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The map label for this gene is clpP1 [H]

Identifier: 62184864

GI number: 62184864

Start: 242439

End: 243017

Strand: Direct

Name: clpP1 [H]

Synonym: CAB222

Alternate gene names: 62184864

Gene position: 242439-243017 (Clockwise)

Preceding gene: 62184863

Following gene: 62184865

Centisome position: 21.19

GC content: 42.31

Gene sequence:

>579_bases
ATGGCTGATGGGGAAGTAGAGAATAAGTTACGAGATGTTATAGAGAGAAAAATCTTAGATGCCCGTCGGGTATTTTTTTC
TGAGCCTGTAACGGATAAGAGCGCAGCAGATGCTATTAAGAAGTTATGGTATTTAGAACTTACCAATCCTGGTCAACCTA
TAGTATTCGTAATTAATAGCCCTGGAGGTTCGGTAGACGCAGGATTTGCAGTGTGGGATCAGATAAAAATGATGACATCC
CCAGTGACTACTGTAGTTACAGGATTAGCTGCTTCTATGGGATCGGTATTAAGTTTATGTGCAGCTCCAGGACGTCGTTT
CGCCACTCCTCATTCGCGTATCATGATTCACCAGCCATCTATAGGCGGGCCAATCACTGGACAAGCTACCGATTTAGATA
TTCATGCTCGTGAAATCTTAAAAACAAAGAAACGTATAGTTGATGTGTATTTAGAGGCGACCGGGCAGTCTCGAGAAGTG
ATTGAAAAGGCCATCGATCGAGACACTTGGATGACAGCAGACGAAGCCAAAGATTTTGGTTTATTAGATGGCATCCTCTT
CTCATTCAATGATTTATAA

Upstream 100 bases:

>100_bases
GAAGAAGCAAGAGCTCGAGTCGCAGGCTTATTATCGCGGTTCCCGCTTTATCCTGAAATCGATCTGGAAACTTTAGTTTA
GTTAGGAGATATGTTGTTCT

Downstream 100 bases:

>100_bases
GCCTAGCTTATATTCTGGGGCAGGGAATCGCTTTATCCTAAGTGAAACTTGTCCCGATATGACAATACTTCCTAGTCTAT
GTAAGGAATATCAAGTAGAT

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MADGEVENKLRDVIERKILDARRVFFSEPVTDKSAADAIKKLWYLELTNPGQPIVFVINSPGGSVDAGFAVWDQIKMMTS
PVTTVVTGLAASMGSVLSLCAAPGRRFATPHSRIMIHQPSIGGPITGQATDLDIHAREILKTKKRIVDVYLEATGQSREV
IEKAIDRDTWMTADEAKDFGLLDGILFSFNDL

Sequences:

>Translated_192_residues
MADGEVENKLRDVIERKILDARRVFFSEPVTDKSAADAIKKLWYLELTNPGQPIVFVINSPGGSVDAGFAVWDQIKMMTS
PVTTVVTGLAASMGSVLSLCAAPGRRFATPHSRIMIHQPSIGGPITGQATDLDIHAREILKTKKRIVDVYLEATGQSREV
IEKAIDRDTWMTADEAKDFGLLDGILFSFNDL
>Mature_191_residues
ADGEVENKLRDVIERKILDARRVFFSEPVTDKSAADAIKKLWYLELTNPGQPIVFVINSPGGSVDAGFAVWDQIKMMTSP
VTTVVTGLAASMGSVLSLCAAPGRRFATPHSRIMIHQPSIGGPITGQATDLDIHAREILKTKKRIVDVYLEATGQSREVI
EKAIDRDTWMTADEAKDFGLLDGILFSFNDL

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=173, Percent_Identity=44.5086705202312, Blast_Score=150, Evalue=8e-37,
Organism=Escherichia coli, GI1786641, Length=177, Percent_Identity=43.5028248587571, Blast_Score=150, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17538017, Length=172, Percent_Identity=45.3488372093023, Blast_Score=145, Evalue=9e-36,
Organism=Drosophila melanogaster, GI20129427, Length=170, Percent_Identity=39.4117647058824, Blast_Score=139, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 21046; Mature: 20915

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGEVENKLRDVIERKILDARRVFFSEPVTDKSAADAIKKLWYLELTNPGQPIVFVINS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCCCCCEEEEEEC
PGGSVDAGFAVWDQIKMMTSPVTTVVTGLAASMGSVLSLCAAPGRRFATPHSRIMIHQPS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
IGGPITGQATDLDIHAREILKTKKRIVDVYLEATGQSREVIEKAIDRDTWMTADEAKDFG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHCCCCH
LLDGILFSFNDL
HHHHHHHHHCCC
>Mature Secondary Structure 
ADGEVENKLRDVIERKILDARRVFFSEPVTDKSAADAIKKLWYLELTNPGQPIVFVINS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCCCCCEEEEEEC
PGGSVDAGFAVWDQIKMMTSPVTTVVTGLAASMGSVLSLCAAPGRRFATPHSRIMIHQPS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
IGGPITGQATDLDIHAREILKTKKRIVDVYLEATGQSREVIEKAIDRDTWMTADEAKDFG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHCCCCH
LLDGILFSFNDL
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA