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The map label for this gene is asnC [H]

Identifier: 59711766

GI number: 59711766

Start: 1285182

End: 1286582

Strand: Reverse

Name: asnC [H]

Synonym: VF_1159

Alternate gene names: 59711766

Gene position: 1286582-1285182 (Counterclockwise)

Preceding gene: 59711773

Following gene: 59711762

Centisome position: 44.4

GC content: 44.75

Gene sequence:

>1401_bases
ATGACTTACGCGCCTGTAACAGACGTATTAAGCGGTAAACTAGCGGTTGACAGTGAAGTAACTGTTCGCGGTTGGATCCG
TTCGCGTCGCGATTCTAAAGCTGGTATTTCTTTCCTAGCTGTTTATGACGGTTCTTGTTTCGACCCGATTCAGGCCGTGG
TTCCTAATGACTTAAATAATTACAACGACGAAGTGCTTAAACTAACAACAGGTTGTTCTGTTGAAGTGACTGGTACTATC
GTTGCTTCTCCTGCTAAAGGTCAAGATTTTGAGCTTGCTGCAACTGAAGTTAAAGTTGTAGGTTGGGTTGAAGACGCAGA
AACTTACCCAATGGCTAAGACTCGTCACTCAATTGAATATTTACGTGAAGTTGCACACCTTCGCCCACGTACTAACGTGA
TCGGTGCGGTTGCACGTGTTCGTAACTGTCTATCTCAAGCGATTCACCGTTTCTACCACGAGCAAGGCTACTTCTGGATG
TCTGCTCCACTTATCACTGCATCTGATGCAGAAGGTGCTGGTGAAATGTTCCGTGTTTCTACTTTAGACCATGCGAACCT
TCCTTTAGATGACAAAGGCAATGTTGATTACGACAAAGATTTCTTTGGTAAAGAAACATTCCTAACCGTATCTGGTCAAC
TTAATGCGGAAACTTACGCTTGTGCACTAAGCAAAGTTTACACATTCGGTCCTACTTTCCGTGCTGAAAACTCACACACA
AGTCGCCACCTAGCTGAATTCTGGATGGTTGAGCCTGAAGTTGCTTTCGCTACTCTTGATGACGTAGCTAAGCTAGCTGA
AGACATGCTTAAGTATGTATTCGAAGCCGTTCTTGCTGAGCGTCGTGATGACCTTGAGTTCTTTGCTTCTCGCATCGACA
AACAAGCAATCACTCGTCTAGAGCAATTCGTAAGCTCTGATTTCGCACAAGTAGACTACACTGACGCTATCCAAATCCTT
AAAGATTCTGGTCGTGACTTTGAGTTTGATGTTGAGTGGGGCATCGATATGTCTTCTGAACATGAGCGTTACCTTGCTGA
AGAACACTTCAAAGCACCAGTTATCGTTAAAAACTACCCGAAAGACATCAAAGCATTCTACATGCGTCAAAATGACGATG
GTAAAACAGTTGCTGCAATGGATGTTCTTGCACCTGGCATTGGTGAGATCATTGGTGGTTCTCAACGTGAAGAGCGTTTA
GACATTCTTGATGCACGTATGATTGAAATGGGTATCGACCCTGAGCACATGAGCTGGTACCGCGATTTACGTCGTTACGG
CACAGTTCCTCATGCTGGTTTCGGTCTTGGCTTTGAGCGTCTAGTATCTTACGTAACTGGTATGGGCAACGTTCGTGACG
TTATCCCGTTCCCACGTACTCCACGTTCAGCTAACTTCTAA

Upstream 100 bases:

>100_bases
AGCGTAACAACACTTGATGCGAGCTATAAGAAAGGTAATATGTCACTCTTGAAATAAAAATATTCGTGCATGTGGCACAA
CAATGGAGAATGTATTTAAC

Downstream 100 bases:

>100_bases
TTCGTATTATCTTTATTGAGATAACCTAATTAGCAAGTAATGAATACAAAAATGGCGACCACATTGGTCGCCATTTTTTC
AATAAGTATTCATTACCAAA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTYAPVTDVLSGKLAVDSEVTVRGWIRSRRDSKAGISFLAVYDGSCFDPIQAVVPNDLNNYNDEVLKLTTGCSVEVTGTI
VASPAKGQDFELAATEVKVVGWVEDAETYPMAKTRHSIEYLREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGYFWM
SAPLITASDAEGAGEMFRVSTLDHANLPLDDKGNVDYDKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHT
SRHLAEFWMVEPEVAFATLDDVAKLAEDMLKYVFEAVLAERRDDLEFFASRIDKQAITRLEQFVSSDFAQVDYTDAIQIL
KDSGRDFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYPKDIKAFYMRQNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DILDARMIEMGIDPEHMSWYRDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF

Sequences:

>Translated_466_residues
MTYAPVTDVLSGKLAVDSEVTVRGWIRSRRDSKAGISFLAVYDGSCFDPIQAVVPNDLNNYNDEVLKLTTGCSVEVTGTI
VASPAKGQDFELAATEVKVVGWVEDAETYPMAKTRHSIEYLREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGYFWM
SAPLITASDAEGAGEMFRVSTLDHANLPLDDKGNVDYDKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHT
SRHLAEFWMVEPEVAFATLDDVAKLAEDMLKYVFEAVLAERRDDLEFFASRIDKQAITRLEQFVSSDFAQVDYTDAIQIL
KDSGRDFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYPKDIKAFYMRQNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DILDARMIEMGIDPEHMSWYRDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF
>Mature_465_residues
TYAPVTDVLSGKLAVDSEVTVRGWIRSRRDSKAGISFLAVYDGSCFDPIQAVVPNDLNNYNDEVLKLTTGCSVEVTGTIV
ASPAKGQDFELAATEVKVVGWVEDAETYPMAKTRHSIEYLREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGYFWMS
APLITASDAEGAGEMFRVSTLDHANLPLDDKGNVDYDKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHTS
RHLAEFWMVEPEVAFATLDDVAKLAEDMLKYVFEAVLAERRDDLEFFASRIDKQAITRLEQFVSSDFAQVDYTDAIQILK
DSGRDFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYPKDIKAFYMRQNDDGKTVAAMDVLAPGIGEIIGGSQREERLD
ILDARMIEMGIDPEHMSWYRDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=463, Percent_Identity=42.7645788336933, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI4758762, Length=447, Percent_Identity=29.7539149888143, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI45439306, Length=342, Percent_Identity=28.0701754385965, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=77.4678111587983, Blast_Score=781, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=475, Percent_Identity=21.6842105263158, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789256, Length=475, Percent_Identity=21.2631578947368, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=34.8623853211009, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=451, Percent_Identity=29.2682926829268, Blast_Score=191, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17556372, Length=430, Percent_Identity=30.6976744186047, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=481, Percent_Identity=26.8191268191268, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319872, Length=471, Percent_Identity=37.5796178343949, Blast_Score=306, Evalue=7e-84,
Organism=Saccharomyces cerevisiae, GI6321807, Length=458, Percent_Identity=32.9694323144105, Blast_Score=206, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6323011, Length=494, Percent_Identity=24.8987854251012, Blast_Score=113, Evalue=7e-26,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=35.3448275862069, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI19921528, Length=458, Percent_Identity=29.4759825327511, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=27.9883381924198, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52445; Mature: 52313

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYAPVTDVLSGKLAVDSEVTVRGWIRSRRDSKAGISFLAVYDGSCFDPIQAVVPNDLNN
CCCCCCHHHHCCCEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCC
YNDEVLKLTTGCSVEVTGTIVASPAKGQDFELAATEVKVVGWVEDAETYPMAKTRHSIEY
CCCCEEEEECCCEEEEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHH
LREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGYFWMSAPLITASDAEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEEE
TLDHANLPLDDKGNVDYDKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHT
ECCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCH
SRHLAEFWMVEPEVAFATLDDVAKLAEDMLKYVFEAVLAERRDDLEFFASRIDKQAITRL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EQFVSSDFAQVDYTDAIQILKDSGRDFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYP
HHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRQNDDGKTVAAMDVLAPGIGEIIGGSQREERLDILDARMIEMGIDPEHMSWY
CHHHEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TYAPVTDVLSGKLAVDSEVTVRGWIRSRRDSKAGISFLAVYDGSCFDPIQAVVPNDLNN
CCCCCHHHHCCCEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCC
YNDEVLKLTTGCSVEVTGTIVASPAKGQDFELAATEVKVVGWVEDAETYPMAKTRHSIEY
CCCCEEEEECCCEEEEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHH
LREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGYFWMSAPLITASDAEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEEE
TLDHANLPLDDKGNVDYDKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHT
ECCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCH
SRHLAEFWMVEPEVAFATLDDVAKLAEDMLKYVFEAVLAERRDDLEFFASRIDKQAITRL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EQFVSSDFAQVDYTDAIQILKDSGRDFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYP
HHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRQNDDGKTVAAMDVLAPGIGEIIGGSQREERLDILDARMIEMGIDPEHMSWY
CHHHEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA