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The map label for this gene is yocR [H]

Identifier: 59712212

GI number: 59712212

Start: 1800318

End: 1801742

Strand: Reverse

Name: yocR [H]

Synonym: VF_1605

Alternate gene names: 59712212

Gene position: 1801742-1800318 (Counterclockwise)

Preceding gene: 59712214

Following gene: 59712207

Centisome position: 62.18

GC content: 39.44

Gene sequence:

>1425_bases
ATGAGCGCTTCTACGAAGCCCCGCGACAATTGGGGTTCAAAGTTAGGGTTTGTCATGGCGGCAGCGGGATCAGCTGTTGG
CCTTGGTAATATTTGGAAGTTTCCATATACAGCTGGAGATAATGGTGGTGGTGCATTTGTTGTTATCTATCTGTTCTTCG
TTATTTTTATCGGTTTTAGTGTGATGTTGACTGAGTTTGCTATCGGTCGTCGAACACAAAAATCAGCAGTAGGTGCTTTT
AAATCTACAGATCGCCGTTGGACCTTTGCTGGTGTCATCGGTGTAACAAGTGGTCTATTGATCATGGGTTTCTACCCTGT
AGTAGGTGGTTGGGCTATTGCTTACATTGCTAAAGTTGGTACGGGCTTATTAAGCGCTCCAGAAGCAATTGGTGATAGTT
TTGGTGGATTTATTTCTGATCCAATTCAACCGTTAATGTGGATGGCTTTTTATCTATTTTTAAATATCGTCATTGTAATG
AAAGGTATTTCTGGTGGTATTGAGAAAGCAGGTAAAATATTAATGCCATTGCTTTTCATTATCCTGATTATTGTTTCAGT
AAAAGGGTTAATGCTTCCTGGTTCAATGGCGGGTCTTGAGTTTTTATTTAGTCCTGATTTTTCAAAAATTGATAGTAACG
TTATTTTGGCTGCTCTAGGCCAAGCTTTCTTTTCATTATCTTTGGGTATGGGTTGTATGATGACGTACGGTTCTTATTTG
AAGAAAAAAGAAAACTTAGTACAAACAACAGCAATGGTTACAGCAATGGATACAGGCGTTGCAATTCTTGCTGGTGTAGC
AATGTTCCCTGCAATGTTTGCATTTGGTATGGCACCAACAGCAGGGCCGGGTCTTGTATTTGTTGTGGTACCTCAGTTAT
TTGCTGAAATGGGCGGAATTATCGGTCTTCTTTTAGCTCTTATGTTCTTTATTGGTTTAAGTGTTGCTGCACTGACATCT
TCTGTTTCTTTATTAGAAGTTGTTGTGTCTTACTTAATTGATGAAAAAGGGTTATCACGTGTTAAAGCGGTGATTACAGC
AAGTTCGGTAATGGCTGTTTTATGTATCTTTGCTTCTCTATCTTTAGGTGGCGTTGGACCAACATTATTTGATACTGGTG
CCTTTGATATTTTTGACTTGTTAACAGATAAAATCTTCTTAGCCGTTGGCGGTATGTTGGTATGTATCTTTGCTGGTTGG
AGATTGAAACGTGAAGATCTAGAAGATGAGATCACGAACGGTGGTGAAGTGAAATTCCCATTGTTTGGTCTATGGTATGC
TTTAGTTAAGTTTATCATCCCTGTGGCAATCGCAATTGTTGCATTTATGGGGATTTCATCAGGATTTGATAGTGGCAAAG
GCGCTATTATGCTGCTTGGTGTAGGTATTATTGCAGGTGCTGCACTGATATCGAAAAAATTCTAA

Upstream 100 bases:

>100_bases
GTACGCCATTCCAATTTTTAGAATGTACAAAAATATGTACACAACATTTTTGGCGTAAATTTATTAACACAGCATGGATA
GTTTGGAGATAAACGTGGGT

Downstream 100 bases:

>100_bases
TTTAAGAATTAGTATTGAAAATAAAAAACGAGAGCAAGCGCTCTCGTTTTTTTTATGTCTTTTACTCTACATCACCATCA
ATATAGAACCACTTACCATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSASTKPRDNWGSKLGFVMAAAGSAVGLGNIWKFPYTAGDNGGGAFVVIYLFFVIFIGFSVMLTEFAIGRRTQKSAVGAF
KSTDRRWTFAGVIGVTSGLLIMGFYPVVGGWAIAYIAKVGTGLLSAPEAIGDSFGGFISDPIQPLMWMAFYLFLNIVIVM
KGISGGIEKAGKILMPLLFIILIIVSVKGLMLPGSMAGLEFLFSPDFSKIDSNVILAALGQAFFSLSLGMGCMMTYGSYL
KKKENLVQTTAMVTAMDTGVAILAGVAMFPAMFAFGMAPTAGPGLVFVVVPQLFAEMGGIIGLLLALMFFIGLSVAALTS
SVSLLEVVVSYLIDEKGLSRVKAVITASSVMAVLCIFASLSLGGVGPTLFDTGAFDIFDLLTDKIFLAVGGMLVCIFAGW
RLKREDLEDEITNGGEVKFPLFGLWYALVKFIIPVAIAIVAFMGISSGFDSGKGAIMLLGVGIIAGAALISKKF

Sequences:

>Translated_474_residues
MSASTKPRDNWGSKLGFVMAAAGSAVGLGNIWKFPYTAGDNGGGAFVVIYLFFVIFIGFSVMLTEFAIGRRTQKSAVGAF
KSTDRRWTFAGVIGVTSGLLIMGFYPVVGGWAIAYIAKVGTGLLSAPEAIGDSFGGFISDPIQPLMWMAFYLFLNIVIVM
KGISGGIEKAGKILMPLLFIILIIVSVKGLMLPGSMAGLEFLFSPDFSKIDSNVILAALGQAFFSLSLGMGCMMTYGSYL
KKKENLVQTTAMVTAMDTGVAILAGVAMFPAMFAFGMAPTAGPGLVFVVVPQLFAEMGGIIGLLLALMFFIGLSVAALTS
SVSLLEVVVSYLIDEKGLSRVKAVITASSVMAVLCIFASLSLGGVGPTLFDTGAFDIFDLLTDKIFLAVGGMLVCIFAGW
RLKREDLEDEITNGGEVKFPLFGLWYALVKFIIPVAIAIVAFMGISSGFDSGKGAIMLLGVGIIAGAALISKKF
>Mature_473_residues
SASTKPRDNWGSKLGFVMAAAGSAVGLGNIWKFPYTAGDNGGGAFVVIYLFFVIFIGFSVMLTEFAIGRRTQKSAVGAFK
STDRRWTFAGVIGVTSGLLIMGFYPVVGGWAIAYIAKVGTGLLSAPEAIGDSFGGFISDPIQPLMWMAFYLFLNIVIVMK
GISGGIEKAGKILMPLLFIILIIVSVKGLMLPGSMAGLEFLFSPDFSKIDSNVILAALGQAFFSLSLGMGCMMTYGSYLK
KKENLVQTTAMVTAMDTGVAILAGVAMFPAMFAFGMAPTAGPGLVFVVVPQLFAEMGGIIGLLLALMFFIGLSVAALTSS
VSLLEVVVSYLIDEKGLSRVKAVITASSVMAVLCIFASLSLGGVGPTLFDTGAFDIFDLLTDKIFLAVGGMLVCIFAGWR
LKREDLEDEITNGGEVKFPLFGLWYALVKFIIPVAIAIVAFMGISSGFDSGKGAIMLLGVGIIAGAALISKKF

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=422, Percent_Identity=26.5402843601896, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI21361581, Length=431, Percent_Identity=27.1461716937355, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI7657587, Length=472, Percent_Identity=26.9067796610169, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4507041, Length=415, Percent_Identity=26.5060240963855, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI58219014, Length=300, Percent_Identity=31.3333333333333, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI4507043, Length=404, Percent_Identity=25.990099009901, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI194018524, Length=293, Percent_Identity=29.0102389078498, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI171184408, Length=380, Percent_Identity=26.3157894736842, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI171184406, Length=380, Percent_Identity=26.3157894736842, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI171184404, Length=380, Percent_Identity=26.3157894736842, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI289191351, Length=432, Percent_Identity=25.6944444444444, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4557046, Length=432, Percent_Identity=25.6944444444444, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI197276623, Length=346, Percent_Identity=27.7456647398844, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI54607094, Length=346, Percent_Identity=27.7456647398844, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI289191377, Length=432, Percent_Identity=25.6944444444444, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI134304856, Length=342, Percent_Identity=28.6549707602339, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI11181770, Length=293, Percent_Identity=28.6689419795222, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI33354281, Length=301, Percent_Identity=25.2491694352159, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI51468073, Length=298, Percent_Identity=24.8322147651007, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI67782317, Length=395, Percent_Identity=25.3164556962025, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI67782313, Length=396, Percent_Identity=25.5050505050505, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI67782315, Length=396, Percent_Identity=25.5050505050505, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI300360519, Length=396, Percent_Identity=25.2525252525253, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI12408638, Length=269, Percent_Identity=25.6505576208178, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI5032097, Length=352, Percent_Identity=23.5795454545455, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI92859670, Length=272, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI218563756, Length=343, Percent_Identity=23.9067055393586, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI21361693, Length=117, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI197276625, Length=117, Percent_Identity=35.8974358974359, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI289191353, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554804, Length=464, Percent_Identity=26.0775862068966, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI25146584, Length=393, Percent_Identity=25.1908396946565, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17569475, Length=412, Percent_Identity=24.0291262135922, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI133952791, Length=250, Percent_Identity=28, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI212642127, Length=306, Percent_Identity=28.4313725490196, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17542050, Length=147, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71998244, Length=286, Percent_Identity=27.6223776223776, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555248, Length=225, Percent_Identity=27.1111111111111, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995588, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535731, Length=121, Percent_Identity=33.0578512396694, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24762620, Length=417, Percent_Identity=27.3381294964029, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17136952, Length=384, Percent_Identity=27.34375, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281364394, Length=384, Percent_Identity=27.34375, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI28574704, Length=384, Percent_Identity=27.34375, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI17136950, Length=384, Percent_Identity=27.34375, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI28574702, Length=384, Percent_Identity=27.34375, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24639514, Length=501, Percent_Identity=24.9500998003992, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI221329674, Length=430, Percent_Identity=26.5116279069767, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24639516, Length=295, Percent_Identity=30.5084745762712, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI19921936, Length=392, Percent_Identity=26.0204081632653, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45551088, Length=417, Percent_Identity=25.4196642685851, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24652942, Length=417, Percent_Identity=25.4196642685851, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24655079, Length=299, Percent_Identity=29.0969899665552, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281365034, Length=388, Percent_Identity=25.5154639175258, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24639853, Length=417, Percent_Identity=24.9400479616307, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24582567, Length=374, Percent_Identity=25.4010695187166, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24654186, Length=319, Percent_Identity=27.5862068965517, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45550877, Length=246, Percent_Identity=29.2682926829268, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45551183, Length=246, Percent_Identity=28.0487804878049, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281364136, Length=420, Percent_Identity=24.5238095238095, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24661428, Length=81, Percent_Identity=41.9753086419753, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19921352, Length=186, Percent_Identity=27.9569892473118, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584353, Length=186, Percent_Identity=27.9569892473118, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281363702, Length=207, Percent_Identity=26.5700483091787, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363700, Length=78, Percent_Identity=43.5897435897436, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49874; Mature: 49743

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SASTKPRDNWGSKLGFVMAAAGSAVGLGNIWKFPYTAGDNGGGAFVVIYLFFVIFIGFS
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]