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The map label for this gene is mcp4 [H]

Identifier: 59712768

GI number: 59712768

Start: 2427059

End: 2428555

Strand: Direct

Name: mcp4 [H]

Synonym: VF_2161

Alternate gene names: 59712768

Gene position: 2427059-2428555 (Clockwise)

Preceding gene: 59712764

Following gene: 59712771

Centisome position: 83.76

GC content: 37.21

Gene sequence:

>1497_bases
ATGAAGCTAAAAAACCAATCTTACGTTCTGGCTACCATCATTTTTTGTTCTCTTATATTAATGACAGCAACAGGTTTATG
GACTTTACGAGTTGCAAGTACAATAGACAACAAATCTCGAGTAACTGAGATTTTTCAAACTACCTATAACTTAATTACCA
ATATGGAGAATATGGTAGAAGAAGGAAAGATTGAAGAATCAAAAGCGAAAGAACTTACTATTACTATATTACGTAATAAC
ATCTATAAAGATAATGAATACGTTTATGTTGCTGATGAAAACTTAACTTTTCTTGCTGCACCTTTAGATCCTCAGCTACA
CGACACAAGTTTTCATGAATTTAGAGATAGTGAAGGCCGTAGCGTAGGACAAATTTTAGAAAATGCCATTAATCAAAACC
CAAATGGTATGGCTGAATATACTTGGTCCTTAAAAATGCCAGATGGCAGTATTGATAAAAAACTATCTATTGCTGAAAAA
ACACATAAATGGAATTGGATTGTCGGCACAGGTATTGGCGAAACAGAAGTAAATGAACGCTTTTGGGCAACAGCACAATG
GCAATTCGGGTTAGCTTTTATCATTGCTAGCTTAATACTTAGCATTTTAATGATTGCAATTAAACGTATGCTTGCCCTGC
TTGGTGGCGAACCTCACGATGTACGATCTGCAATTCAAACAGTTGCAGCAGGACAAATCGTCACTCAATTTGATACTAAA
GCCCCTGAAGGCAGTATTTATCAAGCAGTTCAAACAATGAACCTTTCTTTAGCTGAACTTGTTGAGCATTTAACCCAATC
AATGATTGCATTGAAAGACGAGTTATCTGATGTGCATTCTCGTTCAGGTACAGTAAGTCAACTGACTGAAGATCAGCACC
AATCAACAGAAATGATTGCTACAGCTATAACTGAAATGGCATCTTCTGCAAACAACGTAGCAGAATCAGCACAGCAAACA
GCTATCAATACAGATAATGCAGACAAACAAAGTGTACGTACACAAGAGTTAATTAATGCTACCGTATCAAACATTGAAGG
TTTAGCCGAGCAATTAAGTACTGCAAGTACAGCCGTAGCTGAGCTAGATAATGAAGTAAATAGTATTGTTAAAGTGTTAG
ATGTAATTGGTGATATTGCTGAACAAACAAACTTATTAGCATTAAACGCAGCAATTGAAGCAGCACGAGCTGGTGAGCAA
GGACGTGGGTTTGCTGTTGTTGCAGATGAAGTTCGTAACCTTGCAGGCCGAACTCAAGGCAGCACTAAAGAAATTCAACA
AATGATTTCTAACCTTCAAGAAGGTTCACATAATGCTATTTCTACTATGGAAGTATGTGCAGAAACGAGTAAGAGCACAG
TATCTGAGTCAAAAAATGCCTCTGATGCTTTACAACAAATTGTAACGGCTCTTGAAACGATCTCTAGCATGAGCCACCAG
ATAGCAAGTGCATCAGAAGAACAAAATACGTTAGCGAAGATATTACACAACGAGTAA

Upstream 100 bases:

>100_bases
TATAAAGCGCCAAAATTCCACTCTAAAGTGGTATTTATTAAACTTATAAATCATTCTGCCGATACATATACATCAGACTA
ATAATCAAGGATCACAAGGC

Downstream 100 bases:

>100_bases
ATATCATTGAGGAAAGTGGTCAACAACTAGCGAAAGTGTCGCTGATAGTCAAAACAGCACTCAAACATTAACAGAGCTTG
CCGATGACCTTGAGACTTGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MKLKNQSYVLATIIFCSLILMTATGLWTLRVASTIDNKSRVTEIFQTTYNLITNMENMVEEGKIEESKAKELTITILRNN
IYKDNEYVYVADENLTFLAAPLDPQLHDTSFHEFRDSEGRSVGQILENAINQNPNGMAEYTWSLKMPDGSIDKKLSIAEK
THKWNWIVGTGIGETEVNERFWATAQWQFGLAFIIASLILSILMIAIKRMLALLGGEPHDVRSAIQTVAAGQIVTQFDTK
APEGSIYQAVQTMNLSLAELVEHLTQSMIALKDELSDVHSRSGTVSQLTEDQHQSTEMIATAITEMASSANNVAESAQQT
AINTDNADKQSVRTQELINATVSNIEGLAEQLSTASTAVAELDNEVNSIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQGSTKEIQQMISNLQEGSHNAISTMEVCAETSKSTVSESKNASDALQQIVTALETISSMSHQ
IASASEEQNTLAKILHNE

Sequences:

>Translated_498_residues
MKLKNQSYVLATIIFCSLILMTATGLWTLRVASTIDNKSRVTEIFQTTYNLITNMENMVEEGKIEESKAKELTITILRNN
IYKDNEYVYVADENLTFLAAPLDPQLHDTSFHEFRDSEGRSVGQILENAINQNPNGMAEYTWSLKMPDGSIDKKLSIAEK
THKWNWIVGTGIGETEVNERFWATAQWQFGLAFIIASLILSILMIAIKRMLALLGGEPHDVRSAIQTVAAGQIVTQFDTK
APEGSIYQAVQTMNLSLAELVEHLTQSMIALKDELSDVHSRSGTVSQLTEDQHQSTEMIATAITEMASSANNVAESAQQT
AINTDNADKQSVRTQELINATVSNIEGLAEQLSTASTAVAELDNEVNSIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQGSTKEIQQMISNLQEGSHNAISTMEVCAETSKSTVSESKNASDALQQIVTALETISSMSHQ
IASASEEQNTLAKILHNE
>Mature_498_residues
MKLKNQSYVLATIIFCSLILMTATGLWTLRVASTIDNKSRVTEIFQTTYNLITNMENMVEEGKIEESKAKELTITILRNN
IYKDNEYVYVADENLTFLAAPLDPQLHDTSFHEFRDSEGRSVGQILENAINQNPNGMAEYTWSLKMPDGSIDKKLSIAEK
THKWNWIVGTGIGETEVNERFWATAQWQFGLAFIIASLILSILMIAIKRMLALLGGEPHDVRSAIQTVAAGQIVTQFDTK
APEGSIYQAVQTMNLSLAELVEHLTQSMIALKDELSDVHSRSGTVSQLTEDQHQSTEMIATAITEMASSANNVAESAQQT
AINTDNADKQSVRTQELINATVSNIEGLAEQLSTASTAVAELDNEVNSIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRNLAGRTQGSTKEIQQMISNLQEGSHNAISTMEVCAETSKSTVSESKNASDALQQIVTALETISSMSHQ
IASASEEQNTLAKILHNE

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=312, Percent_Identity=30.4487179487179, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI2367378, Length=315, Percent_Identity=29.5238095238095, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787690, Length=313, Percent_Identity=31.9488817891374, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1788194, Length=306, Percent_Identity=29.4117647058824, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789453, Length=201, Percent_Identity=34.3283582089552, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54398; Mature: 54398

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKNQSYVLATIIFCSLILMTATGLWTLRVASTIDNKSRVTEIFQTTYNLITNMENMVE
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EGKIEESKAKELTITILRNNIYKDNEYVYVADENLTFLAAPLDPQLHDTSFHEFRDSEGR
HCCCCHHHHHHEEEEEEECCCCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHCCCCC
SVGQILENAINQNPNGMAEYTWSLKMPDGSIDKKLSIAEKTHKWNWIVGTGIGETEVNER
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHCHH
FWATAQWQFGLAFIIASLILSILMIAIKRMLALLGGEPHDVRSAIQTVAAGQIVTQFDTK
HEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
APEGSIYQAVQTMNLSLAELVEHLTQSMIALKDELSDVHSRSGTVSQLTEDQHQSTEMIA
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TAITEMASSANNVAESAQQTAINTDNADKQSVRTQELINATVSNIEGLAEQLSTASTAVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELDNEVNSIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQG
HHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCC
STKEIQQMISNLQEGSHNAISTMEVCAETSKSTVSESKNASDALQQIVTALETISSMSHQ
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IASASEEQNTLAKILHNE
HHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKLKNQSYVLATIIFCSLILMTATGLWTLRVASTIDNKSRVTEIFQTTYNLITNMENMVE
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EGKIEESKAKELTITILRNNIYKDNEYVYVADENLTFLAAPLDPQLHDTSFHEFRDSEGR
HCCCCHHHHHHEEEEEEECCCCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHCCCCC
SVGQILENAINQNPNGMAEYTWSLKMPDGSIDKKLSIAEKTHKWNWIVGTGIGETEVNER
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHCHH
FWATAQWQFGLAFIIASLILSILMIAIKRMLALLGGEPHDVRSAIQTVAAGQIVTQFDTK
HEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
APEGSIYQAVQTMNLSLAELVEHLTQSMIALKDELSDVHSRSGTVSQLTEDQHQSTEMIA
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TAITEMASSANNVAESAQQTAINTDNADKQSVRTQELINATVSNIEGLAEQLSTASTAVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELDNEVNSIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQG
HHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCC
STKEIQQMISNLQEGSHNAISTMEVCAETSKSTVSESKNASDALQQIVTALETISSMSHQ
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IASASEEQNTLAKILHNE
HHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]