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The map label for this gene is ftsW [H]

Identifier: 59712809

GI number: 59712809

Start: 2473693

End: 2474823

Strand: Reverse

Name: ftsW [H]

Synonym: VF_2202

Alternate gene names: 59712809

Gene position: 2474823-2473693 (Counterclockwise)

Preceding gene: 59712810

Following gene: 59712808

Centisome position: 85.41

GC content: 38.9

Gene sequence:

>1131_bases
ATGTTCGATCGTCAGTTGATATGGATTTCTTTAGGTTTAATGCTTACTGGATTGATCATGGTAGGTTCTGCGTCGTTTCC
TATTAGTACACGCTTAACTGATCAGCCTTTTCACTTTATGCTTCGTCACATGTTGTTTGTGTGTTTGGCTCTTGGTGCCT
CATCTGTTGTATTGCGAATCCAATTAGATACTTGGTTAAAATACAGTGGCAAATTTTTATTTGTATCCATTTTATTATTA
ATTGCGGTGTTGCTGGTTGGTAAATCGGTAAATGGTGCTGCCCGTTGGCTACCTCTTGGTATCTTCAACTTGCAGCCAGC
CGAAGTTGCAAAACTTTCTCTATTTATTTTTATTTCGGGATACTTAGTTCGCCGCCATGGTGAAGTGAGAGAAAGTTTCA
AAGGGTTTGTTAAACCATTAATCGTACTTATCACTCTAGCATTTTTCTTATTATTGCAGCCCGATTTAGGTACCACGATC
GTAATGTTTGTCACTACTATCGGTATGCTATTTATTGCGGGTGCAAAGCTTTGGCAATTTATTGCTTTAGTGATGAGTGG
CATTTCATTAGTGATTGTTCTGATTATTGCAGAACCTTATCGTATGCGCCGTGTGACTTCTTTCTTAGATCCATGGCAAG
ACCCATTTGGTAGTGGTTACCAACTAACTCAATCTCTTATGGCATTTGGTCGTGGTAGTTGGTTTGGTGAAGGTTTAGGT
AATTCGATTCAAAAGCTAGAGTACCTACCTGAGGCTCATACTGACTTTGTATTTGCTGTGGTTGCTGAAGAATTAGGTTT
TGTTGGTGTCACTCTGATTTTGGTTTTAATTTTCGCTTTAGTATTAAAAGCATTACTTATTGGGCGAAAATGTCTTCAAC
ATGATCAACGCTTTGGTGGATTTTTAGCTTTTGGTATTGGGATTTGGTTTGCATTTCAAACCTTGGTCAATGTTGGTGCC
GCAGCAGGTATTGTTCCGACAAAAGGCTTAACACTACCACTCATCAGTTATGGTGGTTCCAGTTTGATTATCATGTCAGT
TGCCGTATCGTTACTCATCCGTATTGATCATGAATGTCGTCTCTATTTAGAAAATGAGCCTCCTCGGAGTGAAAATGAAG
AACAAAAATAA

Upstream 100 bases:

>100_bases
CAAAACAGTATTCAATTGAGAGTTAATTTTGGCATTTGAGCGAATTAAACAAGGGATCTTTTCCATTCAAGATTGGTGTT
TAACACCGTCACCTAAAGTC

Downstream 100 bases:

>100_bases
ACGTTTATTAGTGATGGCTGGTGGTACTGGCGGTCACGTTTTCCCAGGCCTTGCTGTTGCAAAGCAATTACAAAGTGAAG
GATGGGAGATCCGTTGGTTG

Product: integral membrane protein involved in stabilizing FtsZ ring during cell division

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MFDRQLIWISLGLMLTGLIMVGSASFPISTRLTDQPFHFMLRHMLFVCLALGASSVVLRIQLDTWLKYSGKFLFVSILLL
IAVLLVGKSVNGAARWLPLGIFNLQPAEVAKLSLFIFISGYLVRRHGEVRESFKGFVKPLIVLITLAFFLLLQPDLGTTI
VMFVTTIGMLFIAGAKLWQFIALVMSGISLVIVLIIAEPYRMRRVTSFLDPWQDPFGSGYQLTQSLMAFGRGSWFGEGLG
NSIQKLEYLPEAHTDFVFAVVAEELGFVGVTLILVLIFALVLKALLIGRKCLQHDQRFGGFLAFGIGIWFAFQTLVNVGA
AAGIVPTKGLTLPLISYGGSSLIIMSVAVSLLIRIDHECRLYLENEPPRSENEEQK

Sequences:

>Translated_376_residues
MFDRQLIWISLGLMLTGLIMVGSASFPISTRLTDQPFHFMLRHMLFVCLALGASSVVLRIQLDTWLKYSGKFLFVSILLL
IAVLLVGKSVNGAARWLPLGIFNLQPAEVAKLSLFIFISGYLVRRHGEVRESFKGFVKPLIVLITLAFFLLLQPDLGTTI
VMFVTTIGMLFIAGAKLWQFIALVMSGISLVIVLIIAEPYRMRRVTSFLDPWQDPFGSGYQLTQSLMAFGRGSWFGEGLG
NSIQKLEYLPEAHTDFVFAVVAEELGFVGVTLILVLIFALVLKALLIGRKCLQHDQRFGGFLAFGIGIWFAFQTLVNVGA
AAGIVPTKGLTLPLISYGGSSLIIMSVAVSLLIRIDHECRLYLENEPPRSENEEQK
>Mature_376_residues
MFDRQLIWISLGLMLTGLIMVGSASFPISTRLTDQPFHFMLRHMLFVCLALGASSVVLRIQLDTWLKYSGKFLFVSILLL
IAVLLVGKSVNGAARWLPLGIFNLQPAEVAKLSLFIFISGYLVRRHGEVRESFKGFVKPLIVLITLAFFLLLQPDLGTTI
VMFVTTIGMLFIAGAKLWQFIALVMSGISLVIVLIIAEPYRMRRVTSFLDPWQDPFGSGYQLTQSLMAFGRGSWFGEGLG
NSIQKLEYLPEAHTDFVFAVVAEELGFVGVTLILVLIFALVLKALLIGRKCLQHDQRFGGFLAFGIGIWFAFQTLVNVGA
AAGIVPTKGLTLPLISYGGSSLIIMSVAVSLLIRIDHECRLYLENEPPRSENEEQK

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=361, Percent_Identity=61.4958448753463, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1786853, Length=338, Percent_Identity=32.5443786982249, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41680; Mature: 41680

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRQLIWISLGLMLTGLIMVGSASFPISTRLTDQPFHFMLRHMLFVCLALGASSVVLRI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
QLDTWLKYSGKFLFVSILLLIAVLLVGKSVNGAARWLPLGIFNLQPAEVAKLSLFIFISG
EEHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHH
YLVRRHGEVRESFKGFVKPLIVLITLAFFLLLQPDLGTTIVMFVTTIGMLFIAGAKLWQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IALVMSGISLVIVLIIAEPYRMRRVTSFLDPWQDPFGSGYQLTQSLMAFGRGSWFGEGLG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCC
NSIQKLEYLPEAHTDFVFAVVAEELGFVGVTLILVLIFALVLKALLIGRKCLQHDQRFGG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
FLAFGIGIWFAFQTLVNVGAAAGIVPTKGLTLPLISYGGSSLIIMSVAVSLLIRIDHECR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHCCCCCE
LYLENEPPRSENEEQK
EEECCCCCCCCCCCCC
>Mature Secondary Structure
MFDRQLIWISLGLMLTGLIMVGSASFPISTRLTDQPFHFMLRHMLFVCLALGASSVVLRI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
QLDTWLKYSGKFLFVSILLLIAVLLVGKSVNGAARWLPLGIFNLQPAEVAKLSLFIFISG
EEHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHH
YLVRRHGEVRESFKGFVKPLIVLITLAFFLLLQPDLGTTIVMFVTTIGMLFIAGAKLWQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IALVMSGISLVIVLIIAEPYRMRRVTSFLDPWQDPFGSGYQLTQSLMAFGRGSWFGEGLG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCC
NSIQKLEYLPEAHTDFVFAVVAEELGFVGVTLILVLIFALVLKALLIGRKCLQHDQRFGG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
FLAFGIGIWFAFQTLVNVGAAAGIVPTKGLTLPLISYGGSSLIIMSVAVSLLIRIDHECR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHCCCCCE
LYLENEPPRSENEEQK
EEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]