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The map label for this gene is btuR [H]

Identifier: 59712357

GI number: 59712357

Start: 1975022

End: 1975627

Strand: Direct

Name: btuR [H]

Synonym: VF_1750

Alternate gene names: 59712357

Gene position: 1975022-1975627 (Clockwise)

Preceding gene: 59712356

Following gene: 59712361

Centisome position: 68.16

GC content: 37.46

Gene sequence:

>606_bases
ATGACTGAACAAGATAAAAAAGTCGAACGTTACAAACAACGTCAAGAAAAAATTAAAAACAACGTTGATAAACGTGTGGC
CGAGGCTCAAGAAGAAAAAGGTCTACTCTTAATCATTACAGGAAATGGTAAAGGAAAAACCACATCAGGCTTTGGTACTG
TCGCTAGAGCAGTTGGTCATGGACTTAATTGCATAGTAGCTCAATTTATCAAAGGCACTTGGGATTGCGGTGAACGAAAT
TTATTAGAAATGCATAACGTGCCATTCTATGTAATGAAAACTGGCTTTACTTGGAATACTCAAGATAAAGAATCAGATAC
AAAAGCAGCTCAAGCCGTATGGGAAGAATGTAAAAAAGCGCTCGAAGATGAGTCTATCGATTTAGTTTTGCTTGATGAAA
TGACGTATATGGTCACCTATGGCTATATTGATTTGAAAGAAGTAAAAACAGCACTATCGAATCGTCCTAAAATGCAATCT
GTCGTTATTACAGGACGAGCAGCACATCGTGAGTTAATTGAAATGGCGGATACCGTTTCTGAAGTGCGAAGTGTTAAACA
TGCATTCGATTCTGGTATTAAAGCGTTAAAAGGCATTGATTGGTAA

Upstream 100 bases:

>100_bases
ATAGGCACATAGCTCAAATTCATTGATAGACTTTAAAAATCCCGATATGGTTCTCCTGTCGGGATTTTTTATATTCACCT
TTCTTTTAATGGAATAAAAC

Downstream 100 bases:

>100_bases
TGTCTAAAACAAAAATGGCCTACAATCTTAATGATGCAGGCCATTTCTTTATATGATGCTATAGATCAAACTTAGTTAAA
AAGTCCTTTAAGTAATTTAT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTEQDKKVERYKQRQEKIKNNVDKRVAEAQEEKGLLLIITGNGKGKTTSGFGTVARAVGHGLNCIVAQFIKGTWDCGERN
LLEMHNVPFYVMKTGFTWNTQDKESDTKAAQAVWEECKKALEDESIDLVLLDEMTYMVTYGYIDLKEVKTALSNRPKMQS
VVITGRAAHRELIEMADTVSEVRSVKHAFDSGIKALKGIDW

Sequences:

>Translated_201_residues
MTEQDKKVERYKQRQEKIKNNVDKRVAEAQEEKGLLLIITGNGKGKTTSGFGTVARAVGHGLNCIVAQFIKGTWDCGERN
LLEMHNVPFYVMKTGFTWNTQDKESDTKAAQAVWEECKKALEDESIDLVLLDEMTYMVTYGYIDLKEVKTALSNRPKMQS
VVITGRAAHRELIEMADTVSEVRSVKHAFDSGIKALKGIDW
>Mature_200_residues
TEQDKKVERYKQRQEKIKNNVDKRVAEAQEEKGLLLIITGNGKGKTTSGFGTVARAVGHGLNCIVAQFIKGTWDCGERNL
LEMHNVPFYVMKTGFTWNTQDKESDTKAAQAVWEECKKALEDESIDLVLLDEMTYMVTYGYIDLKEVKTALSNRPKMQSV
VITGRAAHRELIEMADTVSEVRSVKHAFDSGIKALKGIDW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=193, Percent_Identity=61.6580310880829, Blast_Score=264, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22675; Mature: 22544

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQDKKVERYKQRQEKIKNNVDKRVAEAQEEKGLLLIITGNGKGKTTSGFGTVARAVGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHC
GLNCIVAQFIKGTWDCGERNLLEMHNVPFYVMKTGFTWNTQDKESDTKAAQAVWEECKKA
CHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHH
LEDESIDLVLLDEMTYMVTYGYIDLKEVKTALSNRPKMQSVVITGRAAHRELIEMADTVS
HCCCCCCEEEECHHHHHHHCCCCCHHHHHHHHCCCCCHHHEEEECHHHHHHHHHHHHHHH
EVRSVKHAFDSGIKALKGIDW
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEQDKKVERYKQRQEKIKNNVDKRVAEAQEEKGLLLIITGNGKGKTTSGFGTVARAVGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHC
GLNCIVAQFIKGTWDCGERNLLEMHNVPFYVMKTGFTWNTQDKESDTKAAQAVWEECKKA
CHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHH
LEDESIDLVLLDEMTYMVTYGYIDLKEVKTALSNRPKMQSVVITGRAAHRELIEMADTVS
HCCCCCCEEEECHHHHHHHCCCCCHHHHHHHHCCCCCHHHEEEECHHHHHHHHHHHHHHH
EVRSVKHAFDSGIKALKGIDW
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916712; 11677609; 7860601; 2403541 [H]