Click here to switch to the map view.

The map label for this gene is galU [H]

Identifier: 59710949

GI number: 59710949

Start: 371327

End: 372196

Strand: Reverse

Name: galU [H]

Synonym: VF_0342

Alternate gene names: 59710949

Gene position: 372196-371327 (Counterclockwise)

Preceding gene: 59710950

Following gene: 59710948

Centisome position: 12.85

GC content: 38.28

Gene sequence:

>870_bases
ATGATCAAAAAATGTTTATTTCCTGCCGCAGGCTACGGCACACGCTTTTTACCAGCAACAAAATCAATGCCAAAAGAAAT
GATGCCTGTTGTAAACAAGCCTCTTATTGAATACGGTGTTGAAGAAGCAATCAATGCTGGTATGGACGGTATGTGTATTG
TTACTGGTCGTGGTAAACATTCTTTAATGGATCACTTTGATAAAAACTACGAATTAGAGCACCAAATCAGTGGTACAAAC
AAAGAAGAACTTCTTGAAGATGTTCGCGAACTGATTGATTCAGCCCACTTCACTTATATTCGTCAACGTGAAATGAAAGG
CTTAGGTCATGCAATTTTAACAGGTCGTGAACTTGTAGGTGATGAACCTTTCGCAGTTGTACTTGCTGATGACTTATGTG
TGAACGAAGAGCAAGGCGTATTGGCTCAAATGGTTGCTTTATACAAGCAATTCCGTTGTTCTATCGTTGCTGTAGAAGAA
GTTCCAGACAACGAAACGCACAAATATGGTGTGATTTCTGGTGAAATGATCAAAGATGATTTATACCGTGTTGATAACAT
GGTAGAAAAACCAGAGCCAGGAACAGCACCAAGCAACCTAGCTATTATTGGTCGTTACATCCTAACTCCTGATATTTTTG
AGTTAATCGAGCAGACAGAACCAGGTAAAGGCGGTGAAATTCAAATCACCGATGCTCTACTAAAACAAGCACAATCAGGC
TGTGTTTTAGCTTATAAATTTAAAGGTAAGCGTTTTGACTGTGGCAGCGTTGAAGGTTATATCGAAGCAACGAACCACTG
TTATGAGAACATTTATCTAAAAGATAAAAAATCATCAGAATTAGCAAAAAAAGTAACGGGTAAAAAATAA

Upstream 100 bases:

>100_bases
TCATTTCATACACCTAAGTCGATAAACTGCGTCGATAATAATGAGACTCAAAATGAAGCCTCCCCTAAATTTTTAAATAT
TGTCTTTCTAGGACTGAATT

Downstream 100 bases:

>100_bases
CCCTAACACTTAAATAAATAATAACGCCCTATGTTTAGACATGGGGCGTTTTGTTTTACCTCTCTAATCCCACCATCACT
ACACTGTTTTTTTATCCAGT

Product: glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MIKKCLFPAAGYGTRFLPATKSMPKEMMPVVNKPLIEYGVEEAINAGMDGMCIVTGRGKHSLMDHFDKNYELEHQISGTN
KEELLEDVRELIDSAHFTYIRQREMKGLGHAILTGRELVGDEPFAVVLADDLCVNEEQGVLAQMVALYKQFRCSIVAVEE
VPDNETHKYGVISGEMIKDDLYRVDNMVEKPEPGTAPSNLAIIGRYILTPDIFELIEQTEPGKGGEIQITDALLKQAQSG
CVLAYKFKGKRFDCGSVEGYIEATNHCYENIYLKDKKSSELAKKVTGKK

Sequences:

>Translated_289_residues
MIKKCLFPAAGYGTRFLPATKSMPKEMMPVVNKPLIEYGVEEAINAGMDGMCIVTGRGKHSLMDHFDKNYELEHQISGTN
KEELLEDVRELIDSAHFTYIRQREMKGLGHAILTGRELVGDEPFAVVLADDLCVNEEQGVLAQMVALYKQFRCSIVAVEE
VPDNETHKYGVISGEMIKDDLYRVDNMVEKPEPGTAPSNLAIIGRYILTPDIFELIEQTEPGKGGEIQITDALLKQAQSG
CVLAYKFKGKRFDCGSVEGYIEATNHCYENIYLKDKKSSELAKKVTGKK
>Mature_289_residues
MIKKCLFPAAGYGTRFLPATKSMPKEMMPVVNKPLIEYGVEEAINAGMDGMCIVTGRGKHSLMDHFDKNYELEHQISGTN
KEELLEDVRELIDSAHFTYIRQREMKGLGHAILTGRELVGDEPFAVVLADDLCVNEEQGVLAQMVALYKQFRCSIVAVEE
VPDNETHKYGVISGEMIKDDLYRVDNMVEKPEPGTAPSNLAIIGRYILTPDIFELIEQTEPGKGGEIQITDALLKQAQSG
CVLAYKFKGKRFDCGSVEGYIEATNHCYENIYLKDKKSSELAKKVTGKK

Specific function: May play a role in stationary phase survival [H]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=271, Percent_Identity=43.5424354243542, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1788355, Length=269, Percent_Identity=37.546468401487, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1790224, Length=267, Percent_Identity=26.5917602996255, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788351, Length=273, Percent_Identity=25.2747252747253, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32249; Mature: 32249

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKCLFPAAGYGTRFLPATKSMPKEMMPVVNKPLIEYGVEEAINAGMDGMCIVTGRGKH
CCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCH
SLMDHFDKNYELEHQISGTNKEELLEDVRELIDSAHFTYIRQREMKGLGHAILTGRELVG
HHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHC
DEPFAVVLADDLCVNEEQGVLAQMVALYKQFRCSIVAVEEVPDNETHKYGVISGEMIKDD
CCCEEEEEECCHHCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEECEECHHHHHH
LYRVDNMVEKPEPGTAPSNLAIIGRYILTPDIFELIEQTEPGKGGEIQITDALLKQAQSG
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCC
CVLAYKFKGKRFDCGSVEGYIEATNHCYENIYLKDKKSSELAKKVTGKK
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCEECCCCHHHHHHHHCCCC
>Mature Secondary Structure
MIKKCLFPAAGYGTRFLPATKSMPKEMMPVVNKPLIEYGVEEAINAGMDGMCIVTGRGKH
CCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCH
SLMDHFDKNYELEHQISGTNKEELLEDVRELIDSAHFTYIRQREMKGLGHAILTGRELVG
HHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHC
DEPFAVVLADDLCVNEEQGVLAQMVALYKQFRCSIVAVEEVPDNETHKYGVISGEMIKDD
CCCEEEEEECCHHCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEECEECHHHHHH
LYRVDNMVEKPEPGTAPSNLAIIGRYILTPDIFELIEQTEPGKGGEIQITDALLKQAQSG
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCC
CVLAYKFKGKRFDCGSVEGYIEATNHCYENIYLKDKKSSELAKKVTGKK
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCEECCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]