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The map label for this gene is kefG [H]

Identifier: 59713444

GI number: 59713444

Start: 293592

End: 294209

Strand: Reverse

Name: kefG [H]

Synonym: VF_A0261

Alternate gene names: 59713444

Gene position: 294209-293592 (Counterclockwise)

Preceding gene: 59713445

Following gene: 59713443

Centisome position: 22.12

GC content: 36.73

Gene sequence:

>618_bases
ATGACAAGCCCGGCTAAAAAAGTACTGATTTTATTCGCTCATCCTTCTCAACACCGCTCTGAAGTTAATGTGGCATTAAT
TAAACAAGCTAAAAAAATTGAGCATGTCACTGTTGTCGATTTGTACCATGATTATCCAAAATTCAATATTGATATCGATA
AAGAACAAAAACAACTTTTAGATCATGATGTTATTATCTTTCAATTTCCGCTTTATTGGTACTCAACCCCAGCTATTTTA
AAAGAGTGGCAAGATATGGTTTTAGAGTACGGTTTTGCTTATGGTACAGACGGTAATGCACTAAAAGGAAAAACCTTTCT
ATGTGCTATCACTGCTGGAGGTAAGGAAGAGGCTTATCAAACCAATGGATATAATCAATTCACTATCCGTGAACTCCTAC
ATCCGCTTGAACAGATGGCCTCACTAACTCATATGGAGTATATCGCTCCATTAGTGCTATTTGGCGCTAGAACCGCGTTA
GAAGATGACCGTATTGAAAGACATACTGAGCGCTTTAAAGTCTTACTGTCCGCATTAATTGAAAATCGTGTTGATACTGA
GGTAGCAAAAACGTTACCCAAACTAAACCACTCATTCGATAAATTTATTAAGGAATAA

Upstream 100 bases:

>100_bases
TAATTTATGCAAAATTTACAAGCTGAAAAACATTTCTATTATATTTTCTTGCTATCATGTAAACATAAATACAATAACTT
AAATAATACAAAGAGGTTTT

Downstream 100 bases:

>100_bases
AAGCATTATGACTGGATATTTTTTACAAGCTTTTATCTACCTTGTTGCTGCTGTTATTGCTGTACCAATCGCTAAACGTC
TAGGACTTGGTTCTGTTCTT

Product: modulator of glutathione-dependent potassium efflux system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTSPAKKVLILFAHPSQHRSEVNVALIKQAKKIEHVTVVDLYHDYPKFNIDIDKEQKQLLDHDVIIFQFPLYWYSTPAIL
KEWQDMVLEYGFAYGTDGNALKGKTFLCAITAGGKEEAYQTNGYNQFTIRELLHPLEQMASLTHMEYIAPLVLFGARTAL
EDDRIERHTERFKVLLSALIENRVDTEVAKTLPKLNHSFDKFIKE

Sequences:

>Translated_205_residues
MTSPAKKVLILFAHPSQHRSEVNVALIKQAKKIEHVTVVDLYHDYPKFNIDIDKEQKQLLDHDVIIFQFPLYWYSTPAIL
KEWQDMVLEYGFAYGTDGNALKGKTFLCAITAGGKEEAYQTNGYNQFTIRELLHPLEQMASLTHMEYIAPLVLFGARTAL
EDDRIERHTERFKVLLSALIENRVDTEVAKTLPKLNHSFDKFIKE
>Mature_204_residues
TSPAKKVLILFAHPSQHRSEVNVALIKQAKKIEHVTVVDLYHDYPKFNIDIDKEQKQLLDHDVIIFQFPLYWYSTPAILK
EWQDMVLEYGFAYGTDGNALKGKTFLCAITAGGKEEAYQTNGYNQFTIRELLHPLEQMASLTHMEYIAPLVLFGARTALE
DDRIERHTERFKVLLSALIENRVDTEVAKTLPKLNHSFDKFIKE

Specific function: Required for full activity of kefB [H]

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=200, Percent_Identity=34.5, Blast_Score=91, Evalue=6e-19,
Organism=Escherichia coli, GI1789750, Length=157, Percent_Identity=46.4968152866242, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1786231, Length=166, Percent_Identity=36.7469879518072, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787129, Length=195, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 23683; Mature: 23551

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPAKKVLILFAHPSQHRSEVNVALIKQAKKIEHVTVVDLYHDYPKFNIDIDKEQKQLL
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECHHHHHHH
DHDVIIFQFPLYWYSTPAILKEWQDMVLEYGFAYGTDGNALKGKTFLCAITAGGKEEAYQ
CCCEEEEEECHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHC
TNGYNQFTIRELLHPLEQMASLTHMEYIAPLVLFGARTALEDDRIERHTERFKVLLSALI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ENRVDTEVAKTLPKLNHSFDKFIKE
HCCCHHHHHHHHHHHCHHHHHHHCC
>Mature Secondary Structure 
TSPAKKVLILFAHPSQHRSEVNVALIKQAKKIEHVTVVDLYHDYPKFNIDIDKEQKQLL
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECHHHHHHH
DHDVIIFQFPLYWYSTPAILKEWQDMVLEYGFAYGTDGNALKGKTFLCAITAGGKEEAYQ
CCCEEEEEECHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHC
TNGYNQFTIRELLHPLEQMASLTHMEYIAPLVLFGARTALEDDRIERHTERFKVLLSALI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ENRVDTEVAKTLPKLNHSFDKFIKE
HCCCHHHHHHHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA