Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 59711740

GI number: 59711740

Start: 1255054

End: 1257063

Strand: Reverse

Name: hlyB [H]

Synonym: VF_1133

Alternate gene names: 59711740

Gene position: 1257063-1255054 (Counterclockwise)

Preceding gene: 59711745

Following gene: 59711737

Centisome position: 43.38

GC content: 40.55

Gene sequence:

>2010_bases
ATGAAAGAGAGATACAACATGAACAGTTCGGTAGTTCGTCGCATGTACGCAGGATTCTCCTTAATTGTTATCCTATTTAT
TACGACGGTTATCTTAATGCTCAACGGAACGAGCAATATTCACAAACAGATGCAATCTGTCTCTTCAGAATCCATGCCTT
TAGTGAGCTTATCAAACGAAACAAGCGTCTCCTTACTTGCTGCTGATAAGTCATTTAAAGATTTCCTTACTACTCGCGAT
ACTATTCAAATGCAGCAAGCTCGTGAGCAATTTTCTGTTGCAGAAACCAAATTTAAAAATACCTTTAAACAACTTATCAA
TACCGCTCAACAAAAAAACACGGGCGCACAACAACGTTCAGAACTGGCTAAAATAGAAAGCGCTTATTTCAATGAAGCAA
AAGTAGCAATGGATAACTACCAAGCCCTACTGACTGCTGAAGATGAAAAACAACAAGCGATCCGTAACTTTCAACGTCTT
TACACTGAGTTAAGTGTACGTATGAAAGAATACATTAATGACCAAGAAAGTATCGCTGTTAAGATGATGGCGAAAAGCTA
CTTCGTGAAACTAGAAGACGCAGAGCTGATTACTTCGGATGCATTAGCAAGTAGCGATATCGCATTGGTTAATAAAGCCG
TTAATCAAAACAAAAAAGCGGTTACGCACTTAAACTACGCTTACCGTGGGCTAGCAAACCAATTGCCTGAGCTAAAAGGC
ACATTTGATGATTCAGTAAAGCAATTCAGCGCTGAAGTAGGACAAAAAGAAGGGATTCTAAATACTCACTTTGCCTACTT
AACGGCTAAAGATGCGTTGTACACCAACATCTCAAACCTTGCTCAGCAAATTGATAAAGCCATCACCCTGCTGACTTCAT
TTAATCAATTAGCAAACCAAGATTTACAAAACTCACTGCAACAAGCAGACACCATTTACCGACAAAGCCTTTATAAAGGG
ATTGCACTGGGTGTGGTTGTTTCTCTGTTAGCGACCTTTATTGGTTTTAACCTAGCGACATCAGTTCGTACCCCACTACA
AAATATGCTTAAAATCTTAGAGTCATTAACCTCTGGCGATATGACTCAGCGTATTGAAACCAAACGAAATACCGAATTTA
GCCGTGTATCTCGTCATATCAATACCCTTGCCGACAACCTACAAAAAGTATTAATTCAGTTAAGTGGGGCTTCTGATGAA
CTGACTGAAGTTGCGCAAAATAACAACGCCACCGCAGAGAAAGCGAAACAACAACTACTGAACCAACGTGAACAAACCAC
AAGCGTTGCAGCGGCAATGACAGAGATGGAACACTCGGTTGTAGAAGTTGCATCAAGCTCAGAAAGTTCACTACTAAAAG
TACAAGAAGTAGAAGCCGCTTCTGAGCACGGTCAACAAGTCATGAAAAACAACTTAGAGACCATTGAGCAACTTTCTTCT
CGCTTGGATGAATCAGTACAAGCCGTATCCAACCTACAGAAAGTAAGTTGCGAGATTGGCTCAATTTTAGATGTGATTAA
TAACATTGCTGAGCAAACCAACCTACTTGCACTTAATGCCGCTATCGAAGCAGCTCGTGCCGGCGAACAAGGCCGTGGCT
TTGCGGTTGTTGCTGATGAAGTGCGTATTCTTGCTCAACGTACAGCAAAATCAACTTCTGAAATTGAAGTAATGATTGCT
AACCTTCAATCAAGCTCAAAAACCACCACGACAGTGATTGAAAGCTGTGTTGAAGACATGCAACAAAGCGTCACTCAAAC
CAACGAAGCCAATAATGCGATGGTGATGATCCAAAACTTAATTGAAGAGATCAGCCACATGAGTAATCACATTTCTCAAG
CGGCAAACGAGCAAAGTGCAACAACAACTGAGATTGCACGTAGCTTAGAGGATATCAGTCACATTGCTGAAAATAACCAA
GAAGCGATGAACGACATTGCTAATGTAAGCCAAACATTAAATGAACTGGCTCACCAGCAAAGTGATATTGTGCATCAATT
TAAAGTGTAA

Upstream 100 bases:

>100_bases
ATTTGTGTGACGAGTTAATCATATCATGAATAATCACTGTAACCATTTTAAGACTCGCAAGCAAAAAAATCATCATTGCA
CAATCTTAATACCCTTTTAG

Downstream 100 bases:

>100_bases
TTATCTTAGATAAGCAATGTCACAAACAAAAAAGGTGGATAAATTATCCACCTTTTTTATTACGCTTTACTCTAAAACGA
ACAATTAACGAGAAAACAGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MKERYNMNSSVVRRMYAGFSLIVILFITTVILMLNGTSNIHKQMQSVSSESMPLVSLSNETSVSLLAADKSFKDFLTTRD
TIQMQQAREQFSVAETKFKNTFKQLINTAQQKNTGAQQRSELAKIESAYFNEAKVAMDNYQALLTAEDEKQQAIRNFQRL
YTELSVRMKEYINDQESIAVKMMAKSYFVKLEDAELITSDALASSDIALVNKAVNQNKKAVTHLNYAYRGLANQLPELKG
TFDDSVKQFSAEVGQKEGILNTHFAYLTAKDALYTNISNLAQQIDKAITLLTSFNQLANQDLQNSLQQADTIYRQSLYKG
IALGVVVSLLATFIGFNLATSVRTPLQNMLKILESLTSGDMTQRIETKRNTEFSRVSRHINTLADNLQKVLIQLSGASDE
LTEVAQNNNATAEKAKQQLLNQREQTTSVAAAMTEMEHSVVEVASSSESSLLKVQEVEAASEHGQQVMKNNLETIEQLSS
RLDESVQAVSNLQKVSCEIGSILDVINNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRILAQRTAKSTSEIEVMIA
NLQSSSKTTTTVIESCVEDMQQSVTQTNEANNAMVMIQNLIEEISHMSNHISQAANEQSATTTEIARSLEDISHIAENNQ
EAMNDIANVSQTLNELAHQQSDIVHQFKV

Sequences:

>Translated_669_residues
MKERYNMNSSVVRRMYAGFSLIVILFITTVILMLNGTSNIHKQMQSVSSESMPLVSLSNETSVSLLAADKSFKDFLTTRD
TIQMQQAREQFSVAETKFKNTFKQLINTAQQKNTGAQQRSELAKIESAYFNEAKVAMDNYQALLTAEDEKQQAIRNFQRL
YTELSVRMKEYINDQESIAVKMMAKSYFVKLEDAELITSDALASSDIALVNKAVNQNKKAVTHLNYAYRGLANQLPELKG
TFDDSVKQFSAEVGQKEGILNTHFAYLTAKDALYTNISNLAQQIDKAITLLTSFNQLANQDLQNSLQQADTIYRQSLYKG
IALGVVVSLLATFIGFNLATSVRTPLQNMLKILESLTSGDMTQRIETKRNTEFSRVSRHINTLADNLQKVLIQLSGASDE
LTEVAQNNNATAEKAKQQLLNQREQTTSVAAAMTEMEHSVVEVASSSESSLLKVQEVEAASEHGQQVMKNNLETIEQLSS
RLDESVQAVSNLQKVSCEIGSILDVINNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRILAQRTAKSTSEIEVMIA
NLQSSSKTTTTVIESCVEDMQQSVTQTNEANNAMVMIQNLIEEISHMSNHISQAANEQSATTTEIARSLEDISHIAENNQ
EAMNDIANVSQTLNELAHQQSDIVHQFKV
>Mature_669_residues
MKERYNMNSSVVRRMYAGFSLIVILFITTVILMLNGTSNIHKQMQSVSSESMPLVSLSNETSVSLLAADKSFKDFLTTRD
TIQMQQAREQFSVAETKFKNTFKQLINTAQQKNTGAQQRSELAKIESAYFNEAKVAMDNYQALLTAEDEKQQAIRNFQRL
YTELSVRMKEYINDQESIAVKMMAKSYFVKLEDAELITSDALASSDIALVNKAVNQNKKAVTHLNYAYRGLANQLPELKG
TFDDSVKQFSAEVGQKEGILNTHFAYLTAKDALYTNISNLAQQIDKAITLLTSFNQLANQDLQNSLQQADTIYRQSLYKG
IALGVVVSLLATFIGFNLATSVRTPLQNMLKILESLTSGDMTQRIETKRNTEFSRVSRHINTLADNLQKVLIQLSGASDE
LTEVAQNNNATAEKAKQQLLNQREQTTSVAAAMTEMEHSVVEVASSSESSLLKVQEVEAASEHGQQVMKNNLETIEQLSS
RLDESVQAVSNLQKVSCEIGSILDVINNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRILAQRTAKSTSEIEVMIA
NLQSSSKTTTTVIESCVEDMQQSVTQTNEANNAMVMIQNLIEEISHMSNHISQAANEQSATTTEIARSLEDISHIAENNQ
EAMNDIANVSQTLNELAHQQSDIVHQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=422, Percent_Identity=28.6729857819905, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI2367378, Length=334, Percent_Identity=27.5449101796407, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788195, Length=300, Percent_Identity=28, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788194, Length=299, Percent_Identity=26.7558528428094, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1789453, Length=249, Percent_Identity=31.3253012048193, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 74106; Mature: 74106

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERYNMNSSVVRRMYAGFSLIVILFITTVILMLNGTSNIHKQMQSVSSESMPLVSLSNE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCC
TSVSLLAADKSFKDFLTTRDTIQMQQAREQFSVAETKFKNTFKQLINTAQQKNTGAQQRS
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ELAKIESAYFNEAKVAMDNYQALLTAEDEKQQAIRNFQRLYTELSVRMKEYINDQESIAV
HHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KMMAKSYFVKLEDAELITSDALASSDIALVNKAVNQNKKAVTHLNYAYRGLANQLPELKG
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHCC
TFDDSVKQFSAEVGQKEGILNTHFAYLTAKDALYTNISNLAQQIDKAITLLTSFNQLANQ
CHHHHHHHHHHHHHHHCCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLQNSLQQADTIYRQSLYKGIALGVVVSLLATFIGFNLATSVRTPLQNMLKILESLTSGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MTQRIETKRNTEFSRVSRHINTLADNLQKVLIQLSGASDELTEVAQNNNATAEKAKQQLL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
NQREQTTSVAAAMTEMEHSVVEVASSSESSLLKVQEVEAASEHGQQVMKNNLETIEQLSS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDESVQAVSNLQKVSCEIGSILDVINNIAEQTNLLALNAAIEAARAGEQGRGFAVVADE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHH
VRILAQRTAKSTSEIEVMIANLQSSSKTTTTVIESCVEDMQQSVTQTNEANNAMVMIQNL
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IEEISHMSNHISQAANEQSATTTEIARSLEDISHIAENNQEAMNDIANVSQTLNELAHQQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
SDIVHQFKV
HHHHHHHCC
>Mature Secondary Structure
MKERYNMNSSVVRRMYAGFSLIVILFITTVILMLNGTSNIHKQMQSVSSESMPLVSLSNE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCC
TSVSLLAADKSFKDFLTTRDTIQMQQAREQFSVAETKFKNTFKQLINTAQQKNTGAQQRS
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ELAKIESAYFNEAKVAMDNYQALLTAEDEKQQAIRNFQRLYTELSVRMKEYINDQESIAV
HHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KMMAKSYFVKLEDAELITSDALASSDIALVNKAVNQNKKAVTHLNYAYRGLANQLPELKG
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHCC
TFDDSVKQFSAEVGQKEGILNTHFAYLTAKDALYTNISNLAQQIDKAITLLTSFNQLANQ
CHHHHHHHHHHHHHHHCCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLQNSLQQADTIYRQSLYKGIALGVVVSLLATFIGFNLATSVRTPLQNMLKILESLTSGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MTQRIETKRNTEFSRVSRHINTLADNLQKVLIQLSGASDELTEVAQNNNATAEKAKQQLL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
NQREQTTSVAAAMTEMEHSVVEVASSSESSLLKVQEVEAASEHGQQVMKNNLETIEQLSS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDESVQAVSNLQKVSCEIGSILDVINNIAEQTNLLALNAAIEAARAGEQGRGFAVVADE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHH
VRILAQRTAKSTSEIEVMIANLQSSSKTTTTVIESCVEDMQQSVTQTNEANNAMVMIQNL
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IEEISHMSNHISQAANEQSATTTEIARSLEDISHIAENNQEAMNDIANVSQTLNELAHQQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
SDIVHQFKV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]