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The map label for this gene is murG [H]

Identifier: 59712808

GI number: 59712808

Start: 2472645

End: 2473709

Strand: Reverse

Name: murG [H]

Synonym: VF_2201

Alternate gene names: 59712808

Gene position: 2473709-2472645 (Counterclockwise)

Preceding gene: 59712809

Following gene: 59712807

Centisome position: 85.37

GC content: 41.5

Gene sequence:

>1065_bases
ATGAAGAACAAAAATAAACGTTTATTAGTGATGGCTGGTGGTACTGGCGGTCACGTTTTCCCAGGCCTTGCTGTTGCAAA
GCAATTACAAAGTGAAGGATGGGAGATCCGTTGGTTGGGAACCGCTGACCGAATGGAAGCAGATTTAGTTCCTAAGCATG
GTATTGAAATTGATTTTATTAAAGTCAAAGGTCTTCGTGGGCAGGGACTTAAAAAGTTAATAGCTGCACCATTTCAAATC
TTAGGCGCAATATCTCAAGCGAAAAAACACATTAAAGCATGGCAACCAGATGTGGTACTAGGAATGGGGGGCTATGTAAG
TGGTCCTGGTGGTATCGCTGCTTGGTTATCAGGTATTCCTGTTGTATTGCATGAACAAAATGCGGTTGCTGGTTTAACTA
ATCAATGGTTATCTAAAATAGCAAAACGTGTGTTCCAAGCATTTCCTGGCGCTTTCCCTAATGCTGAAGTTGTAGGGAAT
CCGGTTCGTGAGGATGTATGTCAATTACCTCATCCAAAAGAAAGATTTGCACAGAGAACTGGCCCTATCCGTTTATTAGT
GATGGGAGGTAGTCAAGGTGCTCGTATTTTAAATACGACATTACCAGAAGCATTACCTCAATTAAGTCATGAGATTGAAA
TCTGGCATCAAGCAGGTAAAGGCTCACAAGAAACGGTAGAACAAGCGTATCGTGATAACGGTATTGCTGATGCGAAAGTA
ACTGAGTTTATCGATAATGTTGCAGAAGCTTATGCGTGGGCTGATTTATTGGTTTGTCGTTCTGGTGCATTAACGGTTTC
GGAAGTATCTGCAGCTGGTGTTGGTTCTATATTTATTCCATTTATGCATAAAGATCGCCAGCAAGCATTGAATGCTGATC
ACTTAGTACAATGTGGCGCAGCGCAAATGATTGAACAACAAGATTTAACAGTTCAGGGATTGGTTGATACACTGAACGGT
TTAGAGCGAAAACAATTACTCGAAATGGCATGTAATGCTCGAGACGCAGCAATTATCGATGCTGATGTGCGTGTTGCTAA
TGCAATAAAAAGCCTCGCTAAATAA

Upstream 100 bases:

>100_bases
GGTTCCAGTTTGATTATCATGTCAGTTGCCGTATCGTTACTCATCCGTATTGATCATGAATGTCGTCTCTATTTAGAAAA
TGAGCCTCCTCGGAGTGAAA

Downstream 100 bases:

>100_bases
GAATTGAGATTAAGAATGACAAAAGAACAGAAACTGCAATTAGCTGAAATAAGAACCATGATCCCTGAAATGCGTCGTGT
GGAGTGCATTCACTTCGTTG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGLKKLIAAPFQI
LGAISQAKKHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNAEVVGN
PVREDVCQLPHPKERFAQRTGPIRLLVMGGSQGARILNTTLPEALPQLSHEIEIWHQAGKGSQETVEQAYRDNGIADAKV
TEFIDNVAEAYAWADLLVCRSGALTVSEVSAAGVGSIFIPFMHKDRQQALNADHLVQCGAAQMIEQQDLTVQGLVDTLNG
LERKQLLEMACNARDAAIIDADVRVANAIKSLAK

Sequences:

>Translated_354_residues
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGLKKLIAAPFQI
LGAISQAKKHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNAEVVGN
PVREDVCQLPHPKERFAQRTGPIRLLVMGGSQGARILNTTLPEALPQLSHEIEIWHQAGKGSQETVEQAYRDNGIADAKV
TEFIDNVAEAYAWADLLVCRSGALTVSEVSAAGVGSIFIPFMHKDRQQALNADHLVQCGAAQMIEQQDLTVQGLVDTLNG
LERKQLLEMACNARDAAIIDADVRVANAIKSLAK
>Mature_354_residues
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGLKKLIAAPFQI
LGAISQAKKHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNAEVVGN
PVREDVCQLPHPKERFAQRTGPIRLLVMGGSQGARILNTTLPEALPQLSHEIEIWHQAGKGSQETVEQAYRDNGIADAKV
TEFIDNVAEAYAWADLLVCRSGALTVSEVSAAGVGSIFIPFMHKDRQQALNADHLVQCGAAQMIEQQDLTVQGLVDTLNG
LERKQLLEMACNARDAAIIDADVRVANAIKSLAK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=354, Percent_Identity=65.2542372881356, Blast_Score=482, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38174; Mature: 38174

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTADRMEADLVPKHGIEIDFI
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCEEEEE
KVKGLRGQGLKKLIAAPFQILGAISQAKKHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHCCCC
VVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNAEVVGNPVREDVCQLPHPKERFAQRT
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHCCCCCHHHHHHCC
GPIRLLVMGGSQGARILNTTLPEALPQLSHEIEIWHQAGKGSQETVEQAYRDNGIADAKV
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHH
TEFIDNVAEAYAWADLLVCRSGALTVSEVSAAGVGSIFIPFMHKDRQQALNADHLVQCGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEHHHHHCCHHHHCCHHHHHHHCH
AQMIEQQDLTVQGLVDTLNGLERKQLLEMACNARDAAIIDADVRVANAIKSLAK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTADRMEADLVPKHGIEIDFI
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCEEEEE
KVKGLRGQGLKKLIAAPFQILGAISQAKKHIKAWQPDVVLGMGGYVSGPGGIAAWLSGIP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHCCCC
VVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNAEVVGNPVREDVCQLPHPKERFAQRT
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHCCCCCHHHHHHCC
GPIRLLVMGGSQGARILNTTLPEALPQLSHEIEIWHQAGKGSQETVEQAYRDNGIADAKV
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHH
TEFIDNVAEAYAWADLLVCRSGALTVSEVSAAGVGSIFIPFMHKDRQQALNADHLVQCGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEHHHHHCCHHHHCCHHHHHHHCH
AQMIEQQDLTVQGLVDTLNGLERKQLLEMACNARDAAIIDADVRVANAIKSLAK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA