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The map label for this gene is gltS [H]

Identifier: 59713665

GI number: 59713665

Start: 554294

End: 555517

Strand: Reverse

Name: gltS [H]

Synonym: VF_A0482

Alternate gene names: 59713665

Gene position: 555517-554294 (Counterclockwise)

Preceding gene: 59713666

Following gene: 59713654

Centisome position: 41.76

GC content: 36.93

Gene sequence:

>1224_bases
ATGACAAACTCACTATCAATCGGCGCATTAGAATCATTTCTAATAGCAATCGCTGTGCTTTTTCTGGGTCATTTCATCAA
CTCAAAAATTGACCTTTTCAAAAAATATAATATCCCTGAGCCTATCGTTGGGGGATTAATTGTCGCCTTTGCAATTACGG
CTTTGCATTTTCAAGGAATTAGCCTTGAGTTTTCTCTGCCACTTCAAAATACCTTCATGCTAATGTTTTTTAGTACCGTT
GGTCTTGCAGCAAATTACACTCAATTGCTTAAAGGTGGCACTAAAGTCTTTCTATTTTTAGCTGTCGCATCGTTTTATAT
CATCATACAAAATGCCGTAGGTGTTGGTCTTGCCTCTGCTATGGGTTTAGACCCACTACTAGGCTTAATTGCAGGCTCTA
TTACTTTATCTGGCGGGCACGGTACAGGTGCAGCTTGGTCACAAACCTTTGCCGATGCTTATCAATTAAATACGCTTGAA
CTTGCAATGGCGTCAGCTACGTTTGGTCTGATTATGGGTGGTTTAATTGGTAGCCCTATCGCACAACGATTAATTCAAAA
ACATAAATTAGAATCTGAATACGGCGCTGGTACAAATACTCATGACCGCTTTCCTGAGCTAATTACTTATAACGAACGTG
AAGAAGACAAAGTGACAGCTAAAAAAGTCATTGAAATCTTATTCATCTTGCTTATCTGTGTTACCGGCTCTAAGCATTTA
AGTAATTTTGTAAACAGTTTCGATATTGCTTGGCTTAAAATTCCTGATTTTGTTTATGCGTTATTTATTGGTGTTTTCAT
TACTAATATTTGTGAAGTAACAAAAGTTAAAAAGATAGATAATGAAACCGTAGATATCCTTGGGACCGTTTCTTTGTCTC
TATTTTTAGCAATGGCGCTAATGAGTTTAAAACTATGGAACATCTTTGATCTTGCGATTCCATTTTTAATTATCTTAACG
ATTCAAACGATTGTTTTAGCCCTGTTCTCTTATTTCATTACTTTTAGAGTCATGGGTTCAAATTATGATGCTGCAGTTAT
GGTTGGCGGACATTGTGGATTTGGACTTGGAGCTACACCAACAGCAGTTATGAACATGGGTTCTTTAGTATCTCGCTTTG
GACCCTCACCTCAAGCATTCATGGTGGTTCCTATTGTAGGTGCATTCTTCATTGATATTACGAACTTAATTATCTTACAA
GCTTATATTAGCTTTATTGGATAA

Upstream 100 bases:

>100_bases
TTATGACAGTGAATATTTATAGTGACATTATCAATAACTTGGCATAATCTCGATCTTTCCCGTCACACCTCTTGGTTTGA
TATATTTATTTCGAGCTATT

Downstream 100 bases:

>100_bases
ATAAATCGGTAAATAAAAAAGCTATAAGGCACCACGCCTTATAGCTTTATCTTCATCACTACAATTTAAACTGCTCTACG
TTTTTCGACAAATTAGAAAT

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTNSLSIGALESFLIAIAVLFLGHFINSKIDLFKKYNIPEPIVGGLIVAFAITALHFQGISLEFSLPLQNTFMLMFFSTV
GLAANYTQLLKGGTKVFLFLAVASFYIIIQNAVGVGLASAMGLDPLLGLIAGSITLSGGHGTGAAWSQTFADAYQLNTLE
LAMASATFGLIMGGLIGSPIAQRLIQKHKLESEYGAGTNTHDRFPELITYNEREEDKVTAKKVIEILFILLICVTGSKHL
SNFVNSFDIAWLKIPDFVYALFIGVFITNICEVTKVKKIDNETVDILGTVSLSLFLAMALMSLKLWNIFDLAIPFLIILT
IQTIVLALFSYFITFRVMGSNYDAAVMVGGHCGFGLGATPTAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDITNLIILQ
AYISFIG

Sequences:

>Translated_407_residues
MTNSLSIGALESFLIAIAVLFLGHFINSKIDLFKKYNIPEPIVGGLIVAFAITALHFQGISLEFSLPLQNTFMLMFFSTV
GLAANYTQLLKGGTKVFLFLAVASFYIIIQNAVGVGLASAMGLDPLLGLIAGSITLSGGHGTGAAWSQTFADAYQLNTLE
LAMASATFGLIMGGLIGSPIAQRLIQKHKLESEYGAGTNTHDRFPELITYNEREEDKVTAKKVIEILFILLICVTGSKHL
SNFVNSFDIAWLKIPDFVYALFIGVFITNICEVTKVKKIDNETVDILGTVSLSLFLAMALMSLKLWNIFDLAIPFLIILT
IQTIVLALFSYFITFRVMGSNYDAAVMVGGHCGFGLGATPTAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDITNLIILQ
AYISFIG
>Mature_406_residues
TNSLSIGALESFLIAIAVLFLGHFINSKIDLFKKYNIPEPIVGGLIVAFAITALHFQGISLEFSLPLQNTFMLMFFSTVG
LAANYTQLLKGGTKVFLFLAVASFYIIIQNAVGVGLASAMGLDPLLGLIAGSITLSGGHGTGAAWSQTFADAYQLNTLEL
AMASATFGLIMGGLIGSPIAQRLIQKHKLESEYGAGTNTHDRFPELITYNEREEDKVTAKKVIEILFILLICVTGSKHLS
NFVNSFDIAWLKIPDFVYALFIGVFITNICEVTKVKKIDNETVDILGTVSLSLFLAMALMSLKLWNIFDLAIPFLIILTI
QTIVLALFSYFITFRVMGSNYDAAVMVGGHCGFGLGATPTAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDITNLIILQA
YISFIG

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=388, Percent_Identity=47.1649484536082, Blast_Score=301, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 44024; Mature: 43892

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSLSIGALESFLIAIAVLFLGHFINSKIDLFKKYNIPEPIVGGLIVAFAITALHFQGI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
SLEFSLPLQNTFMLMFFSTVGLAANYTQLLKGGTKVFLFLAVASFYIIIQNAVGVGLASA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLDPLLGLIAGSITLSGGHGTGAAWSQTFADAYQLNTLELAMASATFGLIMGGLIGSPI
CCHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
AQRLIQKHKLESEYGAGTNTHDRFPELITYNEREEDKVTAKKVIEILFILLICVTGSKHL
HHHHHHHHHCCHHCCCCCCCHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
SNFVNSFDIAWLKIPDFVYALFIGVFITNICEVTKVKKIDNETVDILGTVSLSLFLAMAL
HHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MSLKLWNIFDLAIPFLIILTIQTIVLALFSYFITFRVMGSNYDAAVMVGGHCGFGLGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCH
TAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDITNLIILQAYISFIG
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TNSLSIGALESFLIAIAVLFLGHFINSKIDLFKKYNIPEPIVGGLIVAFAITALHFQGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
SLEFSLPLQNTFMLMFFSTVGLAANYTQLLKGGTKVFLFLAVASFYIIIQNAVGVGLASA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLDPLLGLIAGSITLSGGHGTGAAWSQTFADAYQLNTLELAMASATFGLIMGGLIGSPI
CCHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
AQRLIQKHKLESEYGAGTNTHDRFPELITYNEREEDKVTAKKVIEILFILLICVTGSKHL
HHHHHHHHHCCHHCCCCCCCHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
SNFVNSFDIAWLKIPDFVYALFIGVFITNICEVTKVKKIDNETVDILGTVSLSLFLAMAL
HHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MSLKLWNIFDLAIPFLIILTIQTIVLALFSYFITFRVMGSNYDAAVMVGGHCGFGLGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCH
TAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDITNLIILQAYISFIG
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]