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The map label for this gene is yjeK [H]

Identifier: 59712946

GI number: 59712946

Start: 2627974

End: 2628996

Strand: Direct

Name: yjeK [H]

Synonym: VF_2339

Alternate gene names: 59712946

Gene position: 2627974-2628996 (Clockwise)

Preceding gene: 59712944

Following gene: 59712950

Centisome position: 90.7

GC content: 39.0

Gene sequence:

>1023_bases
ATGTCACACATGATAACCCGAAATGACGCTCCTGTTGAGCAAAACTGGCTCAAAGAACTAGCTAATGCGATCTCTAACCC
TCATCAACTACTTTCAACACTTGGTATTGATAGCGCTCCGTGGGAAAAAGGATTGGAAGCGAAAAAGTTATTTGCGTTAC
GTGTGCCGACAAGTTTTGTCGATAGAATGGAATTTGGCAACCCTTTTGATCCTTTATTACGCCAAGTATTGCCTTTAGAT
CAAGAATTCGAGGTACATGAGGGATATTCGAACGATCCTTTAGAGGAGCAAGACAACCAACAACTGGGTTTATTGCATAA
GTATAAAAACCGAGTTCTATTGATTGTTAAAGGGGGATGCGCTGTTAATTGTCGCTACTGCTTCCGCCGTCACTTTCCAT
ATCAAGACAATAAAGGCAGCAAAACTATTTGGCAAGAGTCCATTGATTACATCGCCAACCACCCAGAAATAAATGAAGTT
ATTTTCTCTGGCGGTGATCCATTAATGGCAAAAGATCACGAACTTCAATGGTTAATTGACCATATTGAAGCAATTCCGCA
TATCAAGCGCCTTCGTATCCACTCTCGCTTGCCGGTGGTAATACCAAACCGTATTACCGATACGTTGTGTCAGCTATTTA
CAAAAACACGCTTACAAATCATTCTAGTGACTCATATCAATCATGCTAATGAAATTAACCAAGAACTCATCAGTAGTATG
CACAAACTGAAGCTTGCTCATGTCACTCTATTAAATCAAAGCGTGTTATTAAAAGGCGTTAATGATAATGCAGATACATT
AACTCAATTAAGTGAAGCGTTATTCGATGCGGGTATTTTGCCTTATTACCTTCATGTATTAGATAAAGTCCAAGGGGCTG
CTCATTTCTTTATTTCTGACGAAAAAGCCAAACAGTTAATGAGTGAACTGATAGAAAATGTATCTGGTTACCTTGTTCCT
ACATTAGCTAGAGAGATTGGTGGTAGAAAAAGCAAAACACCTCTCGACTTATATTTGGAATAA

Upstream 100 bases:

>100_bases
GAGCATGGCTCATTATCTAACATAAATTTCAAACCGCCTTTGAATTCATTGGTACTTACTGACGCCATGATTTCCTCTTA
ACATCGTTGAGTTATAAATA

Downstream 100 bases:

>100_bases
TTACAGGCATAAAAAAACCGAAGCACTCGCTTCGGTTTTTTGTGTCTAGAATTCAATTCTAAATTAGAATAACTCTTCAG
CTACTTTGTATAGCTCAAGT

Product: lysine aminomutase

Products: (3S)-3,6-diaminohexanoate

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSHMITRNDAPVEQNWLKELANAISNPHQLLSTLGIDSAPWEKGLEAKKLFALRVPTSFVDRMEFGNPFDPLLRQVLPLD
QEFEVHEGYSNDPLEEQDNQQLGLLHKYKNRVLLIVKGGCAVNCRYCFRRHFPYQDNKGSKTIWQESIDYIANHPEINEV
IFSGGDPLMAKDHELQWLIDHIEAIPHIKRLRIHSRLPVVIPNRITDTLCQLFTKTRLQIILVTHINHANEINQELISSM
HKLKLAHVTLLNQSVLLKGVNDNADTLTQLSEALFDAGILPYYLHVLDKVQGAAHFFISDEKAKQLMSELIENVSGYLVP
TLAREIGGRKSKTPLDLYLE

Sequences:

>Translated_340_residues
MSHMITRNDAPVEQNWLKELANAISNPHQLLSTLGIDSAPWEKGLEAKKLFALRVPTSFVDRMEFGNPFDPLLRQVLPLD
QEFEVHEGYSNDPLEEQDNQQLGLLHKYKNRVLLIVKGGCAVNCRYCFRRHFPYQDNKGSKTIWQESIDYIANHPEINEV
IFSGGDPLMAKDHELQWLIDHIEAIPHIKRLRIHSRLPVVIPNRITDTLCQLFTKTRLQIILVTHINHANEINQELISSM
HKLKLAHVTLLNQSVLLKGVNDNADTLTQLSEALFDAGILPYYLHVLDKVQGAAHFFISDEKAKQLMSELIENVSGYLVP
TLAREIGGRKSKTPLDLYLE
>Mature_339_residues
SHMITRNDAPVEQNWLKELANAISNPHQLLSTLGIDSAPWEKGLEAKKLFALRVPTSFVDRMEFGNPFDPLLRQVLPLDQ
EFEVHEGYSNDPLEEQDNQQLGLLHKYKNRVLLIVKGGCAVNCRYCFRRHFPYQDNKGSKTIWQESIDYIANHPEINEVI
FSGGDPLMAKDHELQWLIDHIEAIPHIKRLRIHSRLPVVIPNRITDTLCQLFTKTRLQIILVTHINHANEINQELISSMH
KLKLAHVTLLNQSVLLKGVNDNADTLTQLSEALFDAGILPYYLHVLDKVQGAAHFFISDEKAKQLMSELIENVSGYLVPT
LAREIGGRKSKTPLDLYLE

Specific function: With YjeA might be involved in the post-translational modification of elongation factor P (EF-P) [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=342, Percent_Identity=64.6198830409357, Blast_Score=460, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022462
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: 5.4.3.2

Molecular weight: Translated: 38843; Mature: 38712

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHMITRNDAPVEQNWLKELANAISNPHQLLSTLGIDSAPWEKGLEAKKLFALRVPTSFV
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHCCCHHHEEEEECCHHHH
DRMEFGNPFDPLLRQVLPLDQEFEVHEGYSNDPLEEQDNQQLGLLHKYKNRVLLIVKGGC
HHHHCCCCHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCC
AVNCRYCFRRHFPYQDNKGSKTIWQESIDYIANHPEINEVIFSGGDPLMAKDHELQWLID
EEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCHHHHHHH
HIEAIPHIKRLRIHSRLPVVIPNRITDTLCQLFTKTRLQIILVTHINHANEINQELISSM
HHHHCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHH
HKLKLAHVTLLNQSVLLKGVNDNADTLTQLSEALFDAGILPYYLHVLDKVQGAAHFFISD
HHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHEEEECC
EKAKQLMSELIENVSGYLVPTLAREIGGRKSKTPLDLYLE
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure 
SHMITRNDAPVEQNWLKELANAISNPHQLLSTLGIDSAPWEKGLEAKKLFALRVPTSFV
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHCCCHHHEEEEECCHHHH
DRMEFGNPFDPLLRQVLPLDQEFEVHEGYSNDPLEEQDNQQLGLLHKYKNRVLLIVKGGC
HHHHCCCCHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCC
AVNCRYCFRRHFPYQDNKGSKTIWQESIDYIANHPEINEVIFSGGDPLMAKDHELQWLID
EEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCHHHHHHH
HIEAIPHIKRLRIHSRLPVVIPNRITDTLCQLFTKTRLQIILVTHINHANEINQELISSM
HHHHCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHH
HKLKLAHVTLLNQSVLLKGVNDNADTLTQLSEALFDAGILPYYLHVLDKVQGAAHFFISD
HHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHEEEECC
EKAKQLMSELIENVSGYLVPTLAREIGGRKSKTPLDLYLE
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-lysine

Specific reaction: L-lysine = (3S)-3,6-diaminohexanoate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]