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The map label for this gene is tpiA [H]

Identifier: 57238438

GI number: 57238438

Start: 1489954

End: 1490625

Strand: Reverse

Name: tpiA [H]

Synonym: CJE1588

Alternate gene names: 57238438

Gene position: 1490625-1489954 (Counterclockwise)

Preceding gene: 57238439

Following gene: 57238437

Centisome position: 83.85

GC content: 30.8

Gene sequence:

>672_bases
ATGATCTTTGCTGCAAATTTAAAATGCAATCACACAAGAGCAAGCTTTAAAATTTATGCTGAAATTTTAAATAAAACCAT
GGGAGCAAAATGTGATGATATTATCGTTTTCCCACCTAGTGTAGCATTTTTAGAAAATGAAAATAACTTCATACAAGGAG
CGCAAAATTTTTATCCTTGTGTTAATGGTGCTTTTACAGGCGAGCTTGGAAAAGAGCATTTGGACGAATTTGGGATCAAA
TGTGTTTTAATCGGGCATTCTGAAAGAAGAGCTTTAGGAGATGAAGAATTTATTAAGGCTAAATTTGATTTTGCTAAAGA
GCATGGTTATAAAATTGTTTTTTGTATAGGTGAAAATTTAGATACAAAAAATTCAGGCAAGACTTTAGAGTTTTTAAAAA
AACAACTTGAAATTATTGATTTAAATTATGAAAAACTCATCATCGCTTATGAGCCTATTTATTCTATAGGAACGGGAGTG
AGCGCACAAAGTACAGATATCGCTAAAGTGCTTGAATTTTTAGCGAGTTTAACCAAGGTACCTTTGCTTTATGGTGGAAG
TGTGAATGAAAATAATATCAAAGAAATTTTAAGTGTAAATCATTGTGGTGGAGTTTTGATAGGCTCTGCAGCTTTAAAAG
TAGAAAATTTTATAAAATTAATCAAAGGATAA

Upstream 100 bases:

>100_bases
ATGAAATGACTTTTATTTCCACTGGAGGTGGTGCTTCTCTTGAACTTATAGAAGGTAAAGAACTTCCAGGCGTAAAAGCT
TTAAGATCTAAGGAAAATGA

Downstream 100 bases:

>100_bases
AAGATGATTATGAAGGGTAAAAAAGGCCTTATTGTAGGGGTTGCGAATAATAAATCTATCGCTTATGGCATAGCAAAAGC
ATGTTTTGATCAAGGAGCCG

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MIFAANLKCNHTRASFKIYAEILNKTMGAKCDDIIVFPPSVAFLENENNFIQGAQNFYPCVNGAFTGELGKEHLDEFGIK
CVLIGHSERRALGDEEFIKAKFDFAKEHGYKIVFCIGENLDTKNSGKTLEFLKKQLEIIDLNYEKLIIAYEPIYSIGTGV
SAQSTDIAKVLEFLASLTKVPLLYGGSVNENNIKEILSVNHCGGVLIGSAALKVENFIKLIKG

Sequences:

>Translated_223_residues
MIFAANLKCNHTRASFKIYAEILNKTMGAKCDDIIVFPPSVAFLENENNFIQGAQNFYPCVNGAFTGELGKEHLDEFGIK
CVLIGHSERRALGDEEFIKAKFDFAKEHGYKIVFCIGENLDTKNSGKTLEFLKKQLEIIDLNYEKLIIAYEPIYSIGTGV
SAQSTDIAKVLEFLASLTKVPLLYGGSVNENNIKEILSVNHCGGVLIGSAALKVENFIKLIKG
>Mature_223_residues
MIFAANLKCNHTRASFKIYAEILNKTMGAKCDDIIVFPPSVAFLENENNFIQGAQNFYPCVNGAFTGELGKEHLDEFGIK
CVLIGHSERRALGDEEFIKAKFDFAKEHGYKIVFCIGENLDTKNSGKTLEFLKKQLEIIDLNYEKLIIAYEPIYSIGTGV
SAQSTDIAKVLEFLASLTKVPLLYGGSVNENNIKEILSVNHCGGVLIGSAALKVENFIKLIKG

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=235, Percent_Identity=32.3404255319149, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI226529917, Length=235, Percent_Identity=32.3404255319149, Blast_Score=109, Evalue=2e-24,
Organism=Escherichia coli, GI1790353, Length=240, Percent_Identity=34.1666666666667, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17536593, Length=235, Percent_Identity=34.0425531914894, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6320255, Length=239, Percent_Identity=34.7280334728033, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI28572008, Length=238, Percent_Identity=31.5126050420168, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI28572006, Length=238, Percent_Identity=31.5126050420168, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI28572004, Length=238, Percent_Identity=31.5126050420168, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 24634; Mature: 24634

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFAANLKCNHTRASFKIYAEILNKTMGAKCDDIIVFPPSVAFLENENNFIQGAQNFYPC
CEEEECCEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCHHCCCC
VNGAFTGELGKEHLDEFGIKCVLIGHSERRALGDEEFIKAKFDFAKEHGYKIVFCIGENL
CCCCCCCHHHHHHHHHHCCEEEEEECCHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCC
DTKNSGKTLEFLKKQLEIIDLNYEKLIIAYEPIYSIGTGVSAQSTDIAKVLEFLASLTKV
CCCCCCCHHHHHHHHHHEEECCCCEEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHHC
PLLYGGSVNENNIKEILSVNHCGGVLIGSAALKVENFIKLIKG
CEEECCCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFAANLKCNHTRASFKIYAEILNKTMGAKCDDIIVFPPSVAFLENENNFIQGAQNFYPC
CEEEECCEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCHHCCCC
VNGAFTGELGKEHLDEFGIKCVLIGHSERRALGDEEFIKAKFDFAKEHGYKIVFCIGENL
CCCCCCCHHHHHHHHHHCCEEEEEECCHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCC
DTKNSGKTLEFLKKQLEIIDLNYEKLIIAYEPIYSIGTGVSAQSTDIAKVLEFLASLTKV
CCCCCCCHHHHHHHHHHEEECCCCEEEEEECCHHHHCCCCCCCCCCHHHHHHHHHHHHHC
PLLYGGSVNENNIKEILSVNHCGGVLIGSAALKVENFIKLIKG
CEEECCCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA