKALLETGIEI
TVPPFIEIGDIIKIDTRTCEYIQRV
>Mature_185_residues
MVLSSQLSVGMFISTKDGLYKVVAVSKVTGNKGESFIKASLKSADSEVIIERNFKIGQEIKEAQFESRNLEYLYIEDDHF
LFLDLGNYEKIHIPKEIMKDNFLFLKAGVTVSALVYDNVVFSIELPHFLELMVSKTDFPGDSLLIAGGTKKALLETGIEI
TVPPFIEIGDIIKIDTRTCEYIQRV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=30.6010928961749, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20775; Mature: 20775

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSSQLSVGMFISTKDGLYKVVAVSKVTGNKGESFIKASLKSADSEVIIERNFKIGQEI
CEECCCCCEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHH
KEAQFESRNLEYLYIEDDHFLFLDLGNYEKIHIPKEIMKDNFLFLKAGVTVSALVYDNVV
HHHHHHCCCEEEEEEECCCEEEEECCCCEEEECCHHHHCCCEEEEEECCEEEEEEECCEE
FSIELPHFLELMVSKTDFPGDSLLIAGGTKKALLETGIEITVPPFIEIGDIIKIDTRTCE
EEEECHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCEEEECCCEECCCEEEECCHHHH
YIQRV
HHHCC
>Mature Secondary Structure
MVLSSQLSVGMFISTKDGLYKVVAVSKVTGNKGESFIKASLKSADSEVIIERNFKIGQEI
CEECCCCCEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHH
KEAQFESRNLEYLYIEDDHFLFLDLGNYEKIHIPKEIMKDNFLFLKAGVTVSALVYDNVV
HHHHHHCCCEEEEEEECCCEEEEECCCCEEEECCHHHHCCCEEEEEECCEEEEEEECCEE
FSIELPHFLELMVSKTDFPGDSLLIAGGTKKALLETGIEITVPPFIEIGDIIKIDTRTCE
EEEECHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCEEEECCCEECCCEEEECCHHHH
YIQRV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]