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The map label for this gene is avtA [H]

Identifier: 59710621

GI number: 59710621

Start: 14539

End: 15786

Strand: Reverse

Name: avtA [H]

Synonym: VF_0014

Alternate gene names: 59710621

Gene position: 15786-14539 (Counterclockwise)

Preceding gene: 59710626

Following gene: 59710615

Centisome position: 0.54

GC content: 40.46

Gene sequence:

>1248_bases
ATGAAGTTTACTCAATTTGGCGAAAAATTTACTCGTTACAGCGGGATCACTCAATTAATGGATGATTTAAATGATGGTTT
ACGTACACCTGGAGCCATCATGCTCGGTGGTGGTAACCCTGCTGGTATTCCCGCCATGCTCGACTACTTTAAAGACGCCT
CACAAAAAATGCTCGACTCTGGTGAGCTCATTGCGGCAATGGCCAACTACGATGGTCCTCAAGGTAAAGACAGCTTTGTA
AAAGCATTAGCAAAGCTATTAAAAGAAACTTACGGTTGGGATATTTCAGAAAAAAACATCTCTTTAACGAATGGCTCTCA
AAGTGCTTTCTTTAGCTTATTCAATCTATTAGCTGGTACTTATGCGGACGGTTCAAAAAAGAAAATATTACTTCCTCTTG
CACCGGAATACATTGGGTACGCCGATTCTGAGTTGGAATTTGATAGCTTTATTTCTTATCGTCCTGAAATTGAGTTATTA
GACAATGGACTCTTTAAATATCACGTTGATTTCAGTCAACTCACCGTTGATGAATCCATCGGAGCGATTTGCGTTTCTCG
CCCTACGAACCCTACAGGTAATGTAATTACAGACGAAGAAGTCATTAAGCTAGATAAATTAGCGCGTGAAAATAACATCC
CACTGATTCTAGATAATGCTTATGGCACCCCTTTCCCGAACATTATCTTTGAAGAGGTCACACCATTCTGGAACGACAAT
ACCATCCTATGTATGAGTTTATCTAAACTAGGATTGCCGGGATTACGCTGCGGTATTGTAATTGCAAATGAGAAGATGAC
CGAAGCCATTACAAATCTAAATGGCATTATCAATCTTGCTCCAGGTAGTGTTGGTCCAGCAATGGGATTACACATGATTG
AATCCGGTGATTTATTACGTTTAAGTGAAAACGTAATACAGCCTTTCTATTGTGAAAAGTCGCAAACAGCGGTGAACATG
CTACAAACAGCGATAACTGATCCACGTTTCCGCATCCATAAACCTGAAGGTGCTATTTTCTTATGGCTATGGTTTGATGA
ACTGCCTATCACGACGATGGAACTGTACAAACGCTTGAAAGCGCGTGGTGTACTCATTGTTCCGGGTGAATACTTCTTTA
TTGGGCAAGATGACAGCTGGAAGCATGCTCATCAATGCTTACGTATGAATTACGTTCAAGATGAAGACATGATGCAAAAA
GGCATTAATATCATTGCAGAAGAAGTGTTGAGAGCGTATTCAGAGTAA

Upstream 100 bases:

>100_bases
TAAAAATGGTGATTATCTTGCCTCTTTAACTCTGTTTGGTGTTGAGGTATGTTGTTAAAACAATCAATACTCAGACTCAA
CAATTAGCGCGGTAGTCGTA

Downstream 100 bases:

>100_bases
GTCATTAAGACAGCAATCTAATCAACTCAAATAATAGCTTGTTGCTTTGGAGTCAGCAATTCTGTTTGTCATCACTAAGC
AAACAACACATACAAATGCC

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MKFTQFGEKFTRYSGITQLMDDLNDGLRTPGAIMLGGGNPAGIPAMLDYFKDASQKMLDSGELIAAMANYDGPQGKDSFV
KALAKLLKETYGWDISEKNISLTNGSQSAFFSLFNLLAGTYADGSKKKILLPLAPEYIGYADSELEFDSFISYRPEIELL
DNGLFKYHVDFSQLTVDESIGAICVSRPTNPTGNVITDEEVIKLDKLARENNIPLILDNAYGTPFPNIIFEEVTPFWNDN
TILCMSLSKLGLPGLRCGIVIANEKMTEAITNLNGIINLAPGSVGPAMGLHMIESGDLLRLSENVIQPFYCEKSQTAVNM
LQTAITDPRFRIHKPEGAIFLWLWFDELPITTMELYKRLKARGVLIVPGEYFFIGQDDSWKHAHQCLRMNYVQDEDMMQK
GINIIAEEVLRAYSE

Sequences:

>Translated_415_residues
MKFTQFGEKFTRYSGITQLMDDLNDGLRTPGAIMLGGGNPAGIPAMLDYFKDASQKMLDSGELIAAMANYDGPQGKDSFV
KALAKLLKETYGWDISEKNISLTNGSQSAFFSLFNLLAGTYADGSKKKILLPLAPEYIGYADSELEFDSFISYRPEIELL
DNGLFKYHVDFSQLTVDESIGAICVSRPTNPTGNVITDEEVIKLDKLARENNIPLILDNAYGTPFPNIIFEEVTPFWNDN
TILCMSLSKLGLPGLRCGIVIANEKMTEAITNLNGIINLAPGSVGPAMGLHMIESGDLLRLSENVIQPFYCEKSQTAVNM
LQTAITDPRFRIHKPEGAIFLWLWFDELPITTMELYKRLKARGVLIVPGEYFFIGQDDSWKHAHQCLRMNYVQDEDMMQK
GINIIAEEVLRAYSE
>Mature_415_residues
MKFTQFGEKFTRYSGITQLMDDLNDGLRTPGAIMLGGGNPAGIPAMLDYFKDASQKMLDSGELIAAMANYDGPQGKDSFV
KALAKLLKETYGWDISEKNISLTNGSQSAFFSLFNLLAGTYADGSKKKILLPLAPEYIGYADSELEFDSFISYRPEIELL
DNGLFKYHVDFSQLTVDESIGAICVSRPTNPTGNVITDEEVIKLDKLARENNIPLILDNAYGTPFPNIIFEEVTPFWNDN
TILCMSLSKLGLPGLRCGIVIANEKMTEAITNLNGIINLAPGSVGPAMGLHMIESGDLLRLSENVIQPFYCEKSQTAVNM
LQTAITDPRFRIHKPEGAIFLWLWFDELPITTMELYKRLKARGVLIVPGEYFFIGQDDSWKHAHQCLRMNYVQDEDMMQK
GINIIAEEVLRAYSE

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=415, Percent_Identity=64.3373493975904, Blast_Score=567, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 46312; Mature: 46312

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTQFGEKFTRYSGITQLMDDLNDGLRTPGAIMLGGGNPAGIPAMLDYFKDASQKMLDS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCC
GELIAAMANYDGPQGKDSFVKALAKLLKETYGWDISEKNISLTNGSQSAFFSLFNLLAGT
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCC
YADGSKKKILLPLAPEYIGYADSELEFDSFISYRPEIELLDNGLFKYHVDFSQLTVDESI
CCCCCCCEEEEEECHHHHCCCCCCCCHHHHHCCCCCEEEECCCEEEEEECHHHHHHHHCC
GAICVSRPTNPTGNVITDEEVIKLDKLARENNIPLILDNAYGTPFPNIIFEEVTPFWNDN
CEEEEECCCCCCCCEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHCCCCCCCC
TILCMSLSKLGLPGLRCGIVIANEKMTEAITNLNGIINLAPGSVGPAMGLHMIESGDLLR
EEEEEEHHHCCCCCCEEEEEEECCHHHHHHHCCCCEEEECCCCCCHHHCEEEECCCCEEE
LSENVIQPFYCEKSQTAVNMLQTAITDPRFRIHKPEGAIFLWLWFDELPITTMELYKRLK
EHHHHCCCEECCCHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
ARGVLIVPGEYFFIGQDDSWKHAHQCLRMNYVQDEDMMQKGINIIAEEVLRAYSE
HCCEEEECCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFTQFGEKFTRYSGITQLMDDLNDGLRTPGAIMLGGGNPAGIPAMLDYFKDASQKMLDS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCC
GELIAAMANYDGPQGKDSFVKALAKLLKETYGWDISEKNISLTNGSQSAFFSLFNLLAGT
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCC
YADGSKKKILLPLAPEYIGYADSELEFDSFISYRPEIELLDNGLFKYHVDFSQLTVDESI
CCCCCCCEEEEEECHHHHCCCCCCCCHHHHHCCCCCEEEECCCEEEEEECHHHHHHHHCC
GAICVSRPTNPTGNVITDEEVIKLDKLARENNIPLILDNAYGTPFPNIIFEEVTPFWNDN
CEEEEECCCCCCCCEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHCCCCCCCC
TILCMSLSKLGLPGLRCGIVIANEKMTEAITNLNGIINLAPGSVGPAMGLHMIESGDLLR
EEEEEEHHHCCCCCCEEEEEEECCHHHHHHHCCCCEEEECCCCCCHHHCEEEECCCCEEE
LSENVIQPFYCEKSQTAVNMLQTAITDPRFRIHKPEGAIFLWLWFDELPITTMELYKRLK
EHHHHCCCEECCCHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
ARGVLIVPGEYFFIGQDDSWKHAHQCLRMNYVQDEDMMQKGINIIAEEVLRAYSE
HCCEEEECCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]