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The map label for this gene is cfa [H]

Identifier: 59713943

GI number: 59713943

Start: 856484

End: 857740

Strand: Reverse

Name: cfa [H]

Synonym: VF_A0760

Alternate gene names: 59713943

Gene position: 857740-856484 (Counterclockwise)

Preceding gene: 59713944

Following gene: 59713942

Centisome position: 64.48

GC content: 38.42

Gene sequence:

>1257_bases
ATGTCTAATAATCAAATCAATTCTGTTTCGATAGAAAATCAACAAGTAGAACCTGTAAGTTGGATTGATGGTCTGGCAAG
AAAGGTGTTAATTGACTACTTAGGAAAAATGTCTCAAGCATCTTTAACAATTTACGATCCAATTGGCCAAGTCACTTTAG
GAAATCCAGATGCAACGTTAGAAGCCGTTGTGGAGATTCATAATACGCAAGCGTATCGAAAAATTTTGTTCGGTGGTGGT
ATCGGTGCCAGCGAAGCCTATGTTGCTGGATGGTGGACAAGTCCGAACTTAACCAAAGTGATTCAAGTGTTAGGTCGTGA
GCAGGGCGTGTTAGACAGAGTTGAAAACAGTTTTAGTAAAATTATCCAATTTTTTGATTTGTTAAATCATAAACGCAATA
AAAATACTGAGCATGGATCGAAGAAAAACATACTGGCTCATTATGATTTAGGGAATGAAATGTATAAAACGTTCCTTGAT
AAAGAAATGCTGTATTCAAGTGCCATTTATCCACATCAAGAAGCCAATTTGGAAGAAGCTCAGTTATTTAAGTTACAAAC
CATTTGTGAGCGTTTGGAGCTAAAACCCGGTGAAACTCTTCTTGAGATCGGAACAGGCTGGGGAGCATTAGCCATTTATG
CTGCACAGAATTATGGTGTAAAAGTCACAACCACAACCATATCAGACGCTCAATACGAGTATGCCGAGCAGCGAGTGAAA
CAGTTGGGTTTGGAAGATTCAATTACCTTGTTAAAACAAGATTACCGTACGTTAGAAGGTCAATACGACAAGTTAGTGTC
GATTGAAATGATAGAAGCAGTAGGACACGAATATTTAAGCACTTTCTTTGATGTGTGTAGCCAGCATTTAAAGCCGGAAG
GAAAGATGCTTATTCAAGCAATTACCATCTCTGACCAACGTTATGACAAATACCGTAAGAGTGTTGATTTTATTCAGCGA
TACATTTTCCCTGGTGGGTGTTTACCTTCAGTGAGTGTCATGGCAAATAAAGTGGCTGAGAACACGGATATGGTGATCAC
TTCATTGCATGATATTGGGTTGGATTACGCCAAAACATTGAATCATTGGTATCAACGTTTTGATAAATCTGCCGGTGAGT
TAAAAGAGATGGGATATGGTGATGACTTTATTCGTCTTTGGAAATTCTATTTATGTTATTGCGAGGGTGGATTTCTTGAA
AGAAAAATCAGTACTGTTCACCTTGTTGCCGCAAAACCACAACATGGTGTTGTTTAA

Upstream 100 bases:

>100_bases
TGATGACCGTAAAGATAGTATATGGAATTTACTGGCAGGCACTGAAATTATGCTTAAAACGAATACCGTTTGTGCCTCAT
CCAGAAAAGTAGGGGGAACC

Downstream 100 bases:

>100_bases
GTCCATTGATATAGATTGTTAGTAAAGTTTTTTGCAAGTGATTTTTATAGATTAATGTTTGCAAATTATTGTTTAGGAGG
CTGCCATGCAACGTTATTTC

Product: cyclopropane fatty acyl phospholipid synthase (unsaturated-phospholipid methyltransferase)

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSNNQINSVSIENQQVEPVSWIDGLARKVLIDYLGKMSQASLTIYDPIGQVTLGNPDATLEAVVEIHNTQAYRKILFGGG
IGASEAYVAGWWTSPNLTKVIQVLGREQGVLDRVENSFSKIIQFFDLLNHKRNKNTEHGSKKNILAHYDLGNEMYKTFLD
KEMLYSSAIYPHQEANLEEAQLFKLQTICERLELKPGETLLEIGTGWGALAIYAAQNYGVKVTTTTISDAQYEYAEQRVK
QLGLEDSITLLKQDYRTLEGQYDKLVSIEMIEAVGHEYLSTFFDVCSQHLKPEGKMLIQAITISDQRYDKYRKSVDFIQR
YIFPGGCLPSVSVMANKVAENTDMVITSLHDIGLDYAKTLNHWYQRFDKSAGELKEMGYGDDFIRLWKFYLCYCEGGFLE
RKISTVHLVAAKPQHGVV

Sequences:

>Translated_418_residues
MSNNQINSVSIENQQVEPVSWIDGLARKVLIDYLGKMSQASLTIYDPIGQVTLGNPDATLEAVVEIHNTQAYRKILFGGG
IGASEAYVAGWWTSPNLTKVIQVLGREQGVLDRVENSFSKIIQFFDLLNHKRNKNTEHGSKKNILAHYDLGNEMYKTFLD
KEMLYSSAIYPHQEANLEEAQLFKLQTICERLELKPGETLLEIGTGWGALAIYAAQNYGVKVTTTTISDAQYEYAEQRVK
QLGLEDSITLLKQDYRTLEGQYDKLVSIEMIEAVGHEYLSTFFDVCSQHLKPEGKMLIQAITISDQRYDKYRKSVDFIQR
YIFPGGCLPSVSVMANKVAENTDMVITSLHDIGLDYAKTLNHWYQRFDKSAGELKEMGYGDDFIRLWKFYLCYCEGGFLE
RKISTVHLVAAKPQHGVV
>Mature_417_residues
SNNQINSVSIENQQVEPVSWIDGLARKVLIDYLGKMSQASLTIYDPIGQVTLGNPDATLEAVVEIHNTQAYRKILFGGGI
GASEAYVAGWWTSPNLTKVIQVLGREQGVLDRVENSFSKIIQFFDLLNHKRNKNTEHGSKKNILAHYDLGNEMYKTFLDK
EMLYSSAIYPHQEANLEEAQLFKLQTICERLELKPGETLLEIGTGWGALAIYAAQNYGVKVTTTTISDAQYEYAEQRVKQ
LGLEDSITLLKQDYRTLEGQYDKLVSIEMIEAVGHEYLSTFFDVCSQHLKPEGKMLIQAITISDQRYDKYRKSVDFIQRY
IFPGGCLPSVSVMANKVAENTDMVITSLHDIGLDYAKTLNHWYQRFDKSAGELKEMGYGDDFIRLWKFYLCYCEGGFLER
KISTVHLVAAKPQHGVV

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=359, Percent_Identity=35.933147632312, Blast_Score=214, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI133904226, Length=424, Percent_Identity=36.0849056603774, Blast_Score=236, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47379; Mature: 47247

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNQINSVSIENQQVEPVSWIDGLARKVLIDYLGKMSQASLTIYDPIGQVTLGNPDATL
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHH
EAVVEIHNTQAYRKILFGGGIGASEAYVAGWWTSPNLTKVIQVLGREQGVLDRVENSFSK
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
IIQFFDLLNHKRNKNTEHGSKKNILAHYDLGNEMYKTFLDKEMLYSSAIYPHQEANLEEA
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
QLFKLQTICERLELKPGETLLEIGTGWGALAIYAAQNYGVKVTTTTISDAQYEYAEQRVK
HHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHHHHH
QLGLEDSITLLKQDYRTLEGQYDKLVSIEMIEAVGHEYLSTFFDVCSQHLKPEGKMLIQA
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ITISDQRYDKYRKSVDFIQRYIFPGGCLPSVSVMANKVAENTDMVITSLHDIGLDYAKTL
EECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHH
NHWYQRFDKSAGELKEMGYGDDFIRLWKFYLCYCEGGFLERKISTVHLVAAKPQHGVV
HHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCEEEEEEECCCCCCC
>Mature Secondary Structure 
SNNQINSVSIENQQVEPVSWIDGLARKVLIDYLGKMSQASLTIYDPIGQVTLGNPDATL
CCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHH
EAVVEIHNTQAYRKILFGGGIGASEAYVAGWWTSPNLTKVIQVLGREQGVLDRVENSFSK
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
IIQFFDLLNHKRNKNTEHGSKKNILAHYDLGNEMYKTFLDKEMLYSSAIYPHQEANLEEA
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
QLFKLQTICERLELKPGETLLEIGTGWGALAIYAAQNYGVKVTTTTISDAQYEYAEQRVK
HHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHHHHH
QLGLEDSITLLKQDYRTLEGQYDKLVSIEMIEAVGHEYLSTFFDVCSQHLKPEGKMLIQA
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ITISDQRYDKYRKSVDFIQRYIFPGGCLPSVSVMANKVAENTDMVITSLHDIGLDYAKTL
EECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHH
NHWYQRFDKSAGELKEMGYGDDFIRLWKFYLCYCEGGFLERKISTVHLVAAKPQHGVV
HHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]