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The map label for this gene is pgk [H]

Identifier: 57238439

GI number: 57238439

Start: 1490622

End: 1491824

Strand: Reverse

Name: pgk [H]

Synonym: CJE1589

Alternate gene names: 57238439

Gene position: 1491824-1490622 (Counterclockwise)

Preceding gene: 57238440

Following gene: 57238438

Centisome position: 83.91

GC content: 35.08

Gene sequence:

>1203_bases
ATGAGTGATATTATTTCTATAAAAGATATTGATTTAGCTAAGAAAAAAGTTTTTATAAGATGTGATTTTAATGTTCCTCA
AGATGATTTTTTAAACATCACTGATGATAGACGCATAAGATCAGCTATTCCTACGATAAGATATTGTTTGGATAATGGTT
GCAGTGTGATTTTAGCCTCTCATTTAGGGCGTCCAAAAGAAATTAGCTCCAAGTATTCTTTAGAACCTGTGGCTAAGCGT
CTTGCTAGACTTTTAGATAAAGAAATTATTATGGCAAAAGATGTTATCGGCGAAGATGCAAAAACCAAAGCTATGAATTT
AAAAGCAGGTGAAATTTTACTTCTTGAAAATTTACGTTTTGAAAAAGGCGAAACTAAAAATGATGAAAATTTAGCCAAAG
AACTTGCTTCTATGGTTCAAGTTTATATCAATGATGCTTTTGGAGTATGCCATAGAGCACATTCTAGCGTGGAGGCGATT
ACTAAATTCTTTGATGAAAAACACAAAGGTGCAGGATTTTTACTCCAAAAAGAAATTGATTTTGCAAGCAATCTTATCAA
ACATCCAGCACGTCCTTTTATCGCTGTTGTTGGAGGTTCAAAGGTAAGTGGAAAACTTCAAGCATTGACAAATTTATTAC
CAAAGGTAGATAAATTAATCATAGGTGGAGGTATGGCATTTACTTTTTTAAAAGCCTTAGGTTATGATATAGGAAATTCA
CTTTTAGAAGAAGAACTTTTAGAAGAAGCTAATAAAATTCTTACCAAGGGTAAAAATTTAGGAGTGAAAATTTATCTTCC
AGTAGACGTTGTAGCTGCTCCTACGTGCTCACAAGATGCGCCGATGAAATTTGTTCCAGTGCAAGAAATTCCAAATGGTT
GGATGGGTTTAGATATAGGACCTGCAAGTGTGAGGCTTTTTAAAGAGGTGATTTCTGATGCGCAAACGATTTGGTGGAAT
GGACCTATGGGTGTTTTTGAAATTGATAAATTTTCAAAAGGTAGCATTAAAATGAGTCATTATATCAGCGAAGGACATGC
AACTTCTGTTGTTGGAGGCGGTGATACGGCTGATGTGGTTGCGCGTGCAGGTGATGCAGATGAAATGACTTTTATTTCCA
CTGGAGGTGGTGCTTCTCTTGAACTTATAGAAGGTAAAGAACTTCCAGGCGTAAAAGCTTTAAGATCTAAGGAAAATGAA
TGA

Upstream 100 bases:

>100_bases
CGGATGATTTTATCAAGGTGATTGCTTGGTATGATAATGAATGGGGTTATTCAAGTCGTCTAGTAGATATGGCAGTATAT
ATTGCAAATAAGGCTTAATC

Downstream 100 bases:

>100_bases
TCTTTGCTGCAAATTTAAAATGCAATCACACAAGAGCAAGCTTTAAAATTTATGCTGAAATTTTAAATAAAACCATGGGA
GCAAAATGTGATGATATTAT

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCSVILASHLGRPKEISSKYSLEPVAKR
LARLLDKEIIMAKDVIGEDAKTKAMNLKAGEILLLENLRFEKGETKNDENLAKELASMVQVYINDAFGVCHRAHSSVEAI
TKFFDEKHKGAGFLLQKEIDFASNLIKHPARPFIAVVGGSKVSGKLQALTNLLPKVDKLIIGGGMAFTFLKALGYDIGNS
LLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPTCSQDAPMKFVPVQEIPNGWMGLDIGPASVRLFKEVISDAQTIWWN
GPMGVFEIDKFSKGSIKMSHYISEGHATSVVGGGDTADVVARAGDADEMTFISTGGGASLELIEGKELPGVKALRSKENE

Sequences:

>Translated_400_residues
MSDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCSVILASHLGRPKEISSKYSLEPVAKR
LARLLDKEIIMAKDVIGEDAKTKAMNLKAGEILLLENLRFEKGETKNDENLAKELASMVQVYINDAFGVCHRAHSSVEAI
TKFFDEKHKGAGFLLQKEIDFASNLIKHPARPFIAVVGGSKVSGKLQALTNLLPKVDKLIIGGGMAFTFLKALGYDIGNS
LLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPTCSQDAPMKFVPVQEIPNGWMGLDIGPASVRLFKEVISDAQTIWWN
GPMGVFEIDKFSKGSIKMSHYISEGHATSVVGGGDTADVVARAGDADEMTFISTGGGASLELIEGKELPGVKALRSKENE
>Mature_399_residues
SDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCSVILASHLGRPKEISSKYSLEPVAKRL
ARLLDKEIIMAKDVIGEDAKTKAMNLKAGEILLLENLRFEKGETKNDENLAKELASMVQVYINDAFGVCHRAHSSVEAIT
KFFDEKHKGAGFLLQKEIDFASNLIKHPARPFIAVVGGSKVSGKLQALTNLLPKVDKLIIGGGMAFTFLKALGYDIGNSL
LEEELLEEANKILTKGKNLGVKIYLPVDVVAAPTCSQDAPMKFVPVQEIPNGWMGLDIGPASVRLFKEVISDAQTIWWNG
PMGVFEIDKFSKGSIKMSHYISEGHATSVVGGGDTADVVARAGDADEMTFISTGGGASLELIEGKELPGVKALRSKENE

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=419, Percent_Identity=42.2434367541766, Blast_Score=328, Evalue=6e-90,
Organism=Homo sapiens, GI31543397, Length=419, Percent_Identity=42.2434367541766, Blast_Score=322, Evalue=5e-88,
Organism=Escherichia coli, GI1789294, Length=396, Percent_Identity=43.1818181818182, Blast_Score=308, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI17508823, Length=412, Percent_Identity=43.4466019417476, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6319857, Length=419, Percent_Identity=45.8233890214797, Blast_Score=338, Evalue=7e-94,
Organism=Drosophila melanogaster, GI24581203, Length=414, Percent_Identity=44.2028985507246, Blast_Score=310, Evalue=9e-85,
Organism=Drosophila melanogaster, GI17136394, Length=416, Percent_Identity=42.0673076923077, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 43650; Mature: 43519

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCSVILAS
CCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
HLGRPKEISSKYSLEPVAKRLARLLDKEIIMAKDVIGEDAKTKAMNLKAGEILLLENLRF
HCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEEEEECCCC
EKGETKNDENLAKELASMVQVYINDAFGVCHRAHSSVEAITKFFDEKHKGAGFLLQKEID
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
FASNLIKHPARPFIAVVGGSKVSGKLQALTNLLPKVDKLIIGGGMAFTFLKALGYDIGNS
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHH
LLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPTCSQDAPMKFVPVQEIPNGWMGLDIG
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEHHHCCCCCEECCCC
PASVRLFKEVISDAQTIWWNGPMGVFEIDKFSKGSIKMSHYISEGHATSVVGGGDTADVV
HHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCEEEEHHHCCCCCEEEECCCCHHHHH
ARAGDADEMTFISTGGGASLELIEGKELPGVKALRSKENE
HCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
SDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCSVILAS
CCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
HLGRPKEISSKYSLEPVAKRLARLLDKEIIMAKDVIGEDAKTKAMNLKAGEILLLENLRF
HCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEEEEECCCC
EKGETKNDENLAKELASMVQVYINDAFGVCHRAHSSVEAITKFFDEKHKGAGFLLQKEID
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
FASNLIKHPARPFIAVVGGSKVSGKLQALTNLLPKVDKLIIGGGMAFTFLKALGYDIGNS
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHH
LLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPTCSQDAPMKFVPVQEIPNGWMGLDIG
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEHHHCCCCCEECCCC
PASVRLFKEVISDAQTIWWNGPMGVFEIDKFSKGSIKMSHYISEGHATSVVGGGDTADVV
HHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCEEEEHHHCCCCCEEEECCCCHHHHH
ARAGDADEMTFISTGGGASLELIEGKELPGVKALRSKENE
HCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA