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The map label for this gene is engA [H]

Identifier: 59711240

GI number: 59711240

Start: 689442

End: 690944

Strand: Direct

Name: engA [H]

Synonym: VF_0633

Alternate gene names: 59711240

Gene position: 689442-690944 (Clockwise)

Preceding gene: 59711239

Following gene: 59711241

Centisome position: 23.79

GC content: 41.32

Gene sequence:

>1503_bases
ATGATTCCTGTTGTTGCTCTGGTAGGGCGTCCAAATGTTGGTAAATCGACGCTATTTAACCGTCTTACACGCACAAGGGA
TGCATTAGTTGCTGACTTTCCTGGTTTAACTCGTGACCGTAAATACGGACGAGCTAAGTTAGAAGAGCAAGAATTCATTC
TGATTGATACCGGCGGTATCGATGGAACAGAACAAGGCGTTGAAACTAAAATGGCAGAACAGTCATTAGCTGCAATTGAA
GAAGCTGATGTTGTGCTATTTATGGTTGATGGTCGTGCTGGTTTAACATCTGCAGATGAAGCCATCGCAAAACACTTACG
TTCACGTGAAAAGCCAACGTTCTTAGTGGTTAACAAGATCGATGGTATTGATGCAGATGCTGCAAGTGCAGAGTTCTGGC
AATTAGGTATGAACAAAGTATACCAAATTGCAGCTTCACACGGTCGTGGTGTAACGTCTTTACTTGAACTTGCTCTAGCT
CCTTTTATGGAAGAGCTTGTTGAAGAGTCTTTGAAAGATGAAAACGGTGAAATCACTGATTTAACTGAATTTGAAGATTT
TGAAGACGAAGAGAAAGATCTAACTGAAGAAGATGCAGAGAAAGATTTTGCTCGCCTTCAGGATCAACCGATTAAACTTG
CTATCATTGGCCGTCCAAACGTAGGTAAATCGACACTGACTAACCGTATTCTTGGTGAAGAACGTGTGGTGGTTTACGAT
ATGCCTGGTACAACTCGTGACTCTATTTACATTCCTATGGAACGTGAAGGTCAAGAATACGTATTAATTGATACTGCGGG
TGTTCGTCGTCGTGGCCGTATTAACGAAACCGTAGAAAAATTCTCTGTAATCAAAACATTAAAAGCCGTTGAAGATGCAA
ACGTTGTTCTACTGGTGATTGATGCTCGTGAAAACATCTCAGATCAAGATTTAAGTCTACTTGGCTTTGCACTGAATGCG
GGTCGTTCATTAGTAATTGCTGTGAACAAGTGGGATGGTTTAGATAACGATGTGAAAGAAAAAGTAAAATCTGAACTTGA
TCGCCGTTTAGGTTTTGTTGATTTTGCTCGTATTCACTTTATTTCTGCACTACACGGTACAGGTGTTGGTCACTTGTATG
AATCGGTTCAAGAAGCATACGTTTCTGCGACTAAGCGTGTTGGTACTTCTGTTTTAACTCGTATCATGAAAATGGCACAA
GATGATCACCAACCACCATTGGTTCGTGGCCGTCGTGTGAAGCTAAAATACGCTCACGCAGGTGGTTACAATCCACCGCT
TATCGTTATTCACGGTAACCAAGTGAAAGAATTACCATCTTCATACAAACGTTTCTTAATGAACTACTACCGTAAGTCTT
TAGAAATTATGGGCACTCCAATTCGTATTCAATTCCAGAATAGCGAAAACCCATTTGAAGATCGTGGTGGCAAACTAACT
ATGTCGCAAGAGCGTCAACGCAAGCGTCTGTTAGGTGCAGTGAAAAACCGCAACAAGAAGTAA

Upstream 100 bases:

>100_bases
ATCCAATTTGGTGATGGCTTTATGTGTAATCAATCAGTCAAAACCATCATCAAATTGGTATTAGCTCGCGCTATGCCTAT
GATTAAATAAAGAGGTATAT

Downstream 100 bases:

>100_bases
TCCAGAGTTACGTTCTTAAATGTATATTAAATAATAAAACGCCCATCTAGTTGTTGGGCGTTTTTTTTAGGTAAAAATCA
TGACTCAATTAGCAGCAACT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGIDGTEQGVETKMAEQSLAAIE
EADVVLFMVDGRAGLTSADEAIAKHLRSREKPTFLVVNKIDGIDADAASAEFWQLGMNKVYQIAASHGRGVTSLLELALA
PFMEELVEESLKDENGEITDLTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYD
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAVEDANVVLLVIDARENISDQDLSLLGFALNA
GRSLVIAVNKWDGLDNDVKEKVKSELDRRLGFVDFARIHFISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRIMKMAQ
DDHQPPLVRGRRVKLKYAHAGGYNPPLIVIHGNQVKELPSSYKRFLMNYYRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
MSQERQRKRLLGAVKNRNKK

Sequences:

>Translated_500_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGIDGTEQGVETKMAEQSLAAIE
EADVVLFMVDGRAGLTSADEAIAKHLRSREKPTFLVVNKIDGIDADAASAEFWQLGMNKVYQIAASHGRGVTSLLELALA
PFMEELVEESLKDENGEITDLTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYD
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAVEDANVVLLVIDARENISDQDLSLLGFALNA
GRSLVIAVNKWDGLDNDVKEKVKSELDRRLGFVDFARIHFISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRIMKMAQ
DDHQPPLVRGRRVKLKYAHAGGYNPPLIVIHGNQVKELPSSYKRFLMNYYRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
MSQERQRKRLLGAVKNRNKK
>Mature_500_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGIDGTEQGVETKMAEQSLAAIE
EADVVLFMVDGRAGLTSADEAIAKHLRSREKPTFLVVNKIDGIDADAASAEFWQLGMNKVYQIAASHGRGVTSLLELALA
PFMEELVEESLKDENGEITDLTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYD
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAVEDANVVLLVIDARENISDQDLSLLGFALNA
GRSLVIAVNKWDGLDNDVKEKVKSELDRRLGFVDFARIHFISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRIMKMAQ
DDHQPPLVRGRRVKLKYAHAGGYNPPLIVIHGNQVKELPSSYKRFLMNYYRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
MSQERQRKRLLGAVKNRNKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=499, Percent_Identity=74.1482965931864, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=133, Percent_Identity=33.8345864661654, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=33.0645161290323, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=125, Percent_Identity=31.2, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=205, Percent_Identity=28.2926829268293, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 56063; Mature: 56063

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCEEEEECCCC
DGTEQGVETKMAEQSLAAIEEADVVLFMVDGRAGLTSADEAIAKHLRSREKPTFLVVNKI
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECC
DGIDADAASAEFWQLGMNKVYQIAASHGRGVTSLLELALAPFMEELVEESLKDENGEITD
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYD
CCCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEE
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAVEDANVVLLVI
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
DARENISDQDLSLLGFALNAGRSLVIAVNKWDGLDNDVKEKVKSELDRRLGFVDFARIHF
ECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
ISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRIMKMAQDDHQPPLVRGRRVKLKYAHA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEC
GGYNPPLIVIHGNQVKELPSSYKRFLMNYYRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCEEE
MSQERQRKRLLGAVKNRNKK
EHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCEEEEECCCC
DGTEQGVETKMAEQSLAAIEEADVVLFMVDGRAGLTSADEAIAKHLRSREKPTFLVVNKI
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECC
DGIDADAASAEFWQLGMNKVYQIAASHGRGVTSLLELALAPFMEELVEESLKDENGEITD
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYD
CCCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEE
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAVEDANVVLLVI
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
DARENISDQDLSLLGFALNAGRSLVIAVNKWDGLDNDVKEKVKSELDRRLGFVDFARIHF
ECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
ISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRIMKMAQDDHQPPLVRGRRVKLKYAHA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEC
GGYNPPLIVIHGNQVKELPSSYKRFLMNYYRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCEEE
MSQERQRKRLLGAVKNRNKK
EHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA