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The map label for this gene is cysS [H]

Identifier: 59712207

GI number: 59712207

Start: 1795712

End: 1797097

Strand: Reverse

Name: cysS [H]

Synonym: VF_1600

Alternate gene names: 59712207

Gene position: 1797097-1795712 (Counterclockwise)

Preceding gene: 59712212

Following gene: 59712206

Centisome position: 62.02

GC content: 39.9

Gene sequence:

>1386_bases
ATGTTGAAAATATATAACTCACTTACACGTCAAAAAGAAGAATTTAAGCCAATTACCGAAGGTAAAGTCGGTATGTATGT
GTGTGGGGTTACCATTTACGATTTGTGTCATATCGGTCACGGTCGTACATTTGTCTCTTTTGATGTTATTTCTCGTTATT
TACGTTTTCTTGGTTACGATTTAACTTTTGTTCGTAACATCACAGATATTGATGACAAAATCATTAAACGTGCCGCTGAA
AATGGTGAAACATGTGATGCATTAACTGAGCGTTTGATTGCTGACATGCATGCTGATTTTGATGCGTTAAACATGAAACG
CCCAGATGTGGAACCTCGTGCAACAGAGTACATTAAAGAAATCATTGCATTGGTTGAGCGATTAATTGAGCGTGGCTTTG
CTTATGTGGCATCGAATGGCGATGTAATGTTCGAAGTGAAAAAATACGATGAATATGGTTGTCTTTCTCGTCAAGATCTT
GAACAACTTCAAGCTGGTTCCCGTGTTACATTAGAAGAAGCAAGTGTAAAACGTAGCGGAATGGATTTTGTTTTATGGAA
GATGTCAAAACCAGGTGAACCAACATGGGAATCTCCATGGGGACCAGGCCGTCCAGGTTGGCACATTGAGTGTTCAGCAA
TGAACTCATCTATTCTTGGTGATCATTTTGATATTCACGGTGGTGGTTCTGATTTGATGTTCCCACACCATGAAAATGAA
ATTGCTCAATCTTGCTGTGCACATGATACCCCATACGTAAATACTTGGATGCACAGTGGAATGGTGATGGTTGATCGTGA
GAAAATGTCTAAGTCATTAGGTAATTTCTTTACTATTCGTGACGTTCTTGCTCATTACGATTCAGAAACGGTTCGTTATT
TCTTAATGTCTGGTCACTACCGTAGCCAATTAAACTACAGTGAAGAGAATCTAAATCAAGCTCGTGCATCACTAGAGCGT
TTATACACATCGCTACGTGGTCTTGATCTATCAGTGACTCCTGCTGGTGGTGAAGAGTTTGTTGGTCGCTTCTCTACAGC
GATGAATGATGATTTTAATACACCAGAAGCGTATTCAGTATTATTTGAAATGGCTCGCGAAGTGAACCGTCTTAAAACTG
AAAATATAGATACTGCATCTAAATTAGGTGCATTAATGCGTGAACTAGCAGATGTATTAGGTTTATTATCACAAGAGCCT
GAAGCATTCTTACAAGGTGGAAGCAGCAATGATGATGTTGCGGAAATAGAAGCGTTAATTAAAGCGCGTAATGATGCTCG
TGCAGCAAAAGATTGGGCAGCAGCAGATGCTGCTCGTGATGCGATTGCTGCATTAAATATTGTATTAGAAGATGGCCCTG
AAGGAACAACGTGGCGTCGTAAGTAA

Upstream 100 bases:

>100_bases
ATTAATCAGAATCTACAGGGAATTTTCTTGCTATCAGCACTTAATATAGGTCTAATAGCTTATATATATCCTTTAAACAA
ATAATGAGTAAAAAAAGAGC

Downstream 100 bases:

>100_bases
TACAAACAGTTTTATATAAAGGGCTGGTATTTCCAGCCTTTTTTATTACCAAATTTTTAAACTTTAATAGAGGACACATT
TGTGGCACAAATGTATTTTT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MLKIYNSLTRQKEEFKPITEGKVGMYVCGVTIYDLCHIGHGRTFVSFDVISRYLRFLGYDLTFVRNITDIDDKIIKRAAE
NGETCDALTERLIADMHADFDALNMKRPDVEPRATEYIKEIIALVERLIERGFAYVASNGDVMFEVKKYDEYGCLSRQDL
EQLQAGSRVTLEEASVKRSGMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGDHFDIHGGGSDLMFPHHENE
IAQSCCAHDTPYVNTWMHSGMVMVDREKMSKSLGNFFTIRDVLAHYDSETVRYFLMSGHYRSQLNYSEENLNQARASLER
LYTSLRGLDLSVTPAGGEEFVGRFSTAMNDDFNTPEAYSVLFEMAREVNRLKTENIDTASKLGALMRELADVLGLLSQEP
EAFLQGGSSNDDVAEIEALIKARNDARAAKDWAAADAARDAIAALNIVLEDGPEGTTWRRK

Sequences:

>Translated_461_residues
MLKIYNSLTRQKEEFKPITEGKVGMYVCGVTIYDLCHIGHGRTFVSFDVISRYLRFLGYDLTFVRNITDIDDKIIKRAAE
NGETCDALTERLIADMHADFDALNMKRPDVEPRATEYIKEIIALVERLIERGFAYVASNGDVMFEVKKYDEYGCLSRQDL
EQLQAGSRVTLEEASVKRSGMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGDHFDIHGGGSDLMFPHHENE
IAQSCCAHDTPYVNTWMHSGMVMVDREKMSKSLGNFFTIRDVLAHYDSETVRYFLMSGHYRSQLNYSEENLNQARASLER
LYTSLRGLDLSVTPAGGEEFVGRFSTAMNDDFNTPEAYSVLFEMAREVNRLKTENIDTASKLGALMRELADVLGLLSQEP
EAFLQGGSSNDDVAEIEALIKARNDARAAKDWAAADAARDAIAALNIVLEDGPEGTTWRRK
>Mature_461_residues
MLKIYNSLTRQKEEFKPITEGKVGMYVCGVTIYDLCHIGHGRTFVSFDVISRYLRFLGYDLTFVRNITDIDDKIIKRAAE
NGETCDALTERLIADMHADFDALNMKRPDVEPRATEYIKEIIALVERLIERGFAYVASNGDVMFEVKKYDEYGCLSRQDL
EQLQAGSRVTLEEASVKRSGMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGDHFDIHGGGSDLMFPHHENE
IAQSCCAHDTPYVNTWMHSGMVMVDREKMSKSLGNFFTIRDVLAHYDSETVRYFLMSGHYRSQLNYSEENLNQARASLER
LYTSLRGLDLSVTPAGGEEFVGRFSTAMNDDFNTPEAYSVLFEMAREVNRLKTENIDTASKLGALMRELADVLGLLSQEP
EAFLQGGSSNDDVAEIEALIKARNDARAAKDWAAADAARDAIAALNIVLEDGPEGTTWRRK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=387, Percent_Identity=39.2764857881137, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI62240992, Length=233, Percent_Identity=43.3476394849785, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI10835051, Length=233, Percent_Identity=43.3476394849785, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI21269877, Length=233, Percent_Identity=43.3476394849785, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI303304987, Length=232, Percent_Identity=43.5344827586207, Blast_Score=197, Evalue=2e-50,
Organism=Escherichia coli, GI1786737, Length=463, Percent_Identity=74.7300215982721, Blast_Score=701, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509795, Length=250, Percent_Identity=40.8, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17509797, Length=250, Percent_Identity=40.8, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6324082, Length=330, Percent_Identity=35.1515151515151, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19922218, Length=501, Percent_Identity=33.9321357285429, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI19922364, Length=344, Percent_Identity=35.7558139534884, Blast_Score=196, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51932; Mature: 51932

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIYNSLTRQKEEFKPITEGKVGMYVCGVTIYDLCHIGHGRTFVSFDVISRYLRFLGYD
CCCHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCC
LTFVRNITDIDDKIIKRAAENGETCDALTERLIADMHADFDALNMKRPDVEPRATEYIKE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHH
IIALVERLIERGFAYVASNGDVMFEVKKYDEYGCLSRQDLEQLQAGSRVTLEEASVKRSG
HHHHHHHHHHCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHCC
MDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGDHFDIHGGGSDLMFPHHENE
CCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHH
IAQSCCAHDTPYVNTWMHSGMVMVDREKMSKSLGNFFTIRDVLAHYDSETVRYFLMSGHY
HHHHHHCCCCCCHHHHHHCCEEEEEHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCH
RSQLNYSEENLNQARASLERLYTSLRGLDLSVTPAGGEEFVGRFSTAMNDDFNTPEAYSV
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCCCHHHHH
LFEMAREVNRLKTENIDTASKLGALMRELADVLGLLSQEPEAFLQGGSSNDDVAEIEALI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHH
KARNDARAAKDWAAADAARDAIAALNIVLEDGPEGTTWRRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure
MLKIYNSLTRQKEEFKPITEGKVGMYVCGVTIYDLCHIGHGRTFVSFDVISRYLRFLGYD
CCCHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCC
LTFVRNITDIDDKIIKRAAENGETCDALTERLIADMHADFDALNMKRPDVEPRATEYIKE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHH
IIALVERLIERGFAYVASNGDVMFEVKKYDEYGCLSRQDLEQLQAGSRVTLEEASVKRSG
HHHHHHHHHHCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHCC
MDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGDHFDIHGGGSDLMFPHHENE
CCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHH
IAQSCCAHDTPYVNTWMHSGMVMVDREKMSKSLGNFFTIRDVLAHYDSETVRYFLMSGHY
HHHHHHCCCCCCHHHHHHCCEEEEEHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCH
RSQLNYSEENLNQARASLERLYTSLRGLDLSVTPAGGEEFVGRFSTAMNDDFNTPEAYSV
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCCCHHHHH
LFEMAREVNRLKTENIDTASKLGALMRELADVLGLLSQEPEAFLQGGSSNDDVAEIEALI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHH
KARNDARAAKDWAAADAARDAIAALNIVLEDGPEGTTWRRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA