Click here to switch to the map view.

The map label for this gene is glxK [H]

Identifier: 59712764

GI number: 59712764

Start: 2414345

End: 2415475

Strand: Direct

Name: glxK [H]

Synonym: VF_2157

Alternate gene names: 59712764

Gene position: 2414345-2415475 (Clockwise)

Preceding gene: 59712763

Following gene: 59712768

Centisome position: 83.32

GC content: 42.0

Gene sequence:

>1131_bases
ATGAAAATCGTTATTGCTCCTGACTCTTACAAAGAAAGTTTAACGGCGATGGAAGTCGCTACGGCCATTGAAGCTGGATT
TAAACAAGTATTACCTCATGCTGAATATATAAAGTTACCTATGGCCGATGGTGGTGAAGGTACGGTTCAATCACTGATTG
ATGCAACTGGTGGCTCAATTATCGAGCACACAGTAACAGCGCCTCTTGGTGAACAAATTACCGGTTTTTATGGATTATTT
GGCGATGGTCAAACAGCCATTATCGAGATGGCAGCTGCATCAGGTTTACACCTTGTTGAACCAAGTTTACGTAACCCTCT
AAATACCACCACTTATGGTACTGGCGAACTAATTAAAGCGGCGCTTGATAAAGGTGTAAAACACATAATTGTAGGAATCG
GTGGCAGCGCTACAAATGATGGCGGGATCGGTATGGCTCAAGCTCTTGGCATTAAGTTGCTGGATCAAGATGGTAACGAT
CTTGCCTTTGGTGGTGGTTCATTAGCACAGCTTGCAACGATCGATACATTAAATAAAGATCCTCGTCTTGATGATATTAA
ACTTGAAGTTGCATGCGATGTTGATAACCCACTGTGTGGACCTAAAGGTGCTTCTTTCGTGTTTGGCCCACAAAAAGGGG
CAACTCCTGAGATGGTTAGCACGTTAGATAACAACCTAAGCCATTATGCCGATATAATGAAAGATCAACTTGGTAAAGAC
GTAAAAGACACAGCTGGAGCTGGCGCTGCAGGTGGGCTTGGTGCCGCCTTACTTGGTTTATTTAGTGCAACTCTGCGTCC
TGGTATTGAAATCGTAATGGATGCCGTAAATCTATCAGATGTTGTATCAAGTGCCGATCTTGTTATCACAGGAGAAGGTC
GAATCGATAGCCAAACTATTCATGGAAAAACACCGATTGGCGTAGCAAGAACAGCGAAAAAATTTGATTTACCTGTTATT
GGTATTGCAGGTTGTTTATCTGATGATTGTGCAATTGTTCATGAGTATGGTATTGATGCGGTATTTAGTGTTGTCCCTCG
CTCAGTTTCTCTTGAGCTTGCATTAAAAGAAGCAGCTATTAACGTAGAAAATACCGCTCGTAATGTTGCAACAATATATT
CAATGAAATAG

Upstream 100 bases:

>100_bases
AAAACTTATTCCATACGAATCAGCGGTTGGTCTAATGATCGCAACTGTTTCAACCCTCATCTTTGGCGTCTTCGGTTTAT
TTGTTTAATAAGGCTATATT

Downstream 100 bases:

>100_bases
GTAAGTATCCAGCCCTCTAAATAAAAAAGCAGCCAATTGGCTGCTTTTTGTATTTATGAAGATAAGGTTAAGCTGGCTCT
TGGAAAATAACCGTATCCGC

Product: glycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKIVIAPDSYKESLTAMEVATAIEAGFKQVLPHAEYIKLPMADGGEGTVQSLIDATGGSIIEHTVTAPLGEQITGFYGLF
GDGQTAIIEMAAASGLHLVEPSLRNPLNTTTYGTGELIKAALDKGVKHIIVGIGGSATNDGGIGMAQALGIKLLDQDGND
LAFGGGSLAQLATIDTLNKDPRLDDIKLEVACDVDNPLCGPKGASFVFGPQKGATPEMVSTLDNNLSHYADIMKDQLGKD
VKDTAGAGAAGGLGAALLGLFSATLRPGIEIVMDAVNLSDVVSSADLVITGEGRIDSQTIHGKTPIGVARTAKKFDLPVI
GIAGCLSDDCAIVHEYGIDAVFSVVPRSVSLELALKEAAINVENTARNVATIYSMK

Sequences:

>Translated_376_residues
MKIVIAPDSYKESLTAMEVATAIEAGFKQVLPHAEYIKLPMADGGEGTVQSLIDATGGSIIEHTVTAPLGEQITGFYGLF
GDGQTAIIEMAAASGLHLVEPSLRNPLNTTTYGTGELIKAALDKGVKHIIVGIGGSATNDGGIGMAQALGIKLLDQDGND
LAFGGGSLAQLATIDTLNKDPRLDDIKLEVACDVDNPLCGPKGASFVFGPQKGATPEMVSTLDNNLSHYADIMKDQLGKD
VKDTAGAGAAGGLGAALLGLFSATLRPGIEIVMDAVNLSDVVSSADLVITGEGRIDSQTIHGKTPIGVARTAKKFDLPVI
GIAGCLSDDCAIVHEYGIDAVFSVVPRSVSLELALKEAAINVENTARNVATIYSMK
>Mature_376_residues
MKIVIAPDSYKESLTAMEVATAIEAGFKQVLPHAEYIKLPMADGGEGTVQSLIDATGGSIIEHTVTAPLGEQITGFYGLF
GDGQTAIIEMAAASGLHLVEPSLRNPLNTTTYGTGELIKAALDKGVKHIIVGIGGSATNDGGIGMAQALGIKLLDQDGND
LAFGGGSLAQLATIDTLNKDPRLDDIKLEVACDVDNPLCGPKGASFVFGPQKGATPEMVSTLDNNLSHYADIMKDQLGKD
VKDTAGAGAAGGLGAALLGLFSATLRPGIEIVMDAVNLSDVVSSADLVITGEGRIDSQTIHGKTPIGVARTAKKFDLPVI
GIAGCLSDDCAIVHEYGIDAVFSVVPRSVSLELALKEAAINVENTARNVATIYSMK

Specific function: Glyoxylate catabolism. [C]

COG id: COG1929

COG function: function code G; Glycerate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerate kinase type-1 family [H]

Homologues:

Organism=Escherichia coli, GI1786724, Length=371, Percent_Identity=58.4905660377358, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI145693185, Length=375, Percent_Identity=58.9333333333333, Blast_Score=406, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018193
- InterPro:   IPR004381 [H]

Pfam domain/function: PF02595 Gly_kinase [H]

EC number: =2.7.1.31 [H]

Molecular weight: Translated: 38772; Mature: 38772

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIAPDSYKESLTAMEVATAIEAGFKQVLPHAEYIKLPMADGGEGTVQSLIDATGGSI
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCH
IEHTVTAPLGEQITGFYGLFGDGQTAIIEMAAASGLHLVEPSLRNPLNTTTYGTGELIKA
HHHHHCCCCCHHHHHHEEECCCCCEEEEEEHHHCCCEEECHHHCCCCCCCCCCHHHHHHH
ALDKGVKHIIVGIGGSATNDGGIGMAQALGIKLLDQDGNDLAFGGGSLAQLATIDTLNKD
HHHCCCEEEEEECCCCCCCCCCCCHHHHHCEEEECCCCCEEEECCCCHHHHHHHHHCCCC
PRLDDIKLEVACDVDNPLCGPKGASFVFGPQKGATPEMVSTLDNNLSHYADIMKDQLGKD
CCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VKDTAGAGAAGGLGAALLGLFSATLRPGIEIVMDAVNLSDVVSSADLVITGEGRIDSQTI
HHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHCCCCEEEECCCCCCCCEE
HGKTPIGVARTAKKFDLPVIGIAGCLSDDCAIVHEYGIDAVFSVVPRSVSLELALKEAAI
CCCCCCCHHHHHHHCCCCEEEEHHHCCCCCHHHHHHCHHHHHHHCCCCEEEEEEEHHHHC
NVENTARNVATIYSMK
CHHHHHCCEEEEEECC
>Mature Secondary Structure
MKIVIAPDSYKESLTAMEVATAIEAGFKQVLPHAEYIKLPMADGGEGTVQSLIDATGGSI
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCH
IEHTVTAPLGEQITGFYGLFGDGQTAIIEMAAASGLHLVEPSLRNPLNTTTYGTGELIKA
HHHHHCCCCCHHHHHHEEECCCCCEEEEEEHHHCCCEEECHHHCCCCCCCCCCHHHHHHH
ALDKGVKHIIVGIGGSATNDGGIGMAQALGIKLLDQDGNDLAFGGGSLAQLATIDTLNKD
HHHCCCEEEEEECCCCCCCCCCCCHHHHHCEEEECCCCCEEEECCCCHHHHHHHHHCCCC
PRLDDIKLEVACDVDNPLCGPKGASFVFGPQKGATPEMVSTLDNNLSHYADIMKDQLGKD
CCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VKDTAGAGAAGGLGAALLGLFSATLRPGIEIVMDAVNLSDVVSSADLVITGEGRIDSQTI
HHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHCCCCEEEECCCCCCCCEE
HGKTPIGVARTAKKFDLPVIGIAGCLSDDCAIVHEYGIDAVFSVVPRSVSLELALKEAAI
CCCCCCCHHHHHHHCCCCEEEEHHHCCCCCHHHHHHCHHHHHHHCCCCEEEEEEEHHHHC
NVENTARNVATIYSMK
CHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 3020045 [H]