Click here to switch to the map view.

The map label for this gene is cadC [H]

Identifier: 59712667

GI number: 59712667

Start: 2295157

End: 2296782

Strand: Reverse

Name: cadC [H]

Synonym: VF_2060

Alternate gene names: 59712667

Gene position: 2296782-2295157 (Counterclockwise)

Preceding gene: 59712668

Following gene: 59712665

Centisome position: 79.27

GC content: 36.9

Gene sequence:

>1626_bases
ATGGTCGGGATCTGTTTTCAAATTAATGACTGGACTCTAGTTATTGAGGAAAATAAGTTATATCGCCAAGATAGGGAAGT
GTCGGTTGAACCACGTTTAATTAATTTACTTCGCTTTTTAGCACAGCATTCAGGTGAAGTATTTTGTCGAGATGAGTTAA
TTAAACATGTATGGGATGGTGCGTTTGTTACCGATCAAGTGGTAACACAATCAATATTTGAACTGCGAAAAGTATTGCGT
GATGGTCGTTTAGATAACACTCGTTATTTAGTTACGGTACCAAAACGTGGGTATAAGTTGGTTGCAGAAACCAAGCAAAT
AAGATTAGAAGATACGCCTTATTGGAAACCTTGCGATACATTTACCTCAACAGAAGCTGATGAAAATCAGAATCATAATG
TTGAATTGAACACCGAAGAGCAAGAAAAAGAACAAGATGAGACTGCACAACTCTCTTTTCCAGCAGGTCCATTAACTCGT
GCTGTAACTAATATTTCTAATCAAGTATCAAACGAAAAGAAAAAGCAGGGTGAGAGTTTTAGCTTTTTACATCGTTGGAA
GCTATTAGCGTTCGACTTTTTTCTCGTTGGCGTATTAATTGCGGTTATTTTTTCAGTTACTTATCAGCAAACAACCACTC
ATATAACCAAGGCTGTTGATACTGATTTAATTGAATTTACCTATCACGCAAGCCGTAACTCGAATAATGAAACAGAATAT
TTGGCTGATGGCATTAGTCAAAAACTGATGGCAGATTTAGCCAGTGTTGGCCATTACCGAGTTCAGTTAAATAAAACCGC
ATTTACTACCGGTATTTTGCCTGGAAAAGCGGTGAATGTACGAGTAGAAGAACAACAAAATAAAACGTATTTAGATGTAG
AGTATCGCAGTAATATTTCAAATCGAGTGCTGTTTAGTCGTCAATATTTAATGACCAATGCCAATTTAGAACATGTGTTG
CGCCAATCATCTCAAGATTTAATGCGAGCGTTAGGGGTTCAGGCATCCGAACAAGATATGAATAGATTAATGCTTGGTTT
ACCAAAGGAGCATGGTTTATTAGAGATGTTAGTTCGAGCTAATCACTTCATTAATCAAACGGATCAAAAAAACTTTGAAA
AAGGGATAGATCTGTTAGAGAACATTGCATTAGCAGAGCCGAATAATGATTATGTGCTTTCAGAGTTATACATTGCTTAT
AACGCATATTCAGCGCTTAACCCTGAATTAGAGTTGGACGAAAACACCGCTAAAATTGAAAAGTTAAGTCAGGATCTTCA
AGCTAGATATGCTTTATCGGATGTCGGTGTATTGCCTTCTCGTATCTATGAAGCATTAGCTATGATAGCGATTAAGCAAG
ATAACAAAGAAGATGCTAGAGCTTATCTTAACCTAGCATTTAAGAATAGAGAGTCAGCATTCTCTTATATATTAGAAGGG
AAACTTGCTGAGTTAGATGGCGACTTAGATCAAGCAGGGGAGTCATACAGCAAGGCTTTCTTTATGGATACGTCACTTGA
AACTTATATGCTTGCTGAAAATCTTGCATTTTACAGTGATTTAGAAACCGTTGCTTATTTTATGTATCGAGCCGTTAATC
CAAGTGAAGTTCGCTTGATGGGGTAA

Upstream 100 bases:

>100_bases
CAACTTCTTCAAAAGGAGAGCTTGAAAATAAGATAAACCTTATTATTTTTGAGGCCTTTCTTCTTTTATATTTATATCAA
TTCATACAAATGAGTATCTT

Downstream 100 bases:

>100_bases
TCGTGATTAACGATTCATGCAGTATATTGGTGTAATAAAAAAGCCCGTCGAATTTAGTTCGACGGGCTTTTTTTAACTAA
TTGTGGATTAAATTAGTGTT

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MVGICFQINDWTLVIEENKLYRQDREVSVEPRLINLLRFLAQHSGEVFCRDELIKHVWDGAFVTDQVVTQSIFELRKVLR
DGRLDNTRYLVTVPKRGYKLVAETKQIRLEDTPYWKPCDTFTSTEADENQNHNVELNTEEQEKEQDETAQLSFPAGPLTR
AVTNISNQVSNEKKKQGESFSFLHRWKLLAFDFFLVGVLIAVIFSVTYQQTTTHITKAVDTDLIEFTYHASRNSNNETEY
LADGISQKLMADLASVGHYRVQLNKTAFTTGILPGKAVNVRVEEQQNKTYLDVEYRSNISNRVLFSRQYLMTNANLEHVL
RQSSQDLMRALGVQASEQDMNRLMLGLPKEHGLLEMLVRANHFINQTDQKNFEKGIDLLENIALAEPNNDYVLSELYIAY
NAYSALNPELELDENTAKIEKLSQDLQARYALSDVGVLPSRIYEALAMIAIKQDNKEDARAYLNLAFKNRESAFSYILEG
KLAELDGDLDQAGESYSKAFFMDTSLETYMLAENLAFYSDLETVAYFMYRAVNPSEVRLMG

Sequences:

>Translated_541_residues
MVGICFQINDWTLVIEENKLYRQDREVSVEPRLINLLRFLAQHSGEVFCRDELIKHVWDGAFVTDQVVTQSIFELRKVLR
DGRLDNTRYLVTVPKRGYKLVAETKQIRLEDTPYWKPCDTFTSTEADENQNHNVELNTEEQEKEQDETAQLSFPAGPLTR
AVTNISNQVSNEKKKQGESFSFLHRWKLLAFDFFLVGVLIAVIFSVTYQQTTTHITKAVDTDLIEFTYHASRNSNNETEY
LADGISQKLMADLASVGHYRVQLNKTAFTTGILPGKAVNVRVEEQQNKTYLDVEYRSNISNRVLFSRQYLMTNANLEHVL
RQSSQDLMRALGVQASEQDMNRLMLGLPKEHGLLEMLVRANHFINQTDQKNFEKGIDLLENIALAEPNNDYVLSELYIAY
NAYSALNPELELDENTAKIEKLSQDLQARYALSDVGVLPSRIYEALAMIAIKQDNKEDARAYLNLAFKNRESAFSYILEG
KLAELDGDLDQAGESYSKAFFMDTSLETYMLAENLAFYSDLETVAYFMYRAVNPSEVRLMG
>Mature_541_residues
MVGICFQINDWTLVIEENKLYRQDREVSVEPRLINLLRFLAQHSGEVFCRDELIKHVWDGAFVTDQVVTQSIFELRKVLR
DGRLDNTRYLVTVPKRGYKLVAETKQIRLEDTPYWKPCDTFTSTEADENQNHNVELNTEEQEKEQDETAQLSFPAGPLTR
AVTNISNQVSNEKKKQGESFSFLHRWKLLAFDFFLVGVLIAVIFSVTYQQTTTHITKAVDTDLIEFTYHASRNSNNETEY
LADGISQKLMADLASVGHYRVQLNKTAFTTGILPGKAVNVRVEEQQNKTYLDVEYRSNISNRVLFSRQYLMTNANLEHVL
RQSSQDLMRALGVQASEQDMNRLMLGLPKEHGLLEMLVRANHFINQTDQKNFEKGIDLLENIALAEPNNDYVLSELYIAY
NAYSALNPELELDENTAKIEKLSQDLQARYALSDVGVLPSRIYEALAMIAIKQDNKEDARAYLNLAFKNRESAFSYILEG
KLAELDGDLDQAGESYSKAFFMDTSLETYMLAENLAFYSDLETVAYFMYRAVNPSEVRLMG

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=149, Percent_Identity=39.5973154362416, Blast_Score=111, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 62029; Mature: 62029

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGICFQINDWTLVIEENKLYRQDREVSVEPRLINLLRFLAQHSGEVFCRDELIKHVWDG
CEEEEEEECCEEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCC
AFVTDQVVTQSIFELRKVLRDGRLDNTRYLVTVPKRGYKLVAETKQIRLEDTPYWKPCDT
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECHHEEEECCCCCCCCCCC
FTSTEADENQNHNVELNTEEQEKEQDETAQLSFPAGPLTRAVTNISNQVSNEKKKQGESF
CCCCCCCCCCCCCEEECCCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCH
SFLHRWKLLAFDFFLVGVLIAVIFSVTYQQTTTHITKAVDTDLIEFTYHASRNSNNETEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEECCCCCCCCHHH
LADGISQKLMADLASVGHYRVQLNKTAFTTGILPGKAVNVRVEEQQNKTYLDVEYRSNIS
HHHHHHHHHHHHHHHCCCEEEEEECEEEEECCCCCCEEEEEEECCCCCEEEEEEHHCCCC
NRVLFSRQYLMTNANLEHVLRQSSQDLMRALGVQASEQDMNRLMLGLPKEHGLLEMLVRA
HHEEEEHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
NHFINQTDQKNFEKGIDLLENIALAEPNNDYVLSELYIAYNAYSALNPELELDENTAKIE
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCEECCCHHHHH
KLSQDLQARYALSDVGVLPSRIYEALAMIAIKQDNKEDARAYLNLAFKNRESAFSYILEG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCC
KLAELDGDLDQAGESYSKAFFMDTSLETYMLAENLAFYSDLETVAYFMYRAVNPSEVRLM
HHHHCCCCHHHCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
G
C
>Mature Secondary Structure
MVGICFQINDWTLVIEENKLYRQDREVSVEPRLINLLRFLAQHSGEVFCRDELIKHVWDG
CEEEEEEECCEEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCC
AFVTDQVVTQSIFELRKVLRDGRLDNTRYLVTVPKRGYKLVAETKQIRLEDTPYWKPCDT
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECHHEEEECCCCCCCCCCC
FTSTEADENQNHNVELNTEEQEKEQDETAQLSFPAGPLTRAVTNISNQVSNEKKKQGESF
CCCCCCCCCCCCCEEECCCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCH
SFLHRWKLLAFDFFLVGVLIAVIFSVTYQQTTTHITKAVDTDLIEFTYHASRNSNNETEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEECCCCCCCCHHH
LADGISQKLMADLASVGHYRVQLNKTAFTTGILPGKAVNVRVEEQQNKTYLDVEYRSNIS
HHHHHHHHHHHHHHHCCCEEEEEECEEEEECCCCCCEEEEEEECCCCCEEEEEEHHCCCC
NRVLFSRQYLMTNANLEHVLRQSSQDLMRALGVQASEQDMNRLMLGLPKEHGLLEMLVRA
HHEEEEHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
NHFINQTDQKNFEKGIDLLENIALAEPNNDYVLSELYIAYNAYSALNPELELDENTAKIE
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCEECCCHHHHH
KLSQDLQARYALSDVGVLPSRIYEALAMIAIKQDNKEDARAYLNLAFKNRESAFSYILEG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCC
KLAELDGDLDQAGESYSKAFFMDTSLETYMLAENLAFYSDLETVAYFMYRAVNPSEVRLM
HHHHCCCCHHHCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]