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The map label for this gene is agaV [H]

Identifier: 59714186

GI number: 59714186

Start: 1126840

End: 1127340

Strand: Reverse

Name: agaV [H]

Synonym: VF_A1003

Alternate gene names: 59714186

Gene position: 1127340-1126840 (Counterclockwise)

Preceding gene: 59714187

Following gene: 59714185

Centisome position: 84.74

GC content: 40.92

Gene sequence:

>501_bases
ATGACTGGACCACAAATCGTTTGGACGCGTATTGATGAGCGTTTACTGCATGGACAAATTCGAATTACTTGGGGAAAACA
TTCCGAAGCTAATTTGATTCTTGTTGCTAATGATGAAGCTGCTGAGGGCCCTAATGCTGCGTTTATGCAAGCAGGCATGA
AAGCCTCTGCAGGCGGTGAATATGCCGTGCGTTTCTTTTCAATTCAAAAAACCATTGATGTGATTCATAAAGCATCGCCA
AAACAGAAGATTTTTATCTTATGTAATAACCCTACTGACGTTGCTCGTTTGGTAGAAGGCGGCGTTCCAATTACACATTG
TAATGTAGGCAATATGCATTACCACGATGGTAAACGTCAAATTGCGAAAACCGTTTCTGTAGATAAAACCGATATTTTAG
CGTTTGAAAAAATGGTGGAAAAGGGCGTGACATGCACGGTTCAAAATACACCAGATCAAACACCAATTAACGTTCTTGAA
CTAGCAAAAACAGCAGCCTAG

Upstream 100 bases:

>100_bases
ATACTCCTGACAACCCGTGCCCTACAGGTGAAGTTAATCGTGTTGTTCAAGGCGTCAATATTCATACTTTTAATAATAAA
GATTAAAGCAGGGAAATATT

Downstream 100 bases:

>100_bases
GTAGGTACTTATGTTATTTGAAGCAAGTTTAGTGGCAGTGTGGGCATTCTTCTGTGGTATCGATAAATACGATGTCGCAT
TGAATATCCATAGACCACTT

Product: N-acetylgalactosamine-specific enzyme IIB component of PTS

Products: NA

Alternate protein names: EIIB-Aga'; PTS system N-acetylgalactosamine-specific EIIB component 2 [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTGPQIVWTRIDERLLHGQIRITWGKHSEANLILVANDEAAEGPNAAFMQAGMKASAGGEYAVRFFSIQKTIDVIHKASP
KQKIFILCNNPTDVARLVEGGVPITHCNVGNMHYHDGKRQIAKTVSVDKTDILAFEKMVEKGVTCTVQNTPDQTPINVLE
LAKTAA

Sequences:

>Translated_166_residues
MTGPQIVWTRIDERLLHGQIRITWGKHSEANLILVANDEAAEGPNAAFMQAGMKASAGGEYAVRFFSIQKTIDVIHKASP
KQKIFILCNNPTDVARLVEGGVPITHCNVGNMHYHDGKRQIAKTVSVDKTDILAFEKMVEKGVTCTVQNTPDQTPINVLE
LAKTAA
>Mature_165_residues
TGPQIVWTRIDERLLHGQIRITWGKHSEANLILVANDEAAEGPNAAFMQAGMKASAGGEYAVRFFSIQKTIDVIHKASPK
QKIFILCNNPTDVARLVEGGVPITHCNVGNMHYHDGKRQIAKTVSVDKTDILAFEKMVEKGVTCTVQNTPDQTPINVLEL
AKTAA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3444

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI87082217, Length=158, Percent_Identity=50, Blast_Score=160, Evalue=3e-41,
Organism=Escherichia coli, GI1789527, Length=151, Percent_Identity=43.7086092715232, Blast_Score=126, Evalue=6e-31,
Organism=Escherichia coli, GI1788120, Length=155, Percent_Identity=35.4838709677419, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004720
- InterPro:   IPR018455 [H]

Pfam domain/function: PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 18164; Mature: 18033

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS51101 PTS_EIIB_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPQIVWTRIDERLLHGQIRITWGKHSEANLILVANDEAAEGPNAAFMQAGMKASAGGE
CCCCEEEEEHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCC
YAVRFFSIQKTIDVIHKASPKQKIFILCNNPTDVARLVEGGVPITHCNVGNMHYHDGKRQ
EEEEEEEHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCEEEECCHHH
IAKTVSVDKTDILAFEKMVEKGVTCTVQNTPDQTPINVLELAKTAA
HHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TGPQIVWTRIDERLLHGQIRITWGKHSEANLILVANDEAAEGPNAAFMQAGMKASAGGE
CCCEEEEEHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCC
YAVRFFSIQKTIDVIHKASPKQKIFILCNNPTDVARLVEGGVPITHCNVGNMHYHDGKRQ
EEEEEEEHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCEEEECCHHH
IAKTVSVDKTDILAFEKMVEKGVTCTVQNTPDQTPINVLELAKTAA
HHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]