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The map label for this gene is agaC [H]

Identifier: 59714185

GI number: 59714185

Start: 1126059

End: 1126829

Strand: Reverse

Name: agaC [H]

Synonym: VF_A1002

Alternate gene names: 59714185

Gene position: 1126829-1126059 (Counterclockwise)

Preceding gene: 59714186

Following gene: 59714184

Centisome position: 84.7

GC content: 42.02

Gene sequence:

>771_bases
ATGTTATTTGAAGCAAGTTTAGTGGCAGTGTGGGCATTCTTCTGTGGTATCGATAAATACGATGTCGCATTGAATATCCA
TAGACCACTTATCACAGGACCTGTTGTTGGTCTAATTATGGGCGATATGCAAATTGGCTTAATCGCTGGTGCAACGCTGG
AACTCGCATGGTTAGGTCTAGTGCCTAACGCTGGGGCACAGCCGCCAGATGTAACTATGGGTACGATTGCTGCTGTAGCA
TTCGCTGTAATGACAGGACAATCACCAGAAGTTGCTATGGGTGTTGGTATGCCTATCGCAGTATTAATGCAAATGCTTGT
TATCGGTTTCTTTGCTATGACCTCATTTACCATGGGTAAAGCAGATAAATACGCTGAAGAAGCGAATACAAATGGCATTG
ATTTTCTCTTACTTTCCACGATTACAATGCGTTCAATGCTCTACGCTGTGATTGCCTTCTTGACCGTTTATTTTGGTGAA
CATGGCGCAGCTTGGATTGATGCTAATGCTCCGAAAACTCTATTAGAAGGATTAGGTATCGGGGCGAAAATGGTTCCTGC
AATTGGTTTTGCAATGCTATTGAAAATTATGTGGTCAAAAGAAGTGGCGGGTGTGTTCTTTATCGGTTTTGTAATGACAA
CGTATTTACAGCTTCCGATCATGGCCGTGGCAATTTTAGGGGCATCAGCAGCCGCTCTATATTACTTCTTTAGTGGAAAT
GGAAACAAAAATTCAAATCAAGAATTTGAGGACTTTGAAGATGGTATCTAA

Upstream 100 bases:

>100_bases
ATGGTGGAAAAGGGCGTGACATGCACGGTTCAAAATACACCAGATCAAACACCAATTAACGTTCTTGAACTAGCAAAAAC
AGCAGCCTAGGTAGGTACTT

Downstream 100 bases:

>100_bases
AACAGAAAATCCGAACGCTCTAATTGATGGCATTGATGAGTTTCAAGGTACTCAAGTGGCGAATCCTAAGAGCTTGGTTG
ATGGTATCGACGAATATCAA

Product: PTS system, N-acetylgalactosamine-specific IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Aga; PTS system N-acetylgalactosamine-specific EIIC component 1 [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLFEASLVAVWAFFCGIDKYDVALNIHRPLITGPVVGLIMGDMQIGLIAGATLELAWLGLVPNAGAQPPDVTMGTIAAVA
FAVMTGQSPEVAMGVGMPIAVLMQMLVIGFFAMTSFTMGKADKYAEEANTNGIDFLLLSTITMRSMLYAVIAFLTVYFGE
HGAAWIDANAPKTLLEGLGIGAKMVPAIGFAMLLKIMWSKEVAGVFFIGFVMTTYLQLPIMAVAILGASAAALYYFFSGN
GNKNSNQEFEDFEDGI

Sequences:

>Translated_256_residues
MLFEASLVAVWAFFCGIDKYDVALNIHRPLITGPVVGLIMGDMQIGLIAGATLELAWLGLVPNAGAQPPDVTMGTIAAVA
FAVMTGQSPEVAMGVGMPIAVLMQMLVIGFFAMTSFTMGKADKYAEEANTNGIDFLLLSTITMRSMLYAVIAFLTVYFGE
HGAAWIDANAPKTLLEGLGIGAKMVPAIGFAMLLKIMWSKEVAGVFFIGFVMTTYLQLPIMAVAILGASAAALYYFFSGN
GNKNSNQEFEDFEDGI
>Mature_256_residues
MLFEASLVAVWAFFCGIDKYDVALNIHRPLITGPVVGLIMGDMQIGLIAGATLELAWLGLVPNAGAQPPDVTMGTIAAVA
FAVMTGQSPEVAMGVGMPIAVLMQMLVIGFFAMTSFTMGKADKYAEEANTNGIDFLLLSTITMRSMLYAVIAFLTVYFGE
HGAAWIDANAPKTLLEGLGIGAKMVPAIGFAMLLKIMWSKEVAGVFFIGFVMTTYLQLPIMAVAILGASAAALYYFFSGN
GNKNSNQEFEDFEDGI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1789528, Length=263, Percent_Identity=34.6007604562738, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788121, Length=244, Percent_Identity=28.2786885245902, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: 2.7.1.69

Molecular weight: Translated: 27270; Mature: 27270

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFEASLVAVWAFFCGIDKYDVALNIHRPLITGPVVGLIMGDMQIGLIAGATLELAWLGL
CCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCHHEEHEECCHHHEEEEEE
VPNAGAQPPDVTMGTIAAVAFAVMTGQSPEVAMGVGMPIAVLMQMLVIGFFAMTSFTMGK
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
ADKYAEEANTNGIDFLLLSTITMRSMLYAVIAFLTVYFGEHGAAWIDANAPKTLLEGLGI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCC
GAKMVPAIGFAMLLKIMWSKEVAGVFFIGFVMTTYLQLPIMAVAILGASAAALYYFFSGN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCC
GNKNSNQEFEDFEDGI
CCCCCCCCHHHHHCCC
>Mature Secondary Structure
MLFEASLVAVWAFFCGIDKYDVALNIHRPLITGPVVGLIMGDMQIGLIAGATLELAWLGL
CCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCHHEEHEECCHHHEEEEEE
VPNAGAQPPDVTMGTIAAVAFAVMTGQSPEVAMGVGMPIAVLMQMLVIGFFAMTSFTMGK
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
ADKYAEEANTNGIDFLLLSTITMRSMLYAVIAFLTVYFGEHGAAWIDANAPKTLLEGLGI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCC
GAKMVPAIGFAMLLKIMWSKEVAGVFFIGFVMTTYLQLPIMAVAILGASAAALYYFFSGN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCC
GNKNSNQEFEDFEDGI
CCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]