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The map label for this gene is dapB [H]

Identifier: 59711078

GI number: 59711078

Start: 503322

End: 504131

Strand: Direct

Name: dapB [H]

Synonym: VF_0471

Alternate gene names: 59711078

Gene position: 503322-504131 (Clockwise)

Preceding gene: 59711077

Following gene: 59711079

Centisome position: 17.37

GC content: 40.12

Gene sequence:

>810_bases
ATGGTAAGAGTAGCAATTGCTGGCGCAGCAGGAAGAATGGGTCGCAACTTAATAAAAGCAGTTAATGGTTCTCAGTTTGC
TGTTCTTGCAGCAGCGAGTGAACGCCCAGAGTCGAGTCTTATTGGCGTTGATGTTGGTGAAATGGCTGGGTTAGGTAAAT
CAGGCATTCTTATTGTTGATGATTTAGCTAAAGTGACAGATGACTTTGATGTCATTATTGATTTTACCCTTCCTATTTCA
ACATTAAAAAATATAGAACTTTGCCAAGAACATAATAAAGCGATTGTTATTGGTACAACAGGTTTTAGCGAGCCTGGAAA
AGAAATTATTGATCAAGCATCGAAAGAAATTCCAGTAGTTATGGCTCCAAATTACAGTGTTGGCGTAAACCTTGTATTTA
AACTGCTAGAAAAAGCAGCAAAGGTCATGGGGGATTATTGCGATATTGAAATCGTTGAAGCTCATCACCGCTATAAAGTC
GATGCACCTTCAGGTACAGCGATTGGAATGGGAGAGGCGATTGCTGGTGCCATGGGTAACAAATTAGAAGATGTGGCTGT
ATATGCTAGAGAAGGCATTACTGGTGAAAGAAGCAAAGATGAAATTGGTTTTGCTACCATTCGAGCTGGTGATATTGTCG
GTGAGCATACTGCTATGTTTGCAGATATTGGCGAGAGAGTTGAGATAACGCATAAAGCGACGGATCGTATGACTTTTGCT
AATGGTGCCGTGAGAGCTTCTCATTGGCTTCATAAGAAAGAACCTGGTTTTTATACCATGCATGATGTATTAAATTTGGA
TCAGATTTAA

Upstream 100 bases:

>100_bases
AGAATTGCAAATCAAAACGGTATCTTAATACTTCACATAGTAGTGAATAAAAATTTAAGATAGAGTGCAAGGATGCGTAT
TTAAAGAAGCGGAGATCAAA

Downstream 100 bases:

>100_bases
TTATTACTAAGCCCGAATCAATGTGATTCGGGCTTTTTTTTAACTAAAGCCCTGTGATGGTAATGACTTGAAGGGGAGAT
ACTAACTATTTATCTTTAAT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MVRVAIAGAAGRMGRNLIKAVNGSQFAVLAAASERPESSLIGVDVGEMAGLGKSGILIVDDLAKVTDDFDVIIDFTLPIS
TLKNIELCQEHNKAIVIGTTGFSEPGKEIIDQASKEIPVVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIVEAHHRYKV
DAPSGTAIGMGEAIAGAMGNKLEDVAVYAREGITGERSKDEIGFATIRAGDIVGEHTAMFADIGERVEITHKATDRMTFA
NGAVRASHWLHKKEPGFYTMHDVLNLDQI

Sequences:

>Translated_269_residues
MVRVAIAGAAGRMGRNLIKAVNGSQFAVLAAASERPESSLIGVDVGEMAGLGKSGILIVDDLAKVTDDFDVIIDFTLPIS
TLKNIELCQEHNKAIVIGTTGFSEPGKEIIDQASKEIPVVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIVEAHHRYKV
DAPSGTAIGMGEAIAGAMGNKLEDVAVYAREGITGERSKDEIGFATIRAGDIVGEHTAMFADIGERVEITHKATDRMTFA
NGAVRASHWLHKKEPGFYTMHDVLNLDQI
>Mature_269_residues
MVRVAIAGAAGRMGRNLIKAVNGSQFAVLAAASERPESSLIGVDVGEMAGLGKSGILIVDDLAKVTDDFDVIIDFTLPIS
TLKNIELCQEHNKAIVIGTTGFSEPGKEIIDQASKEIPVVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIVEAHHRYKV
DAPSGTAIGMGEAIAGAMGNKLEDVAVYAREGITGERSKDEIGFATIRAGDIVGEHTAMFADIGERVEITHKATDRMTFA
NGAVRASHWLHKKEPGFYTMHDVLNLDQI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=268, Percent_Identity=63.4328358208955, Blast_Score=335, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28795; Mature: 28795

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRVAIAGAAGRMGRNLIKAVNGSQFAVLAAASERPESSLIGVDVGEMAGLGKSGILIVD
CEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCHHHHHCCCCCCEEEEE
DLAKVTDDFDVIIDFTLPISTLKNIELCQEHNKAIVIGTTGFSEPGKEIIDQASKEIPVV
CHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCEE
MAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIVEAHHRYKVDAPSGTAIGMGEAIAGAMGN
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCEECCHHHHHHHHCC
KLEDVAVYAREGITGERSKDEIGFATIRAGDIVGEHTAMFADIGERVEITHKATDRMTFA
CHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCEEEEEECCCCCEEEC
NGAVRASHWLHKKEPGFYTMHDVLNLDQI
CCCHHHHHHHHCCCCCCEEHHHHHCCCCC
>Mature Secondary Structure
MVRVAIAGAAGRMGRNLIKAVNGSQFAVLAAASERPESSLIGVDVGEMAGLGKSGILIVD
CEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCHHHHHCCCCCCEEEEE
DLAKVTDDFDVIIDFTLPISTLKNIELCQEHNKAIVIGTTGFSEPGKEIIDQASKEIPVV
CHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCEE
MAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIVEAHHRYKVDAPSGTAIGMGEAIAGAMGN
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCEECCHHHHHHHHCC
KLEDVAVYAREGITGERSKDEIGFATIRAGDIVGEHTAMFADIGERVEITHKATDRMTFA
CHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCEEEEEECCCCCEEEC
NGAVRASHWLHKKEPGFYTMHDVLNLDQI
CCCHHHHHHHHCCCCCCEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA