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The map label for this gene is argC

Identifier: 59712913

GI number: 59712913

Start: 2590892

End: 2591896

Strand: Reverse

Name: argC

Synonym: VF_2306

Alternate gene names: 59712913

Gene position: 2591896-2590892 (Counterclockwise)

Preceding gene: 59712916

Following gene: 59712912

Centisome position: 89.45

GC content: 39.3

Gene sequence:

>1005_bases
ATGTTGAAAACAGCCATTATTGGAGCGAGTGGATACACAGGAGCTGAATTAGCTCTGATGGTATTTAAGCATCCACACCT
TTCTTTATCGGGTTTATATGTTTCAGAAAACAGTCTAGATAAAGGAAAGGCGATCAGTGAATTGCATGGTTCATTAAAAG
GAATTGTTGATGAAGCATTACAGCCATTAGTTAATGTGAATCAAGCTGCTAAAGAGTGTGATGTTATTTTGCTAGCAACT
GCCCATGAAGTCAGTCATAACTTAGCAGCAACATTTTTAGAAAATGGCTGTGTAGTATTCGATTTATCTGGCGCTTTTCG
TGTGAAAAAAGAAGGCTTTTACAGTGAGTTCTATGGTTTTGAGCATCAATATGAAGCGTGGTTAGATAAAGCCGTTTATG
GTTTAGCTGAGTGGAATGCTGAAGCCATAGCGAAAGCACAATTGGTTGCTGTTCCTGGCTGTTATCCGACTGCGTCACAA
TTAGCACTAAAACCGTTAGTTAAATCTGAATTATTAGATAAGAATCAATGGCCTGTTATAAATGCAACTAGCGGGGTAAC
AGGAGCAGGACGTAAGGCAAGTTTAACCAGTTCTTTCTGTGAAGTGAGCTTACAACCCTATGGTGTGTTTAATCATCGTC
ACCAACCTGAAATTGCAGCTCATTTAGGTTGTGATGTGATTTTCACTCCTCATTTAGGTAATTTTAAGCGTGGTATTTTA
GCGACAATCACGACTAAATTAGCGAAAGGCGTGACAGAAAAAGAAATTCAAGAAGCGTTTGAAACGGCTTATACCCAAAC
GCCAGCGGTGCGTTTATTAGAAAACGAAATGCCCAAGATTCAATCGGTAGAGAAAACCCCTTTTTGCGATATTGGCTGGA
AAGTGCAAGGGGAGCATTTAATCGTCGTTTCTGCGATTGATAACTTGTTGAAAGGTGCATCAAGTCAAGCAATGCAATGC
ATTAATATTCGTTTTGGTTTTCCGGTATTAACCGCATTGATTTAA

Upstream 100 bases:

>100_bases
AATTGAGAGAAGGAAAGGATACCTTCAATATGGGCAACACTCACGTTACCCTGAATGGCTTTTCCCTTCAATAAGATTTA
AGAGATAAAAGGGACGAATT

Downstream 100 bases:

>100_bases
GGAAGAATAATAAATATGAATCAACGTCCATTGGTTATAAAGCTTGGTGGAGCAGTATTGTCTTCAATCGATACGCTCAC
GCTGTTATTTAAAACAATTT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLKTAIIGASGYTGAELALMVFKHPHLSLSGLYVSENSLDKGKAISELHGSLKGIVDEALQPLVNVNQAAKECDVILLAT
AHEVSHNLAATFLENGCVVFDLSGAFRVKKEGFYSEFYGFEHQYEAWLDKAVYGLAEWNAEAIAKAQLVAVPGCYPTASQ
LALKPLVKSELLDKNQWPVINATSGVTGAGRKASLTSSFCEVSLQPYGVFNHRHQPEIAAHLGCDVIFTPHLGNFKRGIL
ATITTKLAKGVTEKEIQEAFETAYTQTPAVRLLENEMPKIQSVEKTPFCDIGWKVQGEHLIVVSAIDNLLKGASSQAMQC
INIRFGFPVLTALI

Sequences:

>Translated_334_residues
MLKTAIIGASGYTGAELALMVFKHPHLSLSGLYVSENSLDKGKAISELHGSLKGIVDEALQPLVNVNQAAKECDVILLAT
AHEVSHNLAATFLENGCVVFDLSGAFRVKKEGFYSEFYGFEHQYEAWLDKAVYGLAEWNAEAIAKAQLVAVPGCYPTASQ
LALKPLVKSELLDKNQWPVINATSGVTGAGRKASLTSSFCEVSLQPYGVFNHRHQPEIAAHLGCDVIFTPHLGNFKRGIL
ATITTKLAKGVTEKEIQEAFETAYTQTPAVRLLENEMPKIQSVEKTPFCDIGWKVQGEHLIVVSAIDNLLKGASSQAMQC
INIRFGFPVLTALI
>Mature_334_residues
MLKTAIIGASGYTGAELALMVFKHPHLSLSGLYVSENSLDKGKAISELHGSLKGIVDEALQPLVNVNQAAKECDVILLAT
AHEVSHNLAATFLENGCVVFDLSGAFRVKKEGFYSEFYGFEHQYEAWLDKAVYGLAEWNAEAIAKAQLVAVPGCYPTASQ
LALKPLVKSELLDKNQWPVINATSGVTGAGRKASLTSSFCEVSLQPYGVFNHRHQPEIAAHLGCDVIFTPHLGNFKRGIL
ATITTKLAKGVTEKEIQEAFETAYTQTPAVRLLENEMPKIQSVEKTPFCDIGWKVQGEHLIVVSAIDNLLKGASSQAMQC
INIRFGFPVLTALI

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=334, Percent_Identity=61.9760479041916, Blast_Score=436, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6320913, Length=336, Percent_Identity=30.952380952381, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_VIBF1 (Q5E2E5)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205689.1
- ProteinModelPortal:   Q5E2E5
- SMR:   Q5E2E5
- STRING:   Q5E2E5
- GeneID:   3279414
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_2306
- NMPDR:   fig|312309.3.peg.2306
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q5E2E5
- ProtClustDB:   PRK00436
- BioCyc:   VFIS312309:VF2306-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36245; Mature: 36245

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS01224 ARGC; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 154-154

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTAIIGASGYTGAELALMVFKHPHLSLSGLYVSENSLDKGKAISELHGSLKGIVDEAL
CCCEEEEECCCCCCHHEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
QPLVNVNQAAKECDVILLATAHEVSHNLAATFLENGCVVFDLSGAFRVKKEGFYSEFYGF
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCHHHHCCC
EHQYEAWLDKAVYGLAEWNAEAIAKAQLVAVPGCYPTASQLALKPLVKSELLDKNQWPVI
CHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEE
NATSGVTGAGRKASLTSSFCEVSLQPYGVFNHRHQPEIAAHLGCDVIFTPHLGNFKRGIL
ECCCCCCCCCCCCHHHHHHHHEECCCCCCCCCCCCCCHHHHCCCCEEECCCCCCHHHHHH
ATITTKLAKGVTEKEIQEAFETAYTQTPAVRLLENEMPKIQSVEKTPFCDIGWKVQGEHL
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHCCCCCCCCCCCCEECCCEE
IVVSAIDNLLKGASSQAMQCINIRFGFPVLTALI
EEHHHHHHHHCCCCHHHEEEEEEEECHHHHHHCC
>Mature Secondary Structure
MLKTAIIGASGYTGAELALMVFKHPHLSLSGLYVSENSLDKGKAISELHGSLKGIVDEAL
CCCEEEEECCCCCCHHEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
QPLVNVNQAAKECDVILLATAHEVSHNLAATFLENGCVVFDLSGAFRVKKEGFYSEFYGF
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCHHHHCCC
EHQYEAWLDKAVYGLAEWNAEAIAKAQLVAVPGCYPTASQLALKPLVKSELLDKNQWPVI
CHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEE
NATSGVTGAGRKASLTSSFCEVSLQPYGVFNHRHQPEIAAHLGCDVIFTPHLGNFKRGIL
ECCCCCCCCCCCCHHHHHHHHEECCCCCCCCCCCCCCHHHHCCCCEEECCCCCCHHHHHH
ATITTKLAKGVTEKEIQEAFETAYTQTPAVRLLENEMPKIQSVEKTPFCDIGWKVQGEHL
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHCCCCCCCCCCCCEECCCEE
IVVSAIDNLLKGASSQAMQCINIRFGFPVLTALI
EEHHHHHHHHCCCCHHHEEEEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA