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The map label for this gene is carA [H]

Identifier: 59711079

GI number: 59711079

Start: 504726

End: 505883

Strand: Direct

Name: carA [H]

Synonym: VF_0472

Alternate gene names: 59711079

Gene position: 504726-505883 (Clockwise)

Preceding gene: 59711078

Following gene: 59711080

Centisome position: 17.42

GC content: 43.09

Gene sequence:

>1158_bases
TTGAGTAAATCAGCGCTGTTAGTCCTAGAAGATGGGACAGTGTTCCACGGTCAATCGATTGGAGCAGATGGCTCGGCCGT
TGGTGAAGTCGTTTTTAATACTTCGATGACGGGGTATCAAGAAATTCTCACTGATCCTTCCTATTCTCAACAAATCGTTA
CTCTCACTTATCCCCACATTGGCAATACCGGAATCAATTCCGAAGACGAAGAATCTTCTTCAATCCACGCTCAAGGCCTT
GTAATTCGCGATCTCCCTCTCTTAGCTTCAAACTTCCGCAGTGAACAAACCCTTTCTGAATATCTTAAGTCTCAAAATAT
CGTCGGCATTGCTGATATTGATACTCGTAAATTAACTCGAATTCTTCGTGAAAAAGGTGCTCAAAACGGTTGTATCGTAG
CGGGCACTAATTTAGATGAAGCATTTGCGCTTGCTCAAGCAAAAGAGTTCCCAGGTCTTAAAGGCATGGATTTAGCAAAA
GAAGTAACGACTTCTGAAGCATATCAATGGAAGCAAGGTTCTTGGACTTTGACTGGCGGTTTGCCAGAAGAAAAAGCAGA
CAGTGAATTACCATTCCACGTAGTGGCTTATGACTTTGGTGCTAAACGTAACATCTTACGTATGTTAGTTGACCGTGGTT
GTCGTTTAACGGTTGTTCCTGCCCAAACTTCTGCAGAAGAAGTATTAGCAATGAATCCAGATGGCGTATTCCTATCAAAT
GGCCCTGGTGACCCAGCACCATGTACTTACGCTATTGAAGCAACAAAAGTGTTCCTAGAAAAAGGTTTACCAATCTTTGG
TATCTGTCTTGGTCATCAAATTCTTGCTTTAGCATCTGGCGCTCAAACAGTAAAAATGAAGTTTGGTCATCATGGTGCAA
ACCACCCAGTTAAAGACTTGGAGCGTGATGTAGTAATGATCACTGCACAGAACCACGGTTTTGCAGCAGATGAAGAAACG
TTACCTGAGAATCTACGTGCGACGCACAAATCACTATTTGATGGCACTCTGCAAGGTATCCACCGTACAGATAAACCAGC
ATTCAGCTTCCAAGGTCACCCTGAAGCAAGCCCAGGTCCACACGATGCAGCGCCATTGTTTGACCATTTCATTGAATTAA
TTCAGCAGTCTATTGCTGACAAGACAAACAAAGCTTAA

Upstream 100 bases:

>100_bases
TGTCAAAAATCGAGCTTGTAGTTTGTTTTTTTGGTTTTAAAAAAATAGTTTTGCATATATATTGATGTGAAATGAATGAT
TATTATGTTTGGAGGTTGTC

Downstream 100 bases:

>100_bases
TTCGGAGTAGTAATAAGATGCCAAAACGTACTGATATTAAAAGCGTTCTAATTCTAGGTGCCGGTCCAATTGTAATCGGC
CAAGCATGTGAATTTGACTA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSKSALLVLEDGTVFHGQSIGADGSAVGEVVFNTSMTGYQEILTDPSYSQQIVTLTYPHIGNTGINSEDEESSSIHAQGL
VIRDLPLLASNFRSEQTLSEYLKSQNIVGIADIDTRKLTRILREKGAQNGCIVAGTNLDEAFALAQAKEFPGLKGMDLAK
EVTTSEAYQWKQGSWTLTGGLPEEKADSELPFHVVAYDFGAKRNILRMLVDRGCRLTVVPAQTSAEEVLAMNPDGVFLSN
GPGDPAPCTYAIEATKVFLEKGLPIFGICLGHQILALASGAQTVKMKFGHHGANHPVKDLERDVVMITAQNHGFAADEET
LPENLRATHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIQQSIADKTNKA

Sequences:

>Translated_385_residues
MSKSALLVLEDGTVFHGQSIGADGSAVGEVVFNTSMTGYQEILTDPSYSQQIVTLTYPHIGNTGINSEDEESSSIHAQGL
VIRDLPLLASNFRSEQTLSEYLKSQNIVGIADIDTRKLTRILREKGAQNGCIVAGTNLDEAFALAQAKEFPGLKGMDLAK
EVTTSEAYQWKQGSWTLTGGLPEEKADSELPFHVVAYDFGAKRNILRMLVDRGCRLTVVPAQTSAEEVLAMNPDGVFLSN
GPGDPAPCTYAIEATKVFLEKGLPIFGICLGHQILALASGAQTVKMKFGHHGANHPVKDLERDVVMITAQNHGFAADEET
LPENLRATHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIQQSIADKTNKA
>Mature_384_residues
SKSALLVLEDGTVFHGQSIGADGSAVGEVVFNTSMTGYQEILTDPSYSQQIVTLTYPHIGNTGINSEDEESSSIHAQGLV
IRDLPLLASNFRSEQTLSEYLKSQNIVGIADIDTRKLTRILREKGAQNGCIVAGTNLDEAFALAQAKEFPGLKGMDLAKE
VTTSEAYQWKQGSWTLTGGLPEEKADSELPFHVVAYDFGAKRNILRMLVDRGCRLTVVPAQTSAEEVLAMNPDGVFLSNG
PGDPAPCTYAIEATKVFLEKGLPIFGICLGHQILALASGAQTVKMKFGHHGANHPVKDLERDVVMITAQNHGFAADEETL
PENLRATHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIQQSIADKTNKA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=386, Percent_Identity=39.3782383419689, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI21361331, Length=390, Percent_Identity=35.8974358974359, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI169790915, Length=390, Percent_Identity=35.8974358974359, Blast_Score=220, Evalue=2e-57,
Organism=Escherichia coli, GI1786215, Length=376, Percent_Identity=83.2446808510638, Blast_Score=668, Evalue=0.0,
Organism=Caenorhabditis elegans, GI193204318, Length=386, Percent_Identity=36.7875647668394, Blast_Score=233, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6324878, Length=390, Percent_Identity=38.4615384615385, Blast_Score=237, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322331, Length=398, Percent_Identity=35.678391959799, Blast_Score=223, Evalue=4e-59,
Organism=Drosophila melanogaster, GI45555749, Length=394, Percent_Identity=39.3401015228426, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24642586, Length=394, Percent_Identity=39.3401015228426, Blast_Score=235, Evalue=3e-62,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41594; Mature: 41463

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSALLVLEDGTVFHGQSIGADGSAVGEVVFNTSMTGYQEILTDPSYSQQIVTLTYPHI
CCCCEEEEEECCCEEECCCCCCCCHHHHHHEECCCCCHHHHHHCCCCCCCEEEEEECCCC
GNTGINSEDEESSSIHAQGLVIRDLPLLASNFRSEQTLSEYLKSQNIVGIADIDTRKLTR
CCCCCCCCCCCCCCEEECCEEEECCHHHHHHCCCHHHHHHHHHHCCCEEEECCCHHHHHH
ILREKGAQNGCIVAGTNLDEAFALAQAKEFPGLKGMDLAKEVTTSEAYQWKQGSWTLTGG
HHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCCEEEECC
LPEEKADSELPFHVVAYDFGAKRNILRMLVDRGCRLTVVPAQTSAEEVLAMNPDGVFLSN
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCEEEEC
GPGDPAPCTYAIEATKVFLEKGLPIFGICLGHQILALASGAQTVKMKFGHHGANHPVKDL
CCCCCCCEEEEHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHH
ERDVVMITAQNHGFAADEETLPENLRATHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGP
CCCEEEEEECCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
HDAAPLFDHFIELIQQSIADKTNKA
CCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKSALLVLEDGTVFHGQSIGADGSAVGEVVFNTSMTGYQEILTDPSYSQQIVTLTYPHI
CCCEEEEEECCCEEECCCCCCCCHHHHHHEECCCCCHHHHHHCCCCCCCEEEEEECCCC
GNTGINSEDEESSSIHAQGLVIRDLPLLASNFRSEQTLSEYLKSQNIVGIADIDTRKLTR
CCCCCCCCCCCCCCEEECCEEEECCHHHHHHCCCHHHHHHHHHHCCCEEEECCCHHHHHH
ILREKGAQNGCIVAGTNLDEAFALAQAKEFPGLKGMDLAKEVTTSEAYQWKQGSWTLTGG
HHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCCEEEECC
LPEEKADSELPFHVVAYDFGAKRNILRMLVDRGCRLTVVPAQTSAEEVLAMNPDGVFLSN
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCEEEEC
GPGDPAPCTYAIEATKVFLEKGLPIFGICLGHQILALASGAQTVKMKFGHHGANHPVKDL
CCCCCCCEEEEHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHH
ERDVVMITAQNHGFAADEETLPENLRATHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGP
CCCEEEEEECCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
HDAAPLFDHFIELIQQSIADKTNKA
CCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA