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The map label for this gene is hns [H]

Identifier: 59712238

GI number: 59712238

Start: 1834206

End: 1834727

Strand: Direct

Name: hns [H]

Synonym: VF_1631

Alternate gene names: 59712238

Gene position: 1834206-1834727 (Clockwise)

Preceding gene: 59712231

Following gene: 59712241

Centisome position: 63.3

GC content: 34.67

Gene sequence:

>522_bases
ATGGATATTATTAATATTAATATCATTAATATTTTTTTATTCCTTTATCTAGAAATTTGTTATATTATTTTTCTGTTATA
TTATAATCATATTATCAAAATAATTATGGAATCAAATATGTCTGATACAATTAAAACGCTGCTTAACCTACGCAGCCTAC
GTGCTTTATCTCGCGAAATGACTTTAGAACAATTAGAAGAAGCATTAGAAAAACTTCAATCTGTTGTTGCAGAACGTCAA
GAATCTGAAGCAGAAGAGCGCGCTCAACTAGCTGAAAAACAAGCTAAACTTGAAGAGTTCCGTCAAATGATGATCGACAG
CGGCATCGCTCCTGAAGATCTATTAGACACTATGTCTGCTACAACAGTAAAAACAAAACAAAAACGCGCACCTCGTCCTG
CAAAATATAAATTCCAAGATCACGCTGGTGAAGAGAAAACATGGACAGGCCAAGGCCGTACTCCTTCAGCTCTTCAAGCA
CAGCTTGATGCTGGTAAAAAACTAGAAGAGTTTTTAATCTAA

Upstream 100 bases:

>100_bases
CAATTTTGCAATACTATATCTGAGTATTTTAACATTAAGTTATCTAGCTAATTAGAATGAAACATTTTAAAGCTATTTAG
TAGCAGTCTTATCCTTAAGA

Downstream 100 bases:

>100_bases
TAATACTCTTTAAAGAGCATATAAAAAGACCACTTACTCTAAGTGGTCTTTTTTTATTTTCATTTTATTACATTTAGAAA
CGTATTATTGCTCGAAACTT

Product: global DNA-binding transcriptional dual regulator H-NS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MDIININIINIFLFLYLEICYIIFLLYYNHIIKIIMESNMSDTIKTLLNLRSLRALSREMTLEQLEEALEKLQSVVAERQ
ESEAEERAQLAEKQAKLEEFRQMMIDSGIAPEDLLDTMSATTVKTKQKRAPRPAKYKFQDHAGEEKTWTGQGRTPSALQA
QLDAGKKLEEFLI

Sequences:

>Translated_173_residues
MDIININIINIFLFLYLEICYIIFLLYYNHIIKIIMESNMSDTIKTLLNLRSLRALSREMTLEQLEEALEKLQSVVAERQ
ESEAEERAQLAEKQAKLEEFRQMMIDSGIAPEDLLDTMSATTVKTKQKRAPRPAKYKFQDHAGEEKTWTGQGRTPSALQA
QLDAGKKLEEFLI
>Mature_173_residues
MDIININIINIFLFLYLEICYIIFLLYYNHIIKIIMESNMSDTIKTLLNLRSLRALSREMTLEQLEEALEKLQSVVAERQ
ESEAEERAQLAEKQAKLEEFRQMMIDSGIAPEDLLDTMSATTVKTKQKRAPRPAKYKFQDHAGEEKTWTGQGRTPSALQA
QLDAGKKLEEFLI

Specific function: Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription [H]

COG id: COG2916

COG function: function code R; DNA-binding protein H-NS

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone-like protein H-NS family [H]

Homologues:

Organism=Escherichia coli, GI1787489, Length=135, Percent_Identity=51.8518518518518, Blast_Score=123, Evalue=6e-30,
Organism=Escherichia coli, GI1789023, Length=134, Percent_Identity=48.5074626865672, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: 820 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1780 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1020 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 4632 Molecules/Cell In: Gr

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001801 [H]

Pfam domain/function: PF00816 Histone_HNS [H]

EC number: NA

Molecular weight: Translated: 19998; Mature: 19998

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIININIINIFLFLYLEICYIIFLLYYNHIIKIIMESNMSDTIKTLLNLRSLRALSREM
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TLEQLEEALEKLQSVVAERQESEAEERAQLAEKQAKLEEFRQMMIDSGIAPEDLLDTMSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TTVKTKQKRAPRPAKYKFQDHAGEEKTWTGQGRTPSALQAQLDAGKKLEEFLI
HHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure
MDIININIINIFLFLYLEICYIIFLLYYNHIIKIIMESNMSDTIKTLLNLRSLRALSREM
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TLEQLEEALEKLQSVVAERQESEAEERAQLAEKQAKLEEFRQMMIDSGIAPEDLLDTMSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TTVKTKQKRAPRPAKYKFQDHAGEEKTWTGQGRTPSALQAQLDAGKKLEEFLI
HHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]