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The map label for this gene is mraY [H]

Identifier: 59712811

GI number: 59712811

Start: 2476223

End: 2477305

Strand: Reverse

Name: mraY [H]

Synonym: VF_2204

Alternate gene names: 59712811

Gene position: 2477305-2476223 (Counterclockwise)

Preceding gene: 59712812

Following gene: 59712810

Centisome position: 85.5

GC content: 40.35

Gene sequence:

>1083_bases
ATGATTATTTGGTTATCCAATTTTCTAGAGCAATATTTTCCATTTTTTCGCTTATTTGAATATTTAAGTTTTAGAGCCAT
CTTAAGCATTATCACGGCATTAACGATCTCTTTATGGATGGGACCAAAACTGATTGCTTGGTTGCAAAACCTTCAAATTG
GTCAAGTGGTACGTGATGACGGTCCTGAATCACATTTTAGTAAGCGTGGTACGCCAACGATGGGCGGCATCATGATTTTA
ACTGCAATTACAGTGACAGTGTTCTTGTGGGCAGATTTAACTAACCCTTATGTATGGGCTGTTATGTTTGTACTACTAGG
CTATGGTGCTGTTGGCTTTGTTGATGACTACCGTAAAGTTGTTCGTAAAAATACAGATGGTCTAATCGCTCGTTGGAAGT
ATTTTTGGCAATCTTCTATTGCGTTAGTTGTCGCTTTTGCTCTTTATGCTTACGGAAAAGATACGGCAGCAACGCAGTTA
GTTGTTCCTTTCTTTAAAGAAGTAATGCCTCAACTTGGTCTTGCTTATATTCTTCTTACCTACTTTGTTATCGTAGGAAC
CAGTAATGCGGTGAACTTAACCGATGGTCTTGATGGTCTTGCAATCATGCCTACGGTATTTGTTGCTGCAGGTTTTGCCT
TTATTGCTTGGGCAACAGGTAACGTGCAATTCGCAAACTACTTACATATTCCGCATATTCCGTTAGCGAGTGAGTTAGTG
GTTGTGTGTGCTGCGATTGTTGGTGCTGGTTTTGGTTTCTTATGGTTCAACACGTATCCAGCACAAGTATTTATGGGTGA
TGTAGGTTCACTGGCTCTTGGTGGAGCACTAGGTACGATTGCAGTGTTAGTTCGTCAAGAGTTCCTATTGGTTATCATGG
GTGGTGTATTCGTTGTTGAAACGTTATCGGTAATCTTACAAGTGGGTTCATACAAACTACGTGGTCAACGTATTTTCCGT
ATGGCACCAATTCATCACCATTACGAATTAAAAGGTTGGCCAGAGCCTCGCGTTATTGTGCGTTTCTGGATTATTTCTAT
GTTATTGGTTCTTATTGCATTAGCGACATTGAAGGTACGTTAA

Upstream 100 bases:

>100_bases
AATTACAATTAATTAAACATAATGAGGTTACCGTGTTAGTTAAAGGTGCCAACAGTTCACGAATGAGCGAAGTGGTTTCA
GCTCTTAAGGAGTGTCAGTA

Downstream 100 bases:

>100_bases
TATGAGTGGTTTTGGTGGTGTAAAAAATGTTGTAGTAGTTGGCTTAGGTATGACAGGTTTATCTGTTGTTAAGCATTTAC
TTAAGACTACCATAAGCGTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALTISLWMGPKLIAWLQNLQIGQVVRDDGPESHFSKRGTPTMGGIMIL
TAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSSIALVVAFALYAYGKDTAATQL
VVPFFKEVMPQLGLAYILLTYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPLASELV
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR

Sequences:

>Translated_360_residues
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALTISLWMGPKLIAWLQNLQIGQVVRDDGPESHFSKRGTPTMGGIMIL
TAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSSIALVVAFALYAYGKDTAATQL
VVPFFKEVMPQLGLAYILLTYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPLASELV
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR
>Mature_360_residues
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALTISLWMGPKLIAWLQNLQIGQVVRDDGPESHFSKRGTPTMGGIMIL
TAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSSIALVVAFALYAYGKDTAATQL
VVPFFKEVMPQLGLAYILLTYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPLASELV
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=80.5555555555556, Blast_Score=574, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 40108; Mature: 40108

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALTISLWMGPKLIAWLQNLQIGQVVRDD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCC
GPESHFSKRGTPTMGGIMILTAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSSIALVVAFALYAYGKDTAATQLVVPFFKEVMPQLGLAYILLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPLASELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEEEEECCCCCHHHHHH
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVE
HHHHHHHHCCCCEEHEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR
HHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALTISLWMGPKLIAWLQNLQIGQVVRDD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCC
GPESHFSKRGTPTMGGIMILTAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSSIALVVAFALYAYGKDTAATQLVVPFFKEVMPQLGLAYILLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPLASELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEEEEECCCCCHHHHHH
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVE
HHHHHHHHCCCCEEHEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR
HHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA