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The map label for this gene is fbp [H]

Identifier: 59710871

GI number: 59710871

Start: 266962

End: 267972

Strand: Reverse

Name: fbp [H]

Synonym: VF_0264

Alternate gene names: 59710871

Gene position: 267972-266962 (Counterclockwise)

Preceding gene: 59710879

Following gene: 59710832

Centisome position: 9.25

GC content: 37.49

Gene sequence:

>1011_bases
ATGTCTGAAATAAGAACTTTAGGTGAGTTCATTGTCGCTAAACAACATGACTTCCCTCATGCAAGTGGTGAACTGTCTTC
ATTAATAGGCTCAATCAAGTTAGCAGCAAAAATCGTTAACCGCGAGATTAATAAAGCCGGATTAGTTGATATTACAGGTG
CATCTGGTGAAGAGAATATTCAAGGTGAACAGCAACAAAAATTAGATGTTTACGCTAATGATAAATTTAAATCAGCACTT
GAAGCTCGTGATCAAGTCTGTGGTGTCGCTAGTGAAGAAGAAGATGAAGCAGTTGCTTTTAATAAGGAGCTCAACAAAAA
CGCAAAATACGTTGTATTAATGGATCCATTGGATGGTTCTTCAAATATTGATGTTAATGTTTCTGTTGGTACTATCTTTT
CTATATATCGTCGTATTTCACCAATTGGAACACCGGCTACTGAAGAAGATTTCCTGCAACCGGGTCATAAACAAGTTGCT
GCTGGTTACATTATTTACGGTTCATCAACCATGCTTGTTTATACCACAGGAAATGGTGTTCATGGTTTTACTTACGACCC
TTCACTTGGTGTTTTCTGCTTATCTCACGAAAATATGCAAATCCCAAAAGACGGTAATATCTATTCTATAAATGAAGGTA
ATTACATTCGCTTCCCTGAAGGCATTAAACAATACCTTAAATTCTGCCAAGAAAGTAAACCTGAAGACAATCGCCCATAC
ACTTCACGTTATATCGGTTCTTTAGTTGCCGATTTTCACAGAAACCTTCTAAAAGGTGGTATTTATCTTTACCCAAGTAC
TCAAGCTTACCCCAATGGAAAGTTAAGATTACTGTATGAATGTAATCCAATGGCGATGCTCATTGAAGAGGCAGGTGGTA
AAGCGACCGATGGTGAACAGCGTATCTTAGATATAAAACCAAGCGAACTACATCAACGAGTGCCTTTCTTTGTTGGTTCA
ACAAATATGGTCAATAAAGTTCATGCGTTTTTAGATGAATGGCGAGATTAA

Upstream 100 bases:

>100_bases
ATGAATTACAGCAAACAGTAACACAACTACTATAAAAATAAATCAGTACCTGACCCGACTTCGCGTTGATATCTAATAAC
AGAGAATTAAAGGAATAACT

Downstream 100 bases:

>100_bases
TTAATAAATTAGAACAGTAATTTATAATGTCCAAATACAAAAAAACCGAGTCCTAAGACTCGGTTTTTTCTTAAAGCTTA
TTCTGATTACTCAGCGTCTG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSEIRTLGEFIVAKQHDFPHASGELSSLIGSIKLAAKIVNREINKAGLVDITGASGEENIQGEQQQKLDVYANDKFKSAL
EARDQVCGVASEEEDEAVAFNKELNKNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRISPIGTPATEEDFLQPGHKQVA
AGYIIYGSSTMLVYTTGNGVHGFTYDPSLGVFCLSHENMQIPKDGNIYSINEGNYIRFPEGIKQYLKFCQESKPEDNRPY
TSRYIGSLVADFHRNLLKGGIYLYPSTQAYPNGKLRLLYECNPMAMLIEEAGGKATDGEQRILDIKPSELHQRVPFFVGS
TNMVNKVHAFLDEWRD

Sequences:

>Translated_336_residues
MSEIRTLGEFIVAKQHDFPHASGELSSLIGSIKLAAKIVNREINKAGLVDITGASGEENIQGEQQQKLDVYANDKFKSAL
EARDQVCGVASEEEDEAVAFNKELNKNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRISPIGTPATEEDFLQPGHKQVA
AGYIIYGSSTMLVYTTGNGVHGFTYDPSLGVFCLSHENMQIPKDGNIYSINEGNYIRFPEGIKQYLKFCQESKPEDNRPY
TSRYIGSLVADFHRNLLKGGIYLYPSTQAYPNGKLRLLYECNPMAMLIEEAGGKATDGEQRILDIKPSELHQRVPFFVGS
TNMVNKVHAFLDEWRD
>Mature_335_residues
SEIRTLGEFIVAKQHDFPHASGELSSLIGSIKLAAKIVNREINKAGLVDITGASGEENIQGEQQQKLDVYANDKFKSALE
ARDQVCGVASEEEDEAVAFNKELNKNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRISPIGTPATEEDFLQPGHKQVAA
GYIIYGSSTMLVYTTGNGVHGFTYDPSLGVFCLSHENMQIPKDGNIYSINEGNYIRFPEGIKQYLKFCQESKPEDNRPYT
SRYIGSLVADFHRNLLKGGIYLYPSTQAYPNGKLRLLYECNPMAMLIEEAGGKATDGEQRILDIKPSELHQRVPFFVGST
NMVNKVHAFLDEWRD

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=323, Percent_Identity=44.8916408668731, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI16579888, Length=323, Percent_Identity=44.8916408668731, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI22907028, Length=320, Percent_Identity=45.3125, Blast_Score=268, Evalue=6e-72,
Organism=Escherichia coli, GI1790679, Length=333, Percent_Identity=72.972972972973, Blast_Score=516, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17508131, Length=330, Percent_Identity=46.3636363636364, Blast_Score=306, Evalue=9e-84,
Organism=Saccharomyces cerevisiae, GI6323409, Length=333, Percent_Identity=43.5435435435435, Blast_Score=274, Evalue=1e-74,
Organism=Drosophila melanogaster, GI45550998, Length=330, Percent_Identity=46.3636363636364, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI19921562, Length=330, Percent_Identity=46.3636363636364, Blast_Score=298, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37335; Mature: 37203

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIRTLGEFIVAKQHDFPHASGELSSLIGSIKLAAKIVNREINKAGLVDITGASGEENI
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
QGEQQQKLDVYANDKFKSALEARDQVCGVASEEEDEAVAFNKELNKNAKYVVLMDPLDGS
CCCHHHCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEECHHCCCCCCEEEEECCCCCC
SNIDVNVSVGTIFSIYRRISPIGTPATEEDFLQPGHKQVAAGYIIYGSSTMLVYTTGNGV
CCEEEEEEHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEEEEECCCEEEEEEECCCC
HGFTYDPSLGVFCLSHENMQIPKDGNIYSINEGNYIRFPEGIKQYLKFCQESKPEDNRPY
CCEEECCCCCEEEEECCCEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCH
TSRYIGSLVADFHRNLLKGGIYLYPSTQAYPNGKLRLLYECNPMAMLIEEAGGKATDGEQ
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCC
RILDIKPSELHQRVPFFVGSTNMVNKVHAFLDEWRD
EEEECCHHHHHHCCCEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEIRTLGEFIVAKQHDFPHASGELSSLIGSIKLAAKIVNREINKAGLVDITGASGEENI
CHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
QGEQQQKLDVYANDKFKSALEARDQVCGVASEEEDEAVAFNKELNKNAKYVVLMDPLDGS
CCCHHHCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEECHHCCCCCCEEEEECCCCCC
SNIDVNVSVGTIFSIYRRISPIGTPATEEDFLQPGHKQVAAGYIIYGSSTMLVYTTGNGV
CCEEEEEEHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEEEEECCCEEEEEEECCCC
HGFTYDPSLGVFCLSHENMQIPKDGNIYSINEGNYIRFPEGIKQYLKFCQESKPEDNRPY
CCEEECCCCCEEEEECCCEECCCCCCEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCH
TSRYIGSLVADFHRNLLKGGIYLYPSTQAYPNGKLRLLYECNPMAMLIEEAGGKATDGEQ
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCC
RILDIKPSELHQRVPFFVGSTNMVNKVHAFLDEWRD
EEEECCHHHHHHCCCEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA