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The map label for this gene is argB

Identifier: 59712912

GI number: 59712912

Start: 2590094

End: 2590876

Strand: Reverse

Name: argB

Synonym: VF_2305

Alternate gene names: 59712912

Gene position: 2590876-2590094 (Counterclockwise)

Preceding gene: 59712913

Following gene: 59712911

Centisome position: 89.42

GC content: 41.38

Gene sequence:

>783_bases
ATGAATCAACGTCCATTGGTTATAAAGCTTGGTGGAGCAGTATTGTCTTCAATCGATACGCTCACGCTGTTATTTAAAAC
AATTTCAAATTATCAACAGCAAGCCAAGCGTTCTCTTATTATTGTTCATGGTGGTGGCTATCTTGTTGATGAGCTTATGG
CAAAGCTTCAATTAGAAACAATAAAAAAAGAGGGGTTACGAGTTACTCCAAAAGATCAGATTGGCTATATCACAGGTGCG
TTGGCTGGAACGGCAAATAAAATGCTACAGGGCCAAGCCATGAAAAATAACGTTAAGGCAATTGGCTTAAGTTTGGCTGA
TGGTGGTTTGTGTCAGATCACTCAATTAAACCCTGAATTAGGTAATGTCGGCTTAGCAACGGCTGGTGATGCAAAAGTAT
TAGAGGCGATTTTAGCAACTCAAGTAACGCCCATTATTAGCTCTATCGGTATTACGAATGATGGTGAATTAATGAATGTA
AATGCTGATCAAGCTGCGGTTGCAGTAGCGACAGCATTGGATGCTGATTTGGTTCTATTGTCAGACGTTCCCGGAGTGCT
AGATGCCGAAAAACAGCTGATTAAGAGTTTGGACTCAGCGCAAGCTGAAATGTTAATTCACCAAGCTGTTATTACCGATG
GCATGATAGTTAAAGTCCGTGCAGCATTGGATGCAGCTCAAGAATTAGGGCGAGCAATAGAAGTGGCTTCATGGCGCTCA
CCAGAAAAATTAGCTGAGTTGTTTATTGGAAACAGCATTGGCACACAATTTCAGCCTCAATAG

Upstream 100 bases:

>100_bases
TAACTTGTTGAAAGGTGCATCAAGTCAAGCAATGCAATGCATTAATATTCGTTTTGGTTTTCCGGTATTAACCGCATTGA
TTTAAGGAAGAATAATAAAT

Downstream 100 bases:

>100_bases
GCAATGTAATTTTAAGAATATAGTCGCCGCGAGTTGTGCGGTTCAAGGAGAATAGAATGAGTAAGAAAGTAGAAGTAAAC
AAGGTTGTTGTCGCATACTC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNQRPLVIKLGGAVLSSIDTLTLLFKTISNYQQQAKRSLIIVHGGGYLVDELMAKLQLETIKKEGLRVTPKDQIGYITGA
LAGTANKMLQGQAMKNNVKAIGLSLADGGLCQITQLNPELGNVGLATAGDAKVLEAILATQVTPIISSIGITNDGELMNV
NADQAAVAVATALDADLVLLSDVPGVLDAEKQLIKSLDSAQAEMLIHQAVITDGMIVKVRAALDAAQELGRAIEVASWRS
PEKLAELFIGNSIGTQFQPQ

Sequences:

>Translated_260_residues
MNQRPLVIKLGGAVLSSIDTLTLLFKTISNYQQQAKRSLIIVHGGGYLVDELMAKLQLETIKKEGLRVTPKDQIGYITGA
LAGTANKMLQGQAMKNNVKAIGLSLADGGLCQITQLNPELGNVGLATAGDAKVLEAILATQVTPIISSIGITNDGELMNV
NADQAAVAVATALDADLVLLSDVPGVLDAEKQLIKSLDSAQAEMLIHQAVITDGMIVKVRAALDAAQELGRAIEVASWRS
PEKLAELFIGNSIGTQFQPQ
>Mature_260_residues
MNQRPLVIKLGGAVLSSIDTLTLLFKTISNYQQQAKRSLIIVHGGGYLVDELMAKLQLETIKKEGLRVTPKDQIGYITGA
LAGTANKMLQGQAMKNNVKAIGLSLADGGLCQITQLNPELGNVGLATAGDAKVLEAILATQVTPIISSIGITNDGELMNV
NADQAAVAVATALDADLVLLSDVPGVLDAEKQLIKSLDSAQAEMLIHQAVITDGMIVKVRAALDAAQELGRAIEVASWRS
PEKLAELFIGNSIGTQFQPQ

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=253, Percent_Identity=55.7312252964427, Blast_Score=263, Evalue=7e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_VIBF1 (Q5E2E6)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205688.1
- HSSP:   P0A6C8
- ProteinModelPortal:   Q5E2E6
- SMR:   Q5E2E6
- STRING:   Q5E2E6
- GeneID:   3279433
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_2305
- NMPDR:   fig|312309.3.peg.2305
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- PhylomeDB:   Q5E2E6
- ProtClustDB:   PRK00942
- BioCyc:   VFIS312309:VF2305-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27390; Mature: 27390

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: BINDING 67-67 BINDING 159-159

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRPLVIKLGGAVLSSIDTLTLLFKTISNYQQQAKRSLIIVHGGGYLVDELMAKLQLET
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHH
IKKEGLRVTPKDQIGYITGALAGTANKMLQGQAMKNNVKAIGLSLADGGLCQITQLNPEL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEEEECCCCEEEEEECCCCC
GNVGLATAGDAKVLEAILATQVTPIISSIGITNDGELMNVNADQAAVAVATALDADLVLL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHCCCEEEE
SDVPGVLDAEKQLIKSLDSAQAEMLIHQAVITDGMIVKVRAALDAAQELGRAIEVASWRS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
PEKLAELFIGNSIGTQFQPQ
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNQRPLVIKLGGAVLSSIDTLTLLFKTISNYQQQAKRSLIIVHGGGYLVDELMAKLQLET
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHH
IKKEGLRVTPKDQIGYITGALAGTANKMLQGQAMKNNVKAIGLSLADGGLCQITQLNPEL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEEEECCCCEEEEEECCCCC
GNVGLATAGDAKVLEAILATQVTPIISSIGITNDGELMNVNADQAAVAVATALDADLVLL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHCCCEEEE
SDVPGVLDAEKQLIKSLDSAQAEMLIHQAVITDGMIVKVRAALDAAQELGRAIEVASWRS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
PEKLAELFIGNSIGTQFQPQ
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA