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The map label for this gene is hutA [H]

Identifier: 59711841

GI number: 59711841

Start: 1369769

End: 1371967

Strand: Reverse

Name: hutA [H]

Synonym: VF_1234

Alternate gene names: 59711841

Gene position: 1371967-1369769 (Counterclockwise)

Preceding gene: 59711847

Following gene: 59711832

Centisome position: 47.35

GC content: 39.56

Gene sequence:

>2199_bases
ATGTCTAATAAAAAAACATTTTTAGCAGCGTCTATTCTCGTTGCACTATCTCCCACTCTCCAGGCTGAAACCTCATCAAA
TAAAGAAACAACCATGTTTGATGAAGTGGTTGTTTCTGCAACTCGTACAGAGCAAAGCATTAAAGACACATCCAGTTCAA
TTTCAAAAGTCACATCAGATGATATTGAAAAAACAATGGCAACCGACATTCAAGATGCTCTGAAATACACTCCAGGTGTT
TCGGCTAATGGCGGTGGCCGTTTTGGTCTATCAGGCTTTACCGTGCGCGGCATGAGTGACAGCCGTATAAAAATGTTAGT
TGATGGTGTTCAACAACCAACGCCTTATAACCCTGGTGCAAACGAACAACGTAAATACCCAAGCACTATTGAAATAGATA
CGCTAAAAGCAATTGAGGTAAATAAAGGGCCTTCTTCTACTCTATACGGCTCAGATGCACTTGGCGGAACAGTGCTAATG
GAAACGAAAAATCCTGAAGATATCTTAAGAACCGATGGCGACGAAAACGCATTTGAAGTAAAAACCAGCTATAACAGCAT
TGATACAAGCTCAAAGACAACGGGCACATGGGCAATGCGTGCGGCAGAGTTAGAAACACTTATCATGCTGACGTATAAAA
AAGGCAATGAATCACAAACTCATTCAAATGGTGCTGATATTGAAGGTCCTGATCGCGGTGCTGCTAACCCAGCCGATGCA
CAAATCGGTAACCTTCTTGCTAAAGCCTTTTACCAATTAAACGATTCACATCGTATCGGTGCTACTGTTGAATACTTCAC
CTCTCAATACGATGAAGATGAATTATCACAAAATGGTTATTCGATGATGAGTCGAGGCACCCCAATCATTACTTATTATG
ACAATTACAATAAAGATACAAACACTCGATTACGTGTTGGTTTAGAGCACGAATGGCAAGCGAATAATTTATTATTCGAT
ACGCTAGAATCAAAATTAAACGTACAACAAACTGAATCATTGTCAGAAAACTACGATACTTCAACAGGTCCTTATGGTAG
TGGTCGTCGTATGCGTGAACGTATTGCTACTGATGATTCTATCCAGTTTGACGCACAATTTGATAAAATTGCCGAGTTTG
GAGAAGGATTCCATCAAATCACTTATGGTGTAAGCTTTAGACAAAACAAGTTCGCAACTGAAAACACCGATTATAAATAC
GACAAAGGCACCGTTGGACCAGGTCATACCGATATGCCTGATGCAACAATGACTCAATACGGTATTTTTGCACAAGACCA
AGCTTTCTTATTCAATGAACAATTAGTGCTAACAGCAGGTTTACGCTATGACTCATTCAAAGCAGAACCTGAAACAAATG
AAGGCTTTAAAACAGAATATCCTGATAGCCAAAATGACGCTTTCACAGCTAAGTTAGGCTCGGTTTACCATATTAATAAT
AATTTCAGCGTACTTGGTCAAATTAGCCAAGGATTCAAAGCCCCGACTCTGCAAGATATGTACTACTTTTACGATAGTGG
CGCTGTCATCGATGCAAACCCAGATCTAAAAGCGGAAAGCAGTATTTCGTATGAAGCAGGTATTCGAGCTCAATCTAATG
CCGCACAACTTGAATTAATCGCTTTCTATAATGATTATTCTGATTTCATCAATCAACAATACTTAGGTAAAGTCGTTGGT
GGCCCGAACGATGGTAAAGAGCATTATACAAAAGAGAATATCGATTCAGCGGAAATTTATGGTATTGAATTTAGCTCAAC
GTATTTATTAGATGAAGCCTTCAATGCACCTCAAGGTACTTACTCTAAATTAAGCATTGCTTACGCAGAAGGCCGAGATA
AAAAGACAGGGGCTCCGATAGACAGTGTTGCTCCTCTTACTTCAAACCTAGGCTTAGGTTATGACTCTGTTGGTTACACT
TACGGTGCTTTATTAAACATTAATATGGTGGCAGGCAAAGATAAATGGTCAAACGTTGGTCATGAAAACATCAATGTTGC
AGGTTACACCTTGGTTGATCTAACCGCCTACTATAAACCAATGAAGGATTTAACACTTCGTGGTGGTTTATTTAATGCGT
TTGATAAGCAGTACTGGTTGTACAACGACATGATTGGTACTGAATCTGGCGATGATGGCATTGATCGTAAAGCTCAAGCA
GGTCGTAACTGGGGTATTGAGTTAGATTATAAATTCTAA

Upstream 100 bases:

>100_bases
AACAAAAAACGAAAAGATCAAATGAAAATGATAGTAATTATCATTCGTAATATGTATTATCTCCGGCAATTATGAGAGGA
CAACTTCAAAGGAAAAATTC

Downstream 100 bases:

>100_bases
AAAATAGCACTCAACGTTAATTGGCTAGTTCAAAGCGGCATCATCGCCGCTTTTTTTATGTTTGTTGTATTATGATTTTA
CTACTTCAGAGGGTTCAAAT

Product: heme transport protein HutA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MSNKKTFLAASILVALSPTLQAETSSNKETTMFDEVVVSATRTEQSIKDTSSSISKVTSDDIEKTMATDIQDALKYTPGV
SANGGGRFGLSGFTVRGMSDSRIKMLVDGVQQPTPYNPGANEQRKYPSTIEIDTLKAIEVNKGPSSTLYGSDALGGTVLM
ETKNPEDILRTDGDENAFEVKTSYNSIDTSSKTTGTWAMRAAELETLIMLTYKKGNESQTHSNGADIEGPDRGAANPADA
QIGNLLAKAFYQLNDSHRIGATVEYFTSQYDEDELSQNGYSMMSRGTPIITYYDNYNKDTNTRLRVGLEHEWQANNLLFD
TLESKLNVQQTESLSENYDTSTGPYGSGRRMRERIATDDSIQFDAQFDKIAEFGEGFHQITYGVSFRQNKFATENTDYKY
DKGTVGPGHTDMPDATMTQYGIFAQDQAFLFNEQLVLTAGLRYDSFKAEPETNEGFKTEYPDSQNDAFTAKLGSVYHINN
NFSVLGQISQGFKAPTLQDMYYFYDSGAVIDANPDLKAESSISYEAGIRAQSNAAQLELIAFYNDYSDFINQQYLGKVVG
GPNDGKEHYTKENIDSAEIYGIEFSSTYLLDEAFNAPQGTYSKLSIAYAEGRDKKTGAPIDSVAPLTSNLGLGYDSVGYT
YGALLNINMVAGKDKWSNVGHENINVAGYTLVDLTAYYKPMKDLTLRGGLFNAFDKQYWLYNDMIGTESGDDGIDRKAQA
GRNWGIELDYKF

Sequences:

>Translated_732_residues
MSNKKTFLAASILVALSPTLQAETSSNKETTMFDEVVVSATRTEQSIKDTSSSISKVTSDDIEKTMATDIQDALKYTPGV
SANGGGRFGLSGFTVRGMSDSRIKMLVDGVQQPTPYNPGANEQRKYPSTIEIDTLKAIEVNKGPSSTLYGSDALGGTVLM
ETKNPEDILRTDGDENAFEVKTSYNSIDTSSKTTGTWAMRAAELETLIMLTYKKGNESQTHSNGADIEGPDRGAANPADA
QIGNLLAKAFYQLNDSHRIGATVEYFTSQYDEDELSQNGYSMMSRGTPIITYYDNYNKDTNTRLRVGLEHEWQANNLLFD
TLESKLNVQQTESLSENYDTSTGPYGSGRRMRERIATDDSIQFDAQFDKIAEFGEGFHQITYGVSFRQNKFATENTDYKY
DKGTVGPGHTDMPDATMTQYGIFAQDQAFLFNEQLVLTAGLRYDSFKAEPETNEGFKTEYPDSQNDAFTAKLGSVYHINN
NFSVLGQISQGFKAPTLQDMYYFYDSGAVIDANPDLKAESSISYEAGIRAQSNAAQLELIAFYNDYSDFINQQYLGKVVG
GPNDGKEHYTKENIDSAEIYGIEFSSTYLLDEAFNAPQGTYSKLSIAYAEGRDKKTGAPIDSVAPLTSNLGLGYDSVGYT
YGALLNINMVAGKDKWSNVGHENINVAGYTLVDLTAYYKPMKDLTLRGGLFNAFDKQYWLYNDMIGTESGDDGIDRKAQA
GRNWGIELDYKF
>Mature_731_residues
SNKKTFLAASILVALSPTLQAETSSNKETTMFDEVVVSATRTEQSIKDTSSSISKVTSDDIEKTMATDIQDALKYTPGVS
ANGGGRFGLSGFTVRGMSDSRIKMLVDGVQQPTPYNPGANEQRKYPSTIEIDTLKAIEVNKGPSSTLYGSDALGGTVLME
TKNPEDILRTDGDENAFEVKTSYNSIDTSSKTTGTWAMRAAELETLIMLTYKKGNESQTHSNGADIEGPDRGAANPADAQ
IGNLLAKAFYQLNDSHRIGATVEYFTSQYDEDELSQNGYSMMSRGTPIITYYDNYNKDTNTRLRVGLEHEWQANNLLFDT
LESKLNVQQTESLSENYDTSTGPYGSGRRMRERIATDDSIQFDAQFDKIAEFGEGFHQITYGVSFRQNKFATENTDYKYD
KGTVGPGHTDMPDATMTQYGIFAQDQAFLFNEQLVLTAGLRYDSFKAEPETNEGFKTEYPDSQNDAFTAKLGSVYHINNN
FSVLGQISQGFKAPTLQDMYYFYDSGAVIDANPDLKAESSISYEAGIRAQSNAAQLELIAFYNDYSDFINQQYLGKVVGG
PNDGKEHYTKENIDSAEIYGIEFSSTYLLDEAFNAPQGTYSKLSIAYAEGRDKKTGAPIDSVAPLTSNLGLGYDSVGYTY
GALLNINMVAGKDKWSNVGHENINVAGYTLVDLTAYYKPMKDLTLRGGLFNAFDKQYWLYNDMIGTESGDDGIDRKAQAG
RNWGIELDYKF

Specific function: Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex and is required for heme uptake [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=697, Percent_Identity=24.103299856528, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788478, Length=128, Percent_Identity=37.5, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786798, Length=294, Percent_Identity=24.8299319727891, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80832; Mature: 80700

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKKTFLAASILVALSPTLQAETSSNKETTMFDEVVVSATRTEQSIKDTSSSISKVTSD
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIEKTMATDIQDALKYTPGVSANGGGRFGLSGFTVRGMSDSRIKMLVDGVQQPTPYNPGA
HHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCEEEECCCCCHHHHHHHCCCCCCCCCCCC
NEQRKYPSTIEIDTLKAIEVNKGPSSTLYGSDALGGTVLMETKNPEDILRTDGDENAFEV
CCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCEEEE
KTSYNSIDTSSKTTGTWAMRAAELETLIMLTYKKGNESQTHSNGADIEGPDRGAANPADA
EECCCCCCCCCCCCCHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHH
QIGNLLAKAFYQLNDSHRIGATVEYFTSQYDEDELSQNGYSMMSRGTPIITYYDNYNKDT
HHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHCCCHHHHHCCCCEEEEECCCCCCC
NTRLRVGLEHEWQANNLLFDTLESKLNVQQTESLSENYDTSTGPYGSGRRMRERIATDDS
CCEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCC
IQFDAQFDKIAEFGEGFHQITYGVSFRQNKFATENTDYKYDKGTVGPGHTDMPDATMTQY
EEECCHHHHHHHHCCCCEEEHCCEEECCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHH
GIFAQDQAFLFNEQLVLTAGLRYDSFKAEPETNEGFKTEYPDSQNDAFTAKLGSVYHINN
CEEECCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECC
NFSVLGQISQGFKAPTLQDMYYFYDSGAVIDANPDLKAESSISYEAGIRAQSNAAQLELI
CCEEEEEHHCCCCCCCHHHEEEEEECCEEEECCCCCCCCCCCCHHCCCCCCCCCCEEEEE
AFYNDYSDFINQQYLGKVVGGPNDGKEHYTKENIDSAEIYGIEFSSTYLLDEAFNAPQGT
EEECCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEECCEEEEHHHCCCCCCC
YSKLSIAYAEGRDKKTGAPIDSVAPLTSNLGLGYDSVGYTYGALLNINMVAGKDKWSNVG
CCEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEEEEEEECCCHHCCCC
HENINVAGYTLVDLTAYYKPMKDLTLRGGLFNAFDKQYWLYNDMIGTESGDDGIDRKAQA
CCCCEEEEEEEEEHHHHHCCHHHHEECCCHHHHHCCCEEEEECCCCCCCCCCCCCHHHHC
GRNWGIELDYKF
CCCCCEEEEECC
>Mature Secondary Structure 
SNKKTFLAASILVALSPTLQAETSSNKETTMFDEVVVSATRTEQSIKDTSSSISKVTSD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIEKTMATDIQDALKYTPGVSANGGGRFGLSGFTVRGMSDSRIKMLVDGVQQPTPYNPGA
HHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCEEEECCCCCHHHHHHHCCCCCCCCCCCC
NEQRKYPSTIEIDTLKAIEVNKGPSSTLYGSDALGGTVLMETKNPEDILRTDGDENAFEV
CCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCEEEE
KTSYNSIDTSSKTTGTWAMRAAELETLIMLTYKKGNESQTHSNGADIEGPDRGAANPADA
EECCCCCCCCCCCCCHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHH
QIGNLLAKAFYQLNDSHRIGATVEYFTSQYDEDELSQNGYSMMSRGTPIITYYDNYNKDT
HHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHCCCHHHHHCCCCEEEEECCCCCCC
NTRLRVGLEHEWQANNLLFDTLESKLNVQQTESLSENYDTSTGPYGSGRRMRERIATDDS
CCEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCC
IQFDAQFDKIAEFGEGFHQITYGVSFRQNKFATENTDYKYDKGTVGPGHTDMPDATMTQY
EEECCHHHHHHHHCCCCEEEHCCEEECCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHH
GIFAQDQAFLFNEQLVLTAGLRYDSFKAEPETNEGFKTEYPDSQNDAFTAKLGSVYHINN
CEEECCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECC
NFSVLGQISQGFKAPTLQDMYYFYDSGAVIDANPDLKAESSISYEAGIRAQSNAAQLELI
CCEEEEEHHCCCCCCCHHHEEEEEECCEEEECCCCCCCCCCCCHHCCCCCCCCCCEEEEE
AFYNDYSDFINQQYLGKVVGGPNDGKEHYTKENIDSAEIYGIEFSSTYLLDEAFNAPQGT
EEECCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEECCEEEEHHHCCCCCCC
YSKLSIAYAEGRDKKTGAPIDSVAPLTSNLGLGYDSVGYTYGALLNINMVAGKDKWSNVG
CCEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEEEEEEECCCHHCCCC
HENINVAGYTLVDLTAYYKPMKDLTLRGGLFNAFDKQYWLYNDMIGTESGDDGIDRKAQA
CCCCEEEEEEEEEHHHHHCCHHHHEECCCHHHHHCCCEEEEECCCCCCCCCCCCCHHHHC
GRNWGIELDYKF
CCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]