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The map label for this gene is ygdL [H]

Identifier: 59711195

GI number: 59711195

Start: 646360

End: 647169

Strand: Direct

Name: ygdL [H]

Synonym: VF_0588

Alternate gene names: 59711195

Gene position: 646360-647169 (Clockwise)

Preceding gene: 59711194

Following gene: 59711198

Centisome position: 22.31

GC content: 40.74

Gene sequence:

>810_bases
ATGCGCGAATTAACCACTCCTGCATCTGAAAGTTATGACCAACGTTTTGGTGGCACTCGCCGTTTGTATGGTAATAGTGA
AGTAGAAATTATGCGTGCAGCTCATGTATGTGTAGTTGGTATTGGTGGTGTGGGTTCTTGGGCTGTAGAAGCGCTAGTAC
GTACTGGTTTAGGTGAAATTACGTTAATCGATATGGATGACGTATGTGTGACGAATATTAACCGTCAAATTCATGCGATG
ACAGGTACGATTGGTCAAAGCAAAATTGAAGTCATGGCTGAGCGCATTAAATTAATTAACCCTGAGTGTAAGATTAATTT
AATCGATGATTTCATTACCCCTGAAAATCTATCTGAATACATCTCTAAAGAGTTTGATTACGTACTTGATGCCATTGATA
GCATGAAACCTAAAGCGGCATTACTGGCTTATTGTAAGAGCAATAAGATTAAAGTCATTACGACTGGTGGTGCAGGTGGT
CAAACGGATCCGACTCAAATTCAAATCACAGATTTAACTAAGACGATTCAAGATCCTTTGGCTAAGAAATTGCGTGATAC
GCTGCGTCGCCACCATAATTTTACTAAGAACCCTAAACGTAAATTTGGTATTGATTGTGTGTACTCAACTGAGCATTTGA
AATACCCACAAGCTGATGGCTCAGTATGTGCGACTAAAGCAACTGCTGAAGGTCCTAAGCGTATGGATTGTGCGAGTGGT
TTTGGTGCTGCTACGGTGGTAACGGCGACGTTTGGGTTTGTTGCTGTGTCGAGAATTGTAGAAAAATTGATTGAGAAACA
CAGTAAGTAG

Upstream 100 bases:

>100_bases
AGAATAATGTGTTGGCCGCTTGTATCGCTTAACACTTGATCTTCTAAAAAAGAGTGCGTATAAATCGTGCTCTTTTTTTG
TTTTTGAGTAAGGTAACCCC

Downstream 100 bases:

>100_bases
GGACTAGGGATTAGAAGTAAGGTACGAGTAAAAGCCTTTCTCGTACTTAGCTTCTTGAAGCGAAGCGTTCTCGTTCCTGC
TTTAAATTAAGCCGTTGATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MRELTTPASESYDQRFGGTRRLYGNSEVEIMRAAHVCVVGIGGVGSWAVEALVRTGLGEITLIDMDDVCVTNINRQIHAM
TGTIGQSKIEVMAERIKLINPECKINLIDDFITPENLSEYISKEFDYVLDAIDSMKPKAALLAYCKSNKIKVITTGGAGG
QTDPTQIQITDLTKTIQDPLAKKLRDTLRRHHNFTKNPKRKFGIDCVYSTEHLKYPQADGSVCATKATAEGPKRMDCASG
FGAATVVTATFGFVAVSRIVEKLIEKHSK

Sequences:

>Translated_269_residues
MRELTTPASESYDQRFGGTRRLYGNSEVEIMRAAHVCVVGIGGVGSWAVEALVRTGLGEITLIDMDDVCVTNINRQIHAM
TGTIGQSKIEVMAERIKLINPECKINLIDDFITPENLSEYISKEFDYVLDAIDSMKPKAALLAYCKSNKIKVITTGGAGG
QTDPTQIQITDLTKTIQDPLAKKLRDTLRRHHNFTKNPKRKFGIDCVYSTEHLKYPQADGSVCATKATAEGPKRMDCASG
FGAATVVTATFGFVAVSRIVEKLIEKHSK
>Mature_269_residues
MRELTTPASESYDQRFGGTRRLYGNSEVEIMRAAHVCVVGIGGVGSWAVEALVRTGLGEITLIDMDDVCVTNINRQIHAM
TGTIGQSKIEVMAERIKLINPECKINLIDDFITPENLSEYISKEFDYVLDAIDSMKPKAALLAYCKSNKIKVITTGGAGG
QTDPTQIQITDLTKTIQDPLAKKLRDTLRRHHNFTKNPKRKFGIDCVYSTEHLKYPQADGSVCATKATAEGPKRMDCASG
FGAATVVTATFGFVAVSRIVEKLIEKHSK

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=131, Percent_Identity=30.5343511450382, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789177, Length=261, Percent_Identity=66.2835249042146, Blast_Score=386, Evalue=1e-109,
Organism=Escherichia coli, GI1787048, Length=126, Percent_Identity=31.7460317460317, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082356, Length=130, Percent_Identity=32.3076923076923, Blast_Score=71, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321790, Length=211, Percent_Identity=27.9620853080569, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322825, Length=207, Percent_Identity=32.3671497584541, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24660640, Length=131, Percent_Identity=32.0610687022901, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29516; Mature: 29516

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELTTPASESYDQRFGGTRRLYGNSEVEIMRAAHVCVVGIGGVGSWAVEALVRTGLGEI
CCCCCCCCHHHHHHHCCCCEEECCCCHHHHHHHCEEEEEEECCCHHHHHHHHHHCCCCCE
TLIDMDDVCVTNINRQIHAMTGTIGQSKIEVMAERIKLINPECKINLIDDFITPENLSEY
EEEECCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEHHHCCCHHHHHHH
ISKEFDYVLDAIDSMKPKAALLAYCKSNKIKVITTGGAGGQTDPTQIQITDLTKTIQDPL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHH
AKKLRDTLRRHHNFTKNPKRKFGIDCVYSTEHLKYPQADGSVCATKATAEGPKRMDCASG
HHHHHHHHHHHCCCCCCCCHHHCCEEEECHHHCCCCCCCCCEEEECCCCCCCCHHHHHCC
FGAATVVTATFGFVAVSRIVEKLIEKHSK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRELTTPASESYDQRFGGTRRLYGNSEVEIMRAAHVCVVGIGGVGSWAVEALVRTGLGEI
CCCCCCCCHHHHHHHCCCCEEECCCCHHHHHHHCEEEEEEECCCHHHHHHHHHHCCCCCE
TLIDMDDVCVTNINRQIHAMTGTIGQSKIEVMAERIKLINPECKINLIDDFITPENLSEY
EEEECCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEHHHCCCHHHHHHH
ISKEFDYVLDAIDSMKPKAALLAYCKSNKIKVITTGGAGGQTDPTQIQITDLTKTIQDPL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHH
AKKLRDTLRRHHNFTKNPKRKFGIDCVYSTEHLKYPQADGSVCATKATAEGPKRMDCASG
HHHHHHHHHHHCCCCCCCCHHHCCEEEECHHHCCCCCCCCCEEEECCCCCCCCHHHHHCC
FGAATVVTATFGFVAVSRIVEKLIEKHSK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]