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The map label for this gene is tcpI [H]

Identifier: 59711745

GI number: 59711745

Start: 1260342

End: 1262204

Strand: Reverse

Name: tcpI [H]

Synonym: VF_1138

Alternate gene names: 59711745

Gene position: 1262204-1260342 (Counterclockwise)

Preceding gene: 59711747

Following gene: 59711740

Centisome position: 43.56

GC content: 36.61

Gene sequence:

>1863_bases
ATGATTAAAAAAATAACTTTAATTTTCTGCTTAGTTATATTAACAACGCTTGCTTTAACACTTGTTGCATCAGGAAGTTT
CTTAAAATCATACAAAGAAAACAACATGACGCATGCCAGTAAGATTGCACTTGATGTAACTCAAGCTAATTTTAATGCGG
CAATAAATGGACTTTATGGCTCAATAAAATCATTATCAGCTGCCATTGAATTAGACCCAAACCAACCATTTGACGAAAAG
CTTATCTTAGGCAACATTCAAGATATTGTTAAATCAAATAAAACATACACTAATGTTATCTTATCCAATTTAAATGGTGA
TGTTTTCTCTGTTGCTGCTAATGGTTGGCATCCAACATTTAACGCTATCAAAGGTAATAGAGAGTGGTTTAACTCTATTA
TGCAAGATAAAAAAGAAGCTAATATATCAACACCTTACCTTTCTAACAGTGGAATATATGAAATAACAGCGAGTGCTCCG
CTTTTATTCAATAATGAAATTGTTGGTGTTATTGCTGTTGGGGTTAACTTGAATGTATTAATACCAGATAGTGGTATTGA
ATTCGCTTTAACAACTCAGAGTGGTCATATTGTTGCTATTGATAGTAATTCACCTGATTGGCTAAATAAGAATTTATTCG
AAATTAGACCAGAATATAAAGGGGTGACAGACAAACCAATGTTTATTGATGCTGGGGATAACGAGTTTTTTAGCTTAACA
AAGTTGCCACTTTCGCATGGACTTGTTGGTTACGTATTTACAAACCAAACCACCACCTTTGAAAATGCTCAAAATATCCG
AACAGCGTTAATCAGTGTTTTAGTTATTCTTGGTTTGGTTTTGACTCTTGCTCAATTTATTGTGGTTCGTAAAGAGCTTT
CACAGATCCCAAATGTAGTGAGCAATATTCAACTAATGGCGAGTGGTGATTTTACTAATCTATCCATTCCTAAAACAGGA
AACGAAATTGATTTAATCACAGAATCATTAGAGAGCTTACAATCACGCATTTCTGGTGTAATGACAACAACAAACACCAT
TATGTATAAGCTATCTGAACATCAAGAACAAATCTCTGAGGTGACTAACAATAACGTTACGCGATCTGAATCTGAGCTAC
AACACATTGATCAAGTCGCTGCAGCTATTACTGAAATGGCTACCACAGCAAACGATATTGCCGCGAATGCACTATCTGCT
GAAGGAGAGACGAGCACAACATTAGTTCTTTCCTCTGATAGCTTAAAAACGTTACAAGAGTCCTCTTCTATCGTTGACCG
CGTTTCATCATCGGTTAAAGAGTCATCTTGCATTATTGAAGAGTTAAAAATCCTATCAGACAACATCAGCTCAGTGGTTG
ACGTTATTGGTAATATCTCAGACCAAACAAACCTACTCGCTCTAAACGCTGCAATTGAAGCGGCACGAGCTGGTGAGCAA
GGACGTGGCTTTGCGGTAGTTGCAGATGAAGTGAGAGCTTTGGCGGTTAAAACACAAGATTCAACAGCCAATATTCAAAC
GATCATTGCGACTCTACAAACAGAAGCGACAAGAGCCGTTGATGCGATGGAAAACAACTTACAGTTAACCAACGATTTAG
CGAAAATATCGGATAAAATTGAAGACGCATTCAACAATATTTCAGAGAAAGTAACTCTGCTTGTTGATATTAACTCATCA
GTTGCGACCGCTTCTGAAGAGCAATCAATCGTAAACCAAAACATCGCACATAATGTGGAAGACATTAAAAACATGGTTGT
CGACAACTTATCAGGCGTGACTCAAGCGATTGACTCAAATACAGAAATGGTTGCCTTAGTTGAAGAATTAAAAGCAGAAG
TCAGCTTCTTCAAAGTGTCTTAA

Upstream 100 bases:

>100_bases
AATAATTATAAAACCTTTTAAATGAGCGAAAATTTTAATTTCAAACCATAAAATAGCAGTGTAATGTGCGCAATCTATAA
CCATTATTAACCTTCAAAAA

Downstream 100 bases:

>100_bases
TTAATATATTCAACACAAAATAAAAGCCCTTCACTCAACGAGATGAAGGGCTTTTTTATGATTCTAAGTAATTAAGAGAT
TACCAACCTAGTAGGCTTTT

Product: methyl-accepting chemotaxis protein, TcpI-related

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MIKKITLIFCLVILTTLALTLVASGSFLKSYKENNMTHASKIALDVTQANFNAAINGLYGSIKSLSAAIELDPNQPFDEK
LILGNIQDIVKSNKTYTNVILSNLNGDVFSVAANGWHPTFNAIKGNREWFNSIMQDKKEANISTPYLSNSGIYEITASAP
LLFNNEIVGVIAVGVNLNVLIPDSGIEFALTTQSGHIVAIDSNSPDWLNKNLFEIRPEYKGVTDKPMFIDAGDNEFFSLT
KLPLSHGLVGYVFTNQTTTFENAQNIRTALISVLVILGLVLTLAQFIVVRKELSQIPNVVSNIQLMASGDFTNLSIPKTG
NEIDLITESLESLQSRISGVMTTTNTIMYKLSEHQEQISEVTNNNVTRSESELQHIDQVAAAITEMATTANDIAANALSA
EGETSTTLVLSSDSLKTLQESSSIVDRVSSSVKESSCIIEELKILSDNISSVVDVIGNISDQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAVKTQDSTANIQTIIATLQTEATRAVDAMENNLQLTNDLAKISDKIEDAFNNISEKVTLLVDINSS
VATASEEQSIVNQNIAHNVEDIKNMVVDNLSGVTQAIDSNTEMVALVEELKAEVSFFKVS

Sequences:

>Translated_620_residues
MIKKITLIFCLVILTTLALTLVASGSFLKSYKENNMTHASKIALDVTQANFNAAINGLYGSIKSLSAAIELDPNQPFDEK
LILGNIQDIVKSNKTYTNVILSNLNGDVFSVAANGWHPTFNAIKGNREWFNSIMQDKKEANISTPYLSNSGIYEITASAP
LLFNNEIVGVIAVGVNLNVLIPDSGIEFALTTQSGHIVAIDSNSPDWLNKNLFEIRPEYKGVTDKPMFIDAGDNEFFSLT
KLPLSHGLVGYVFTNQTTTFENAQNIRTALISVLVILGLVLTLAQFIVVRKELSQIPNVVSNIQLMASGDFTNLSIPKTG
NEIDLITESLESLQSRISGVMTTTNTIMYKLSEHQEQISEVTNNNVTRSESELQHIDQVAAAITEMATTANDIAANALSA
EGETSTTLVLSSDSLKTLQESSSIVDRVSSSVKESSCIIEELKILSDNISSVVDVIGNISDQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAVKTQDSTANIQTIIATLQTEATRAVDAMENNLQLTNDLAKISDKIEDAFNNISEKVTLLVDINSS
VATASEEQSIVNQNIAHNVEDIKNMVVDNLSGVTQAIDSNTEMVALVEELKAEVSFFKVS
>Mature_620_residues
MIKKITLIFCLVILTTLALTLVASGSFLKSYKENNMTHASKIALDVTQANFNAAINGLYGSIKSLSAAIELDPNQPFDEK
LILGNIQDIVKSNKTYTNVILSNLNGDVFSVAANGWHPTFNAIKGNREWFNSIMQDKKEANISTPYLSNSGIYEITASAP
LLFNNEIVGVIAVGVNLNVLIPDSGIEFALTTQSGHIVAIDSNSPDWLNKNLFEIRPEYKGVTDKPMFIDAGDNEFFSLT
KLPLSHGLVGYVFTNQTTTFENAQNIRTALISVLVILGLVLTLAQFIVVRKELSQIPNVVSNIQLMASGDFTNLSIPKTG
NEIDLITESLESLQSRISGVMTTTNTIMYKLSEHQEQISEVTNNNVTRSESELQHIDQVAAAITEMATTANDIAANALSA
EGETSTTLVLSSDSLKTLQESSSIVDRVSSSVKESSCIIEELKILSDNISSVVDVIGNISDQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAVKTQDSTANIQTIIATLQTEATRAVDAMENNLQLTNDLAKISDKIEDAFNNISEKVTLLVDINSS
VATASEEQSIVNQNIAHNVEDIKNMVVDNLSGVTQAIDSNTEMVALVEELKAEVSFFKVS

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=325, Percent_Identity=31.3846153846154, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788194, Length=365, Percent_Identity=28.7671232876712, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI2367378, Length=304, Percent_Identity=28.9473684210526, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1788195, Length=335, Percent_Identity=26.5671641791045, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789453, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 67033; Mature: 67033

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKITLIFCLVILTTLALTLVASGSFLKSYKENNMTHASKIALDVTQANFNAAINGLYG
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHEEEEEEECCHHHHHHHHHH
SIKSLSAAIELDPNQPFDEKLILGNIQDIVKSNKTYTNVILSNLNGDVFSVAANGWHPTF
HHHHCEEEEEECCCCCCCCHHHHCCHHHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCH
NAIKGNREWFNSIMQDKKEANISTPYLSNSGIYEITASAPLLFNNEIVGVIAVGVNLNVL
HHCCCCHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCEEECCCEEEEEEECCEEEEE
IPDSGIEFALTTQSGHIVAIDSNSPDWLNKNLFEIRPEYKGVTDKPMFIDAGDNEFFSLT
ECCCCCEEEEEECCCEEEEECCCCCCCCCCCHHEECCCCCCCCCCCEEEECCCCCEEEEE
KLPLSHGLVGYVFTNQTTTFENAQNIRTALISVLVILGLVLTLAQFIVVRKELSQIPNVV
ECHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNIQLMASGDFTNLSIPKTGNEIDLITESLESLQSRISGVMTTTNTIMYKLSEHQEQISE
HCEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECHHHEEHHHHHHHHHHH
VTNNNVTRSESELQHIDQVAAAITEMATTANDIAANALSAEGETSTTLVLSSDSLKTLQE
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHH
SSSIVDRVSSSVKESSCIIEELKILSDNISSVVDVIGNISDQTNLLALNAAIEAARAGEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCC
GRGFAVVADEVRALAVKTQDSTANIQTIIATLQTEATRAVDAMENNLQLTNDLAKISDKI
CCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EDAFNNISEKVTLLVDINSSVATASEEQSIVNQNIAHNVEDIKNMVVDNLSGVTQAIDSN
HHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
TEMVALVEELKAEVSFFKVS
CHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MIKKITLIFCLVILTTLALTLVASGSFLKSYKENNMTHASKIALDVTQANFNAAINGLYG
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHEEEEEEECCHHHHHHHHHH
SIKSLSAAIELDPNQPFDEKLILGNIQDIVKSNKTYTNVILSNLNGDVFSVAANGWHPTF
HHHHCEEEEEECCCCCCCCHHHHCCHHHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCH
NAIKGNREWFNSIMQDKKEANISTPYLSNSGIYEITASAPLLFNNEIVGVIAVGVNLNVL
HHCCCCHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCEEECCCEEEEEEECCEEEEE
IPDSGIEFALTTQSGHIVAIDSNSPDWLNKNLFEIRPEYKGVTDKPMFIDAGDNEFFSLT
ECCCCCEEEEEECCCEEEEECCCCCCCCCCCHHEECCCCCCCCCCCEEEECCCCCEEEEE
KLPLSHGLVGYVFTNQTTTFENAQNIRTALISVLVILGLVLTLAQFIVVRKELSQIPNVV
ECHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNIQLMASGDFTNLSIPKTGNEIDLITESLESLQSRISGVMTTTNTIMYKLSEHQEQISE
HCEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECHHHEEHHHHHHHHHHH
VTNNNVTRSESELQHIDQVAAAITEMATTANDIAANALSAEGETSTTLVLSSDSLKTLQE
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHH
SSSIVDRVSSSVKESSCIIEELKILSDNISSVVDVIGNISDQTNLLALNAAIEAARAGEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCC
GRGFAVVADEVRALAVKTQDSTANIQTIIATLQTEATRAVDAMENNLQLTNDLAKISDKI
CCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EDAFNNISEKVTLLVDINSSVATASEEQSIVNQNIAHNVEDIKNMVVDNLSGVTQAIDSN
HHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
TEMVALVEELKAEVSFFKVS
CHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]